Fucose mutarotase / FUOM antibody

Principal name

Fucose mutarotase / FUOM antibody

Alternative names for Fucose mutarotase / FUOM antibody

C10orf125

Gene ID

282969 (C10orf125)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of Fucose mutarotase / FUOM antibody

Fukutin, a secreted protein, is expressed in various tissues in normal individuals. Fukutin colocalizes with a Golgi marker and a granular cytoplasmic distribution, suggesting that fukutin passes through the Golgi before being packaged into secretory vesicles. Fukutin may be located in the extracellular matrix, where it interacts with and reinforces a large complex encompassing the outside and inside of muscle membranes; alternatively, as a secreted protein, fukutin may cause muscular dystrophy by an unknown mechanism. The fukutin gene is expressed at similar levels in control fetal and adult brain, but is much reduced in Fukuyama congenital muscular dystrophy (FCMD) brains. Fukutin deficiency affects the modification of glycosylation of DAG1 (α-dystroglycan), which then cannot localize or function properly and may be degraded or eluted from the extracellular surface membrane of the muscle fiber. FCMD is the first human disease known to be caused by an ancient retrotransposal integration. The gene which encodes fukutin maps to human chromosome 9q31.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Fucose mutarotase / FUOM antibody

Host: Rabbit; Target Name: FUOM; Sample Tissue: Fetal Heart lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Fucose mutarotase / FUOM antibody

Immunohistochemistry-Paraffin: C10orf125 Antibody [NBP1-93896] Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

FUOM overexpression lysate

FUOM overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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