FRMPD1 antibody

Principal name

FRMPD1 antibody

Alternative names for FRMPD1 antibody

FRMD2, KIAA0967, FERM and PDZ domain-containing protein 1, FERM domain-containing protein 2

SwissProt ID

A2AKB4 (Mouse), Q5SYB0 (Human)

Gene ID

22844 (FRMPD1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Goat, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of FRMPD1 antibody

The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain. FRMPD1 was initially identified through a yeast two-hybrid screening with Activator of G-protein signaling 3 (AGS3), a protein that acts to stabilize the GDP-bound conformation of Gai, as the bait. FRMPD1 binds to the tetratricopeptide repeat of AGS3 and stabilizes AGS3 in a membrane environment. Suppression of FRMPD1 in Cath.a-differentiated neuronal cells decreased the level of endogenous AGS3 in membrane fractions by ~50% and enhanced the inhibition of forskolin-induced increases in cAMP. Co-immunoprecipitation studies indicate that the interaction of AGS3 with FRMPD1 is mutually exclusive with the interaction of AGS3 with Gai3, suggesting that FRMPD1 may position AGS3 in the membrane where it can then interact with Galphai.

7 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FRMPD1 antibody

Western blot analysis of FRMPD1 in K562 cell lysate with FRMPD1 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FRMPD1 Control Peptide

FRMPD1
50 µg / €160.00
  Acris Antibodies GmbH

FRMPD1 antibody

Western Blot analysis of FRMPD1 expression in transfected 293T cell line (H00022844-T01) by FRMPD1 MaxPab polyclonal antibody.

Lane 1: FRMPD1 transfected lysate(173.58 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

FRMPD1 antibody

Immunofluorescence: FRMPD1 Antibody [NBP1-77082] - K562 cells with FRMPD1 antibody at 20 ug/mL._x000d_ Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

FRMPD1 antibody

Immunohistochemistry-Paraffin: FRMPD1 Antibody [NBP1-91912] Immunohistochemical staining of human colon shows strong granular cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

FRMPD1 293T Cell Transient Overexpression Lysate(Denatured)

FRMPD1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

FRMPD1 overexpression lysate

FRMPD1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

7 Item(s)

per page
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