GAB4 antibody

Principal name

GAB4 antibody

Alternative names for GAB4 antibody

GAB2-like, GRB2-associated-binding protein 4, GRB2-associated binder 2-like, GRB2-associated binder 4, GRB2-associated-binding protein 2-like, Growth factor receptor bound protein 2-associated protein 4

SwissProt ID

Q2WGN9 (Human)

Gene ID

128954 (GAB4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Flow Cytometry (F), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of GAB4 antibody

The Gab family of adaptor proteins function as molecular scaffolds that mediate protein recruit-ment to RTKs. Cytokine/growth factor triggering of protein tyrosine kinase receptors (RTKs) initiates signaling cascades that progress to the nucleus where signals for activation, proliferation and differentiation occur. This scaffolding mechanism represents a critical link in cytokine/growth factor signaling routes. Gab 1-4 contain Pleckstrin homology and potential binding sites for SH2 and SH3 domain-containing proteins. The recruitment of signaling partners to Gab family members is phosphorylation-dependent. Insulin receptor and EGF receptor signaling are among the cascades that rely on Gab family members to elicit a nuclear response to an extracellular stimulus. Gab 4 (GRB2-associated-binding protein 4), also designated GRB2-associated-binding protein 2-like (Gab 2-like), is a 574 amino acid protein that shares 62% sequence similarity with Gab 2 and contains one Pleckstrin homology domain.

General readings

Trynka, G., et al. Gut 58(8):1078-1083(2009)

9 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GAB4 antibody

Immunohistochemistry analysis of paraffin-embedded human testis tissue using GAB4 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

GAB4 antibody

Western blot analysis of extracts from K562 cells and NIH/3T3 cells, using GCNT6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GAB4 antibody

Host: Rabbit; Target Name: GAB4; Sample Tissue: 293T Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

GAB4 (N-term) antibody

Western blot analysis of GAB4 Antibody (N-term) Cat.-No AP51754PU-N in A2058 cell line lysates (35ug/lane). This demonstrates the GAB4 antibody detected the GAB4 protein (arrow) Rabbit Ig Aff - Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GAB4 antibody

Immunohistochemistry analysis of paraffin-embedded human tesophagusis, using GAB4 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P
50 µg / €205.00
  Assay Biotech

GAB4 antibody

Immunohistochemistry analysis of paraffin-embedded human tesophagusis, using GAB4 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P
0.1 mg / €310.00
  Assay Biotech

GAB4 antibody

Immunohistochemistry-Paraffin: GAB4 Antibody [NBP1-91918] Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GAB4

GAB4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

GAB4 overexpression lysate

GAB4 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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