Fractalkine / CX3CL1 antibody

Principal name

Fractalkine / CX3CL1 antibody

Alternative names for Fractalkine / CX3CL1 antibody

Neurotactin, FKN, NTT, SCYD1, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Small-inducible cytokine D1

SwissProt ID

O35188 (Mouse), O55145 (Rat), P78423 (Human)

Gene ID

6376 (CX3CL1), 20312 (Cx3cl1), 89808

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Chicken, Goat, Rabbit, Mouse, Rat

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Functional assay (FN), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Neutralisation (NEUT)

Background of Fractalkine / CX3CL1 antibody

As the only member of intercrine delta/ CX3C family, CX3CR1 (C-X3-C motif chemokine 1) is a type I transmembrane protein with CX3C chemokine domain present on an extended glycosylated stalk and it share this unique membrane anchorage with CXCR6 ligand, CXCL16. CX3CL1 is constitutively shed from the cell surface by ADAM10 (A Disintegrin and Metalloprotease 10) and CX3CL1 cleavage is enhanced upon activation of the closely related protease TNFalpha-converting enzyme, TACE (ADAM-17). CX3CL1 is expressed in a wide variety of cell types including neurons, intestil , airway , skin epithelium cells, airway smooth muscle cells, and endothelium. It is induced by TNF and IL1 in pulmory endothelial cells and umbilical vein endothelial cells. CX3CL1 sigls through CX3CR1 (the only receptor of CX3CL1) which is expressed on monocytes, tural killer cells, T cells and smooth muscle cells. The major function of CX3CL1's soluble form is to act as chemotactic for T-cells and monocytes, but not for neutrophils, whereas, the membrane-bound form promotes adhesion of those leukocytes to endothelial cells where it may play a role in regulating leukocyte adhesion and migration processes at the endothelium. In addition to its role in chemotaxis and adhesion of leukocytes, CX3CL1 implicates in survival of multiple cell types during homeostasis and inflammation.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Fractalkine / CX3CL1 antibody

Western blot analysis of CX3CL1 in C2C12 cell lysate with CX3CL1 antibody at (A) 0.5, (B) 1 and (C) 2 mg/ml. Rabbit IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Fractalkine / CX3CL1 antibody

Western blot analysis using recombinant human Fractalkine. Lane 1: 1 µg, Lane 2: 250 ng. Rabbit Purified Hu, Ms, Rt IP, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Fractalkine / CX3CL1 antibody

Predicted cell location: Cell membrane, Cytoplasm. Positive control: Human esophagus cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CX3CL1 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Fractalkine / CX3CL1 antibody

IHC of human pancreas malignant ductal adenocarcinoma.  The recommended concentration is 0.25ug/mL with an overnight incubation at 4C.  An HRP-labeled polymer detection system was used with a DAB chromogen.  Heat induced antigen retrieval with a pH 6.0 sodium citrate buffer is recommended.    Optimal concentrations and conditions may vary. Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Fractalkine / CX3CL1 (214-226) antibody

TA329093 (0.3µg/ml) staining of Human Colorectal cancer lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Fractalkine / CX3CL1 antibody

Immunohistochemistry: CX3CL1 Antibody [TA336789] - Analysis of CX3CL in mouse brain Rabbit Purified Hu, Ms C, ICC/IF, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Fractalkine / CX3CL1 Control Peptide

Fractalkine / CX3CL1
50 µg / €160.00
  Acris Antibodies GmbH

Fractalkine / CX3CL1 antibody

Fractalkine / CX3CL1 Chicken Aff - Purified Hu, Ms, Rt C
0.1 mg / €500.00
  Acris Antibodies GmbH

Fractalkine / CX3CL1 antibody

Fractalkine / CX3CL1 Rabbit Biotin Hu E, WB
25 µg / €230.00
  Acris Antibodies GmbH

Fractalkine / CX3CL1 antibody

Fractalkine / CX3CL1 Rabbit Biotin Hu E, WB
50 µg / €340.00
  Acris Antibodies GmbH

Fractalkine / CX3CL1 antibody

Formalin-fixed, paraffin-embedded sections of human pancreas malignant ductal adenocarcinoma using Fractalkine / CX3CL1 Cat.-No PP1009P Rabbit Aff - Purified Hu E, FN, P, WB
50 µg / €230.00
  Acris Antibodies GmbH

Fractalkine / CX3CL1 antibody

Formalin-fixed, paraffin-embedded sections of human pancreas malignant ductal adenocarcinoma using Fractalkine / CX3CL1 Cat.-No PP1009P Rabbit Aff - Purified Hu E, FN, P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Fractalkine / CX3CL1 antibody

Detection limit for recombinant GST tagged CX3CL1 is approximately 0.3ng/ml as a capture antibody. Mouse IgG1 1D6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Fractalkine / CX3CL1 antibody

Western blot analysis of CX3CL1 using recombinant human CX3CL1.
Lane 1 : 1 µg.
Lane 2 : 250 ng. Rabbit Hu, Ms, Rt C, IP, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Fractalkine / CX3CL1 antibody

Western blot analysis of CX3CL1 in C2C12 cell lysate with CX3CL1 polyclonal antibody ( Cat # PAB12834 ) at 0.5, 1 and 2 mg/ml. Rabbit Hu, Ms WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Fractalkine / CX3CL1 antibody

Fractalkine / CX3CL1 Rabbit IgG Aff - Purified Hu WB
0.1 mg / €290.00
  Boster Immunoleader

Fractalkine / CX3CL1 antibody

Fractalkine / CX3CL1 Rabbit IgG Aff - Purified Ms, Rt C, P, WB
0.1 mg / €290.00
  Boster Immunoleader

Fractalkine / CX3CL1 antibody

Fractalkine / CX3CL1 Goat Aff - Purified Ms, Rt C, P, WB
0.1 mg / €450.00
  Neuromics Antibodies

Fractalkine / CX3CL1 antibody

Fractalkine / CX3CL1 Rabbit Aff - Purified Hu, Ms ICC/IF, P
0.1 ml / €270.00
  Novus Biologicals Inc.

Fractalkine / CX3CL1 antibody

Fractalkine / CX3CL1 Rabbit Aff - Purified Hu, Ms ICC/IF, P
0.1 ml / €330.00
  Novus Biologicals Inc.

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