FOXE1 / FKHL15 antibody

Principal name

FOXE1 / FKHL15 antibody

Alternative names for FOXE1 / FKHL15 antibody

FOXE2, TITF2, TTF2, HFKL5, HFKH4, TTF-2, Forkhead box protein E1, Thyroid transcription factor 2, HNF-3/fork head-like protein 5

SwissProt ID

O00358 (Human), Q5J3Q5 (Xenla), Q8R2I0 (Mouse)

Gene ID

2304 (FOXE1), 110805 (Foxe1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Frozen Sections (C), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Dot blot (Dot), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of FOXE1 / FKHL15 antibody

Forkhead box protein E1 (FOXE1) is a member of the forkhead/ winged-helix domain transcription factor family. FOXE1, also designated FKHL15 or TTF-2, complexes with TTF-1 and Pax-8 to induce thyroid follicular cell differentiation and thyroid hormone biosynthesis by regulating the expression of the sodium iodide symporter (NIS), thyroid peroxidase (TPO), thyroglobulin (TG) and the thyrotropin receptor (TSHR). FOXE1 encodes a protein that is expressed in several tissues, including thymus, adult brain, lung, liver, heart and pancreas. The chromosomal location of the FOXE1 gene on 9q22 suggests that it may be involved in squamous cell epithelioma and hereditary sensory neuropathy type I. Mutations in the FOXE1 gene lead to the development of congenital hypothyroidism, which occurs in approximately one in four thousand newborns and results in complete or partial failure of thyroid gland development. Patients who are homozygous for a missense mutation in the forkhead domain of he FOXE1 gene can also develop thyroid agenesis, cleft palate and choanal atresia. Subsequently, the FOXE1 gene may used as a marker to study these disorders.

General readings

Clifton-Bligh RJ et al. Mutation of the gene encoding human TTF-2 associated with thyroid agenesis, cleft palate and choanal atresia. Nat Genet 19:399-401 (1998). PubMed PMID: 9697705

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FOXE1 / FKHL15 antibody

Immunofluorescence analysis of A549 cells, using TTF2 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

FOXE1 / FKHL15 antibody

Western blot analysis of extracts from HUVEC cells, using TTF2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FOXE1 / FKHL15 antibody

WB Suggested Anti-Foxe1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Mouse liver Rabbit IgG Purified Bov, GP, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

FOXE1 / FKHL15 antibody

Western blot analysis on HuvEc cell lysate using TTF2 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FOXE1 / FKHL15 (C-term) antibody

Testis: Formalin-Fixed Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Bear, Bov, Bt, Elephant, Hu, Mky, Ms, Por, Prim, Rb, Rt E, P
50 µg / €470.00
  Acris Antibodies GmbH

FOXE1 / FKHL15 (C-term) antibody

AP09633PU-N FOXE1 antibody staining of Paraffin Embedded Human Thyroid Gland at 2 µg/ml. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining. Goat Aff - Purified Hu E, P
0.1 mg / €340.00
  Acris Antibodies GmbH

FOXE1 / FKHL15 antibody

Immunohistochemistry (IHC) analyzes of FoxE1 antibody (Cat.-No.: AP20398PU-N) in paraffin-embedded human RAW264.7 tissue Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

FOXE1 / FKHL15 antibody

FOXE1 / FKHL15 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

FOXE1 / FKHL15 antibody

FOXE1 / FKHL15 Goat Hu C, E
0.1 mg / €400.00
  Abnova Taiwan Corp.

FOXE1 / FKHL15 antibody

Western blot analysis of extracts from HuvEc cells, using TTF2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

FOXE1 / FKHL15 antibody

Western blot analysis of extracts from HuvEc cells, using TTF2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

FOXE1 / FKHL15 antibody

Immunofluorescence analysis of A549 cells, using TTF2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
50 µg / €205.00
  Assay Biotech

FOXE1 / FKHL15 antibody

Immunofluorescence analysis of A549 cells, using TTF2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
0.1 mg / €310.00
  Assay Biotech

FOXE1 / FKHL15 antibody

Human Muscle; WB Suggested Anti-FOXE1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human Muscle; FOXE1 antibody - middle region (ARP31705_P050) in Human Muscle cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

FOXE1 / FKHL15 (C-term) antibody

Mouse Liver; WB Suggested Anti-Foxe1 Antibody Titration: 0.2-1 ug/ml. Positive Control: Mouse liver; Foxe1 antibody - C-terminal region (ARP37606_P050) in Mouse Liver cells using Western Blot Rabbit Aff - Purified Ms WB
50 µg / €350.00
  AVIVA Systems Biology

FOXE1 / FKHL15 antibody

FOXE1 / FKHL15 Goat IgG Aff - Purified Hu E, P
0.1 mg / €400.00
  Novus Biologicals Inc.

FOXE1 / FKHL15 antibody

Immunohistochemistry: FoxE1 Antibody [NBP1-19553] -  FoxE1 Antibody [NBP1-19553] - paraffin-embedded human RAW264.7 tissue Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

FOXE1 / FKHL15 antibody

Western Blot: FOXE1 Antibody [NBP1-30960] - Western blot analysis of FOXE1 Antibody on Hela, diluted at 1:1000 with 10% SDS PAGE gel. Rabbit IgG Hu Dot, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

FOXE1 / FKHL15 antibody

FOXE1 / FKHL15 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

FOXE1 / FKHL15 antibody

FOXE1 / FKHL15 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
50 µg / €290.00
  Novus Biologicals Inc.

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