G0S2 antibody

Principal name

G0S2 antibody

Alternative names for G0S2 antibody

G0/G1 switch protein 2, G0/G1 switch regulatory protein 2, Putative lymphocyte G0/G1 switch gene

SwissProt ID

P27469 (Human), Q5M840 (Rat), Q61585 (Mouse)

Gene ID

50486 (G0S2)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP), Enzyme Immunoassay (E)

Background of G0S2 antibody

The G(0)-G(1) switch gene 2 (G0S2) codes for a mitochondrial protein that is important in apoptosis, lipolysis, and triaceylglycerol hydrolysis. In adipocytes, G0S2 binds to adipose triglyceride lipase and decreases the breakdown of lipid droplets. In Crohn's colitis, the presence of G0S2 is increased in correlation to the amount of non-converted lipid in waste. In squamous lung cancer, mutations in the G0S2 gene are common. In breast cancer, epigenetic silencing of G0S2 occurs, and normal apoptotic regulation of aberrant cells is negatively impacted. However, when G0S2 is not epigenetically modified, it is the best mediator of the Bcl-2/Bax heterodimer, resulting in apoptosis of cancerous cells.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

G0S2 antibody

Immunocytochemistry/Immunofluorescence: GOS2 antibody was tested at 1:50 in A431 cells with FITC (green). Nuclei were counterstained with Dapi (blue). Rabbit Purified Hu ICC/IF
50 µl / €325.00
  OriGene Technologies, Inc.

G0S2 antibody

Western Blot analysis of G0S2 expression in transfected 293T cell line (H00050486-T01) by G0S2 MaxPab polyclonal antibody.

Lane 1: G0S2 transfected lysate(11.44 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

G0S2 antibody

G0S2 Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

G0S2 antibody

G0S2 Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

G0S2 antibody

Immunohistochemistry-Paraffin: G0S2 Antibody [NBP1-86112] - Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts(spermatids and spermatozoa). Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

G0S2

G0S2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Antibody Pairs

Catalog No.    

G0S2 (Human) IP-WB Antibody Pair

G0S2 (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

G0S2 293T Cell Transient Overexpression Lysate(Denatured)

G0S2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

G0S2 overexpression lysate

G0S2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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