FOXO4 / AFX1 / MLLT7 antibody

Principal name

FOXO4 / AFX1 / MLLT7 antibody

Alternative names for FOXO4 / AFX1 / MLLT7 antibody

Forkhead box protein O4, Fork head domain transcription factor AFX1

SwissProt ID

P98177 (Human), Q9WVH3 (Mouse)

Gene ID

4303 (FOXO4)

Available reactivities

Hst (Hamster), Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Mky (Monkey), Por (Porcine)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C)

Background of FOXO4 / AFX1 / MLLT7 antibody

FKHR (for forkhead in rhabdomyosarcoma), FKHRL1, and AFX1 are members of a subfamily of the forkhead family of transcription factors. AFX1, also known as FoxO4, is expressed in a wide variety of tissues and, like other FKHR proteins, AFX1 contains a single forkhead domain and serine-proline-rich region, which mediate DNA binding. AFX1-mediated transcriptional activation is regulated by the serine/threonine kinase Akt1, which phosphorylates AFX1 (in humans, this phosphorylation can occur at several sites, including Ser 197) and in turn, sequesters AFX1 in the cytosol, thereby blocking nuclear localization and DNA binding. Genetic mutations in FKHR genes, including the t(2;13) and t(1;3) translocations, are commonly found in alveolar rhabdomyosarcomas. Additionally, the t(x;11) translocation of the AFX1 gene, which involves the fusion of a serine-proline-rich sequence of AFX1 to the carboxyterminus of a truncated MLL, results in acute lymphocytic leukemia.

General readings

Paik JH, Kollipara R, Chu G, Ji H, Xiao Y, Ding Z, Miao L, Tothova Z, Horner JW, Carrasco DR, Jiang S, Gilliland DG, Chin L, Wong WH, Castrillon DH, DePinho RA.
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis.
Cell. 2007 Jan 26;128(2):309-23.
PMID: 17254969

  1. Quick-Filters:
  2. Highly Validated (1)

Items 1 to 20 of 65 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FOXO4 / AFX1 / MLLT7 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-FOXO4 mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120 oC for 3 min, TA808579)(1:150) Mouse IgG1 OTI1A4 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FOXO4 / AFX1 / MLLT7 antibody

TA302491 (1µg/ml) staining of K562 cell lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FOXO4 / AFX1 / MLLT7 (N-term) antibody

Western blot analysis of FOXO4 in HeLa cell lysate with FOXO4 antibody at (A) 0.5 and (B) 1 ug/mL. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FOXO4 / AFX1 / MLLT7 (N-term) antibody

Western blot analysis of FOXO4 in A-20 cell lysate with FOXO4 antibody at (A) 0.5 and (B) 1 ug/mL. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FOXO4 / AFX1 / MLLT7 antibody

Predicted band size: 54 kDa . Positive control: 293 and THP1 cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lane1,2: 293 and THP1 cells Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FOXO4 / AFX1 / MLLT7 antibody

MLLT7 Antibody (R59) (Cat. #TA324822) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MLLT7 antibody detected the MLLT7 protein (arrow). Rabbit IgG Purified Hu P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

FOXO4 / AFX1 / MLLT7 antibody

Western blot analysis of AFX expression in serum treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FOXO4 / AFX1 / MLLT7 antibody

Western blot analysis of FOXO4 expression in K562 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FOXO4 / AFX1 / MLLT7 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FOXO4 (RC213185, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FOXO4.(1:2000) Mouse IgG1 OTI2C5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FOXO4 / AFX1 / MLLT7 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-FOXO4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA808593)(1:150) Mouse IgG1 OTI8A8 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FOXO4 / AFX1 / MLLT7 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FOXO4 (RC213185, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FOXO4.(1:2000) Mouse IgG1 OTI10F12 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FOXO4 / AFX1 / MLLT7 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FOXO4 (RC213185, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FOXO4.(1:2000) Mouse IgG1 OTI5A5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FOXO4 / AFX1 / MLLT7 pSer193 antibody

FOXO4 / AFX1 / MLLT7 Rabbit Purified Hst, Hu WB
0.1 mg / €460.00
  Acris Antibodies GmbH

FOXO4 / AFX1 / MLLT7 antibody

Western blot analysis of FOXO4/AFX1 in 3T3 cell lysate (Lane 1) and rat kidney tissue lysate (Lane 2). Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €370.00
  Acris Antibodies GmbH

FOXO4 / AFX1 / MLLT7 pSer197 antibody

Figure 1. Immunohistochemical analysis of paraffin- embedded human breast carcinoma tissue using AFX (phospho-Ser197) antibody AP02424PU. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €320.00
  Acris Antibodies GmbH

FOXO4 / AFX1 / MLLT7 pSer197 antibody

Figure 1. Immunohistochemical analysis of paraffin- embedded human breast carcinoma tissue using AFX (phospho-Ser197) antibody AP02424PU. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
50 µl / €240.00
  Acris Antibodies GmbH

FOXO4 / AFX1 / MLLT7 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue, using AFX antibody AP02683PU. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €270.00
  Acris Antibodies GmbH

FOXO4 / AFX1 / MLLT7 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue, using AFX antibody AP02683PU. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µl / €230.00
  Acris Antibodies GmbH

FOXO4 / AFX1 / MLLT7 pSer197 antibody

Kidney: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

FOXO4 / AFX1 / MLLT7 (59-73) antibody

Figure 1. Staining FOXO4 in Kidney by Immunohistochemistry using Formalin-Fixed Paraffin-Embedded (FFPE) tissue. Rabbit Purified Hu E, P
50 µg / €470.00
  Acris Antibodies GmbH

Items 1 to 20 of 65 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4
  • LinkedIn