Fucosyltransferase 6 antibody

Principal name

Fucosyltransferase 6 antibody

Alternative names for Fucosyltransferase 6 antibody

Fucosyltransferase VI, FUT6, FCT3A, FucT-VI, Alpha-(1,3)-fucosyltransferase, Galactoside 3-L-fucosyltransferase

SwissProt ID

P51993 (Human)

Gene ID

2528 (FUT6)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of Fucosyltransferase 6 antibody

Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles, which are reliant on adhesion molecules such as Selectins (1-3). Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion molecule recruitment and cell trafficking (4-6).

General readings

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Stern, H.M., et al. Clin. Cancer Res. 16(5):1587-1596(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Norden, R., et al. Glycobiology 19(7):776-788(2009)
Higai, K., et al. Glycoconj. J. 25(3):225-235(2008)

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