FPP synthetase antibody

Principal name

FPP synthetase antibody

Alternative names for FPP synthetase antibody

Farnesyl pyrophosphate synthetase, FPS, FDPS, KIAA1293, Farnesyl diphosphate synthase

SwissProt ID

P05369 (Rat), P08836 (Chick), P14324 (Human), Q8WMY2 (Bovin), Q920E5 (Mouse)

Gene ID

2224 (FDPS), 110196 (Fdps)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Frozen Sections (C)

Background of FPP synthetase antibody

FDPS is a 419 amino acid enzyme belonging to the FPP/GGPP synthetase family. Localized to cytoplasm and peroxisome, FDPS expression is regulated by phorbol esters and polyunsaturated fatty acids. FDPS assists in cholesterol biosynthesis, post-translational protein modifications and synthesis of steroid hormones in the isoprenoid pathway.FDPS catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FDPS is inactivated by interferon-induced RSAD2, which may result in the disruption of lipid rafts at the plasma membrane. Existing as a homodimer, FDPS may have anti-viral effects when inactivated by RSAD2. Reduced activity of FDPS in liver may partly be the cause of Zellweger syndrome and neonatal adrenoleukodystrophy, both of which are known to be peroxisomal deficiency diseases.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FPP synthetase (N-term) antibody

Western blot analysis of FDPS (arrow) using rabbit polyclonal FDPS Antibody (D31) (Cat. #TA324717). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FDPS gene. Rabbit Ig Purified Hu P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

FPP synthetase antibody

Western blot analysis of extracts of various cell lines, using FDPS antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

FPP synthetase antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with FDPS antibody (Center )(Cat.#AP12197PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

FPP synthetase (N-term) antibody

Western blot analysis of FDPS (arrow) using rabbit polyclonal FDPS Antibody (N-term) (Cat. #AP51646PU-N). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FDPS gene. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

FPP synthetase antibody

FDPS MaxPab polyclonal antibody. Western Blot analysis of FDPS expression in human placenta. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

FPP synthetase antibody

Immunoprecipitation of FDPS transfected lysate using anti-FDPS MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with FDPS purified MaxPab mouse polyclonal antibody (B01P) (H00002224-B01P). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

FPP synthetase antibody

Western Blot analysis of FDPS expression in transfected 293T cell line (H00002224-T02) by FDPS MaxPab polyclonal antibody.

Lane 1: FDPS transfected lysate(48.30 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

FPP synthetase antibody

FPP synthetase Mouse IgG2a 3A6 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

FPP synthetase antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with FDPS polyclonal antibody ( Cat # PAB4323 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

FPP synthetase antibody

FPP synthetase Rabbit IgG Aff - Purified Hu, Ms C, IP, P, WB
50 µg / €680.00
  Funakoshi Co., Ltd.

FPP synthetase antibody

Immunohistochemistry-Paraffin: FDPS Antibody [NBP1-89509] - Immunohistochemical staining of human liver shows cytoplasmic and nuclear positivity in hepatocytes. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FPP synthetase

FPP synthetase Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

FPP synthetase

FPP synthetase Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

FPP synthetase

FPP synthetase Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

FPP synthetase

FPP synthetase Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

FDPS (Human) IP-WB Antibody Pair

FDPS (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

FDPS 293T Cell Transient Overexpression Lysate(Denatured)

FDPS 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

FDPS overexpression lysate

FDPS overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

FDPS overexpression lysate

FDPS overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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