FOXP2 antibody

Principal name

FOXP2 antibody

Alternative names for FOXP2 antibody

Forkhead box protein P2, CAGH44, TNRC10, CAG repeat protein 44, Trinucleotide repeat-containing gene 10 protein

SwissProt ID

O15409 (Human), P58463 (Mouse), Q4VYS1 (Xenla)

Gene ID

93986 (FOXP2), 114142 (Foxp2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Por (Porcine), Bov (Bovine), Fe (Feline), Eq (Equine), Gt (Goat), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of FOXP2 antibody

FOXP2 is an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Four alternative transcripts encoding three different isoforms have been identified.This gene encodes an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Four alternative transcripts encoding three different isoforms have been identified.

General readings

1. Arellano JI, Guadiana SM, Breunig JJ, Rakic P, Sarkisian MR. Development and distribution of neuronal cilia in mouse neocortex. J Comp Neurol. 2012 Mar 1;520(4):848-73. doi: 10.1002/cne.22793. PMID: 22020803
2. Fujita H, Sugihara I. FoxP2 expression in the cerebellum and inferior olive: Development of the transverse stripe-shaped expression pattern in the mouse cerebellar cortex. J Comp Neurol. 2012 Feb 15;520(3):656-77. doi: 10.1002/cne.22760. PMID: 21935935
3. Waclaw RR, Ehrman LA, Pierani A, Campbell K. Developmental origin of the neuronal subtypes that comprise the amygdalar fear circuit in the mouse.
J Neurosci. 2010 May 19;30(20):6944-53. PMID: 20484636
4. Miller JE, Spiteri E, Condro MC, Dosumu-Johnson RT, Geschwind DH, White SA. Birdsong decreases protein levels of FoxP2, a molecule required for human speech. J Neurophysiol. 2008 Oct;100(4):2015-25. PMID: 18701760
5. Ang ES Jr, Gluncic V, Duque A, Schafer ME, Rakic P. Prenatal exposure to ultrasound waves impacts neuronal migration in mice. Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12903-10. PMID: 16901978

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FOXP2 (C-term) antibody

  Goat Polyclonal Antibody against FOXP2  
TA302735 (0.5µg/ml) staining of human cerebellum lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FOXP2 antibody

  Goat Polyclonal Antibody against FOXP2 (Internal region)  
TA303169 (0.3µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Fe, Hu, Ms, Por, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FOXP2 antibody

  Anti-FOXP2 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm, Nucleus. Positive control: Human brain tissue. Recommended dilution: 1/5-20  The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using FOXP2 antibody at dilution 1/4, on the right is treated with the synthetic peptide. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

FOXP2 antibody

  Rabbit polyclonal FOXP2 Antibody (C-term)  
FOXP2 Antibody (C-term) (Cat. #TA324816) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the FOXP2 antibody detected FOXP2 protein (arrow). Rabbit IgG Purified Hu, Ms, Rt ICC/IF, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

FOXP2 antibody

  Rabbit anti-FOXP2 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using FOXP2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

FOXP2 antibody

  Rabbit Polyclonal Anti-FOXP2 Antibody  
WB Suggested Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 Rabbit IgG Purified Can, Eq, Gt, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

FOXP2 antibody

  Rabbit Polyclonal Anti-FOXP2 Antibody  
WB Suggested Anti-FOXP2 Antibody Titration: 0.5 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Can, Eq, Gt, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FOXP2 antibody

  Rabbit Polyclonal Anti-FOXP2 Antibody  
Western blot analysis of extract from JK, Raji and 293 cells using FOXP2 Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FOXP2 antibody

Western blot analysis using FOXP2 antibody Cat.-No AM06679SU-N against human FOXP2 (AA: 47-287) recombinant protein (Expected MW is 52.8 kDa). Mouse IgG1 5C11A8 Ascites Hu E, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

FOXP2 antibody

Western blot analysis using FOXP2 mAb against human FOXP2 (AA: 47-287) recombinant protein. (Expected MW is 52.8 kDa) Mouse IgG1 5C11A2 Ascites Hu E, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Foxp2 - mouse gene knockout kit via CRISPR

Foxp2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Foxp2 - mouse gene knockout kit via CRISPR

Foxp2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Foxp2 - mouse gene knockout kit via CRISPR

Foxp2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Foxp2 - mouse gene knockout kit via CRISPR

Foxp2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FOXP2 (transcript variant 1)

  Recombinant protein of human forkhead box P2 (FOXP2), transcript variant 1  
FOXP2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

FOXP2 overexpression lysate

FOXP2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

FOXP2 overexpression lysate

FOXP2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, FOXP2 (mGFP-tagged) - Human forkhead box P2 (FOXP2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, FOXP2 (mGFP-tagged) - Human forkhead box P2 (FOXP2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, FOXP2 (mGFP-tagged)-Human forkhead box P2 (FOXP2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, FOXP2 (mGFP-tagged)-Human forkhead box P2 (FOXP2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,620.00
  OriGene Technologies, Inc.

Lenti ORF particles, FOXP2 (mGFP-tagged) - Human forkhead box P2 (FOXP2), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, FOXP2 (mGFP-tagged) - Human forkhead box P2 (FOXP2), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

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