FOXE3 / FKHL12 antibody

Principal name

FOXE3 / FKHL12 antibody

Alternative names for FOXE3 / FKHL12 antibody

Forkhead box protein E3, FREAC8, Forkhead-related protein FKHL12, Forkhead-related transcription factor 8

SwissProt ID

Q13461 (Human), Q63250 (Rat), Q9QY14 (Mouse)

Gene ID

2301 (FOXE3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Enzyme Immunoassay (E)

Background of FOXE3 / FKHL12 antibody

The human forkhead-box (FOX) gene family consists of at least 43 members, including FOXE3, a 288-amino acid protein. FOXE3 is a winged-helix transcription factor that plays a crucial role during the initial stages of lens development and closure of the lens vesicle. FOXE3 may also act as a factor that promotes survival and proliferation while preventing differentiation in the lens epithelium. As the posterior cells of the lens fiber begin to differentiate, expression of FOXE3 is limited to the undifferentiated cells coating the anterior surface of the lens. Congenital primary aphakia (CPA) is a rare developmental disorder caused by a null mutation in the FOXE3 gene that is identified by the absence of a lens. The development of CPA is normally stimulated during the fourth or fifth week of human embryogenesis.

General readings

Reis, L.M., et al. Am. J. Med. Genet. A 152A (3), 582-590 (2010)
Bremond-Gignac, D., et al. Mol. Vis. 16, 1705-1711 (2010)
Ali, M., et al. Mol. Vis. 16, 1162-1168 (2010)
Anjum, I., et al. Mol. Vis. 16, 549-555 (2010)
Iseri, S.U., et al. Hum. Mutat. 30(10):1378-1386(2009)

9 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FOXE3 / FKHL12 antibody

WB Suggested Anti-FOXE3 Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

FOXE3 / FKHL12 antibody

Immunohistochemistry analyses of FOXE3 in human prostate carcinoma tissue (Formalin-fixed, Paraffin-embedded) using FOXE3 / FKHL12 antibody (Cat.-No. AP20439PU-N). Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

FOXE3 / FKHL12 (Center) antibody

Western blot analysis of FOXE3 / FKHL12 Antibody (Center) Cat.-No AP51707PU-N in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the FOXE3 antibody detected the FOXE3 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

FOXE3 / FKHL12 antibody

Western blot analysis of extracts from K562 cells, using FOXE3 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

FOXE3 / FKHL12 antibody

Western blot analysis of extracts from K562 cells, using FOXE3 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

FOXE3 / FKHL12 antibody

Human SH-SYSY; WB Suggested Anti-FOXE3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: SH-SYSY cell lysate; FOXE3 antibody - N-terminal region (ARP31700_P050) in Human SH-SYSY cells using Western Blot Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

FOXE3 / FKHL12 antibody

Human Muscle; FOXE3 antibody - C-terminal region (ARP32304_P050) in Human Muscle cells using Immunohistochemistry Rabbit Aff - Purified Hu P, WB
50 µg / €350.00
  AVIVA Systems Biology

FOXE3 / FKHL12 antibody

FOXE3 / FKHL12 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

FOXE3 / FKHL12 antibody

FOXE3 / FKHL12 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
50 µg / €290.00
  Novus Biologicals Inc.

9 Item(s)

per page
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