FZD2 / Frizzled-2 antibody

Principal name

FZD2 / Frizzled-2 antibody

Alternative names for FZD2 / Frizzled-2 antibody

Fz-2, hFz2, FzE2

SwissProt ID

Q08464 (Rat), Q14332 (Human), Q9IA06 (Chick), Q9JIP6 (Mouse), Q9PUU6 (Xenla)

Gene ID

2535 (FZD2), 57265 (Fzd2), 64512

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Bov (Bovine), Eq (Equine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of FZD2 / Frizzled-2 antibody

The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy-terminal Ser/Thr-XXX-Val motif. The proteins in this family function as receptors for Wnt and are generally coupled to G proteins. Frizzleds are members of the G protein-coupled receptor superfamily. Frizzled-2 is expressed in the fetal kidney and lung and in the adult ovary and colon. Frizzled-2 mediates the Wnt/cGMP/Ca2+ pathway. It binds Wnt proteins and signals by activating the release of stored calcium. Frizzled-2 expression is regulated by Angiotensin II. Activated frizzled-2 suppresses the activity of protein kinase G, and activates NFAT-dependent transcription, the phosphatidylinositol pathway and calcium sensitive enzymes.

General readings

Bazhin, A.V., et al. Cell. Mol. Life Sci. 67(5):817-828(2010)
Sato, A., et al. EMBO J. 29(1):41-54(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010)
Ollila, H.M., et al. Mol. Psychiatry 14(4):351-353(2009)
Wang, H.X., et al. Mol. Hum. Reprod. 15(1):11-17(2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FZD2 / Frizzled-2 antibody

  Rabbit Polyclonal Anti-FZD2 Antibody (N-Terminus)  
Anti-FSD2 / Frizzled 2 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu
50 µg / €400.00
  OriGene Technologies, Inc.

FZD2 / Frizzled-2 antibody

  Rabbit polyclonal anti-FZD2 antibody  
Western blot analysis of extracts from HeLa cells, using FZD2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FZD2 / Frizzled-2 antibody

  Anti-FZD2 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm,Cell membrane. Positive control: Human renal cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human renal cancer tissue using FZD2 antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

FZD2 / Frizzled-2 antibody

  Anti-FZD2 Rabbit Polyclonal Antibody  
Predicted band size: 64 kDa. Positive control: HT-29 cell lysate. Recommended dilution: 1/200-1000. (Gel: 8%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FZD2 / Frizzled-2 antibody

  Rabbit Polyclonal Anti-FZD2 Antibody  
WB Suggested Anti-FZD2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human Spleen Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

FZD2 / Frizzled-2 antibody

Western blot analysis of Frizzled-2 antibody (Cat.-No:
 AP01425PU-N) in extracts from HeLa cells. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

FZD2 / Frizzled-2 antibody

AP22449PU-N FZD2 antibody  
staining of paraffin embedded Human Thyroid Gland at 2.5 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €350.00
  Acris Antibodies GmbH

FZD2 / Frizzled-2 antibody

Immunohistochemistry: Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Purified Hu E, P
50 µg / €470.00
  Acris Antibodies GmbH

FZD2 / Frizzled-2 (C-term) antibody

Western blot analysis of FZD2 / Frizzled-2 Antibody (C-term) Cat.-No AP51747PU-N in MDA-MB231 cell line lysates (35ug/lane). This demonstrates the FZD2 antibody detected the FZD2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

FZD2 / Frizzled-2 antibody

Immunofluorescence analysis of MCF7 cells, using FZD2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

FZD2 / Frizzled-2 antibody

Immunofluorescence analysis of MCF7 cells, using FZD2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

FZD2 - human gene knockout kit via CRISPR

FZD2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

FZD2 - human gene knockout kit via CRISPR

FZD2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

FZD2 - human gene knockout kit via CRISPR

FZD2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Fzd2 - mouse gene knockout kit via CRISPR

Fzd2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Fzd2 - mouse gene knockout kit via CRISPR

Fzd2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, FZD2 (mGFP-tagged) - Human frizzled family receptor 2 (FZD2), 200 uL, >10^7 TU/mL

Lenti ORF particles, FZD2 (mGFP-tagged) - Human frizzled family receptor 2 (FZD2), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, FZD2 (Myc-DDK tagged) - Human frizzled family receptor 2 (FZD2) , 200 uL, >10^7 TU/mL

Lenti ORF particles, FZD2 (Myc-DDK tagged) - Human frizzled family receptor 2 (FZD2) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Fzd2 (GFP-tagged) - Mouse frizzled homolog 2 (Drosophila) (Fzd2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Fzd2 (GFP-tagged) - Mouse frizzled homolog 2 (Drosophila) (Fzd2), 200 uL, >10^7 TU/mL  
200 µl / €1,220.00
  OriGene Technologies, Inc.

Lenti ORF particles, Fzd2 (Myc-DDK-tagged) - Mouse frizzled homolog 2 (Drosophila) (Fzd2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Fzd2 (Myc-DDK-tagged) - Mouse frizzled homolog 2 (Drosophila) (Fzd2), 200 uL, >10^7 TU/mL  
200 µl / €1,090.00
  OriGene Technologies, Inc.

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