FOXD1 / FKHL8 antibody

Principal name

FOXD1 / FKHL8 antibody

Alternative names for FOXD1 / FKHL8 antibody

Forkhead box protein D1, FREAC4, Forkhead-related protein FKHL8, Forkhead-related transcription factor 4

SwissProt ID

Q16676 (Human), Q61345 (Mouse), Q63251 (Rat), Q98937 (Chick), Q9PSY4 (Xenla)

Gene ID

2297 (FOXD1), 15229

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Chk (Chicken), African clawed frog, Por (Porcine), Sh (Sheep)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Dot blot (Dot), Paraffin Sections (P)

Background of FOXD1 / FKHL8 antibody

Transcription factor required for formation of positional identity in the developing retina, regionalization of the optic chiasm and morphogenesis of the kidney. Can neuralize ectodermal cells directly By similarity. Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis. Probable transcription factor involved in embryogenesis and somatogenesis. FOXD1 is involved in regulating inflammation as well as kidney and retinal development. FOXD1 regulates the activity of NFAT and NFkB. Deficiency of FOXD1 results in multiorgan systemic inflammation, exaggerated Th cell-derived cytokine production, and T cell proliferation in autogolgous MLRs. In kidneys, FOXD1 controls the production of signals required for the normal transition of induced mesenchyme into tubular epithelium and full growth and branching of the collecting system. Deletion of FOXD1 results in renal abnormalities. FOXD2 acts as a modulator of T cell activation.

General readings

Airik,R., et al., (2006) J. Clin. Invest. 116 (3), 663-674

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FOXD1 / FKHL8 antibody

Predicted cell location: Cytoplasm, Nucleus . Positive control: Human lung cancer tissue. Recommended dilution: 1/10-50  The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using FOXD1 antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

FOXD1 / FKHL8 antibody

Gel: 8%SDS-PAGE,Lysate: 40 µg,,Primary antibody: FOXD1 Antibody at dilution 1/670 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 1 minute Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FOXD1 / FKHL8 antibody

WB Suggested Anti-FOXD1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human Lung Rabbit IgG Purified Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

FOXD1 / FKHL8 antibody

WB Suggested Anti-FOXD1 Antibody Titration: 0.0625 ug/ml; ELISA Titer: 1:312500; Positive Control: SP2/0 cell lysate Rabbit IgG Purified Hu, Ms, Por, Rt, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

FOXD1 / FKHL8 antibody

WB Suggested Anti-FOXD1 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:312500; Positive Control: SP2/0 cell lysate Rabbit IgG Purified Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FOXD1 / FKHL8 antibody

FOXD1 / FKHL8 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

FOXD1 / FKHL8 antibody

Detection limit for recombinant GST tagged FOXD1 is approximately 1ng/ml as a capture antibody. Mouse IgG2b 2C10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

FOXD1 / FKHL8 antibody

FOXD1 / FKHL8 Goat Hu, Ms E
0.1 mg / €390.00
  Abnova Taiwan Corp.

FOXD1 / FKHL8 antibody

Human Lung; WB Suggested Anti-FOXD1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Lung; FOXD1 antibody - middle region (ARP32973_P050) in Human Lung cells using Western Blot Rabbit Aff - Purified African clawed frog, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

FOXD1 / FKHL8 antibody

Mouse SP2/0; WB Suggested Anti-FOXD1 Antibody Titration: 0.0625ug/ml. ELISA Titer: 1:312500. Positive Control: SP2/0 cell lysate; FOXD1 antibody - N-terminal region (ARP36876_P050) in Mouse SP2/0 cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

FOXD1 / FKHL8 antibody

Mouse SP2/0; WB Suggested Anti-FOXD1 Antibody Titration: 1.25ug/ml. ELISA Titer: 1:312500. Positive Control: SP2/0 cell lysate; FOXD1 antibody - N-terminal region (ARP36877_T100) in Mouse SP2/0 cells using Western Blot Rabbit Aff - Purified Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

FOXD1 / FKHL8 antibody

Western Blot: FOXD1 Antibody [NBP1-30959] - Western blot analysis of FOXD1 Antibody on 293T nuclear extract, diluted at 1:500 with 10% SDS PAGE gel. Rabbit IgG Hu Dot, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

12 Item(s)

per page
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