FYN-binding protein antibody

Principal name

FYN-binding protein antibody

Alternative names for FYN-binding protein antibody

FYN-T-binding protein, FYB-120/130, p120/p130, SLAP-130, SLAP130, SLP-76-associated phosphoprotein, Adhesion and degranulation promoting adaptor protein

SwissProt ID

O15117 (Human), O35601 (Mouse)

Gene ID

2533 (FYB)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat)

Available hosts

Rabbit, Goat, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of FYN-binding protein antibody

Fyb (Fyn binding protein) and the anchoring proteins SKAP55 (src kinase-associated phosphoprotein) and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn (1–3). SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells (1–3). SKAP55 contains an amino-terminal pleckstrin homology domain and a carboxy-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines (i.e. RKxxYxxY) (4,5). SKAP55-R, similar in overall structure to SKAP55, contains a coiled-coil N-terminal domain (1,2). SKAP55 associates with SLAP-130, another component of the Fyn complex, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation (6). The human Fyb gene maps to chromosome 5p13.1 and encodes a 783 amino acid protein (7).

General readings

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010)
Srivastava, R., et al. J. Biol. Chem. 285(15):11100-11105(2010)
Lehmann, R., et al. Proteomics 9(23):5288-5295(2009)
Voss, M., et al. BMC Immunol. 10, 53 (2009)
Burbach, B.J., et al. J. Immunol. 181(7):4840-4851(2008)

15 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FYN-binding protein (C-term) antibody

Western blot analysis of ADAP in K562 cell lysate with ADAP antibody at (A) 0.5 and (B) 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FYN-binding protein (N-term) antibody

Western blot analysis of ADAP in K562 cell lysate with ADAP antibody at (A) 0.5 and (B) 1 ug/mL. Rabbit IgG Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FYN-binding protein Control Peptide

FYN-binding protein
50 µg / €160.00
  Acris Antibodies GmbH

FYN-binding protein Control Peptide

FYN-binding protein
50 µg / €160.00
  Acris Antibodies GmbH

FYN-binding protein antibody

FYN-binding protein Goat Aff - Purified Bov, Can, Hu E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

FYN-binding protein (C-term) antibody

Western blot analysis of FYB Antibody (C-term) Cat.-No AP51746PU-N  in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the FYB antibody detected the FYB protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

FYN-binding protein antibody

FYN-binding protein Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

FYN-binding protein antibody

Immunocytochemistry of FYB in K-562 cells with FYB polyclonal antibody ( Cat # PAB13280 ) at 10 µg/ml. Rabbit Hu, Ms ICC/IF, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

FYN-binding protein antibody

Immunocytochemistry of FYB in K-562 cells with FYB polyclonal antibody ( Cat # PAB13281 ) at 10 µg/ml. Rabbit Hu ICC/IF, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

FYN-binding protein antibody

Western blot analysis of FYB expression in A549 (A); MDAMB435 (B); TF1 (C) whole cell lysates. Rabbit Aff - Purified Hu WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

FYN-binding protein antibody

Western blot analysis of FYB expression in A549 (A); MDAMB435 (B); TF1 (C) whole cell lysates. Rabbit Aff - Purified Hu WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

FYN-binding protein antibody

Western blot analysis of FYB expression in A549 (A); MDAMB435 (B); TF1 (C) whole cell lysates. Rabbit Aff - Purified Hu WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

FYN-binding protein antibody

Immunohistochemistry-Paraffin: FYB Antibody [NBP1-91916] Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FYN-binding protein (transcript variant 1)

FYN-binding protein Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

FYN-binding protein (transcript variant 2)

FYN-binding protein Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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