G protein alpha 11 / GNA11 antibody

Principal name

G protein alpha 11 / GNA11 antibody

Alternative names for G protein alpha 11 / GNA11 antibody

G alpha-11, GA11, Guanine nucleotide-binding protein subunit alpha-11, Guanine nucleotide-binding protein G(y) subunit alpha

SwissProt ID

P21278 (Mouse), P29992 (Human), P38409 (Bovin), P43444 (Xenla), P52206 (Canfa), Q2XSV9 (Pig), Q9JID2 (Rat)

Gene ID

2767 (GNA11), 1146248 (acpS)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of G protein alpha 11 / GNA11 antibody

Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (e.g., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, beta and gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of Ga subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gq class includes G alpha 15, G alpha 14, G alpha 11 and G alpha q, two of which, G alpha 11 and G alphaq, are abundant in brain and lung and present at lower levels in a variety of tissues (6).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

G protein alpha 11 / GNA11 antibody

Predicted band size: 42 kDa . Positive control: Mouse eyes tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/550 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

G protein alpha 11 / GNA11 antibody

Predicted band size: 42 kDa . Positive control: Human leiomyosarcoma tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/450 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 5 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

G protein alpha 11 / GNA11 antibody

Western Blot analysis of GNA11 expression in transfected 293T cell line (H00002767-T02) by GNA11 MaxPab polyclonal antibody.

Lane 1: GNA11 transfected lysate(42.10 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

G protein alpha 11 / GNA11

G protein alpha 11 / GNA11 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

G protein alpha 11 / GNA11

G protein alpha 11 / GNA11 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

G protein alpha 11 / GNA11

G protein alpha 11 / GNA11 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

GNA11 overexpression lysate

GNA11 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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