GABAA Receptor alpha 6 antibody

Principal name

GABAA Receptor alpha 6 antibody

Alternative names for GABAA Receptor alpha 6 antibody

GABRA6, GABRA-6, Gamma-Aminobutyric Acid Receptor subunit Alpha-6

SwissProt ID

P16305 (Mouse), P30191 (Rat), Q16445 (Human), Q90845 (Chick)

Gene ID

29708 (Gabra6), 2559 (GABRA6), 14399

Available reactivities

Ms (Mouse), Rt (Rat), Bov (Bovine), Hu (Human), Can (Canine), Chk (Chicken)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Dot blot (Dot), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of GABAA Receptor alpha 6 antibody

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six Alpha's, four Beta's and four Gamma's, plus alternative splicing variants of some of these subunits, have been identified (Olsen and Tobin, 1990; Whiting et al., 1999; Ogris et al., 2004). Injection in oocytes or mammalian cell lines of cRNA coding for Alpha- and beta-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a Gamma-subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different Alpha-subunits of the receptor (McKernan et al., 2000; Mehta and Ticku, 1998; Ogris et al., 2004; Pöltl et al., 2003). Lastly, phosphorylation of Beta-subunits of the receptor has been shown to modulate GABAA-R function (Brandon et al., 2003).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GABAA Receptor alpha 6 antibody

Western blot of rat cortex lysate showing immunolabeling of the ~57k a6-subunit of the GABAA-R. Rabbit IgG Serum Ms, Rt WB
50 µl / €325.00
  OriGene Technologies, Inc.

GABAA Receptor alpha 6 antibody

Western blot of mouse forebrain lysates from Wild Type (Control) and α6-knockout (α6-K/O) animals showing specific immunolabeling of the ~57k α6-subunit of the GABAA-R. The labeling was absent from a lysate prepared from α6-knockout animals. Rabbit IgG Aff - Purified Bov, Hu, Ms, Rt Dot, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABAA Receptor alpha 6 antibody

Western blot analysis of extracts from HeLa cells and Jurkat cells, using GABRA6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABAA Receptor alpha 6 antibody

Western blot analysis of rat brain membranes: 1. Anti-GABA(A) a6 Receptor (extracellular) antibody, (1:200). 2. Anti-GABA(A) a6 Receptor (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GABAA Receptor alpha 6 antibody

GABAA Receptor alpha 6 Rabbit IgG Purified Ms, Rt WB
0.1 ml / €510.00
  Acris Antibodies GmbH

GABAA Receptor alpha 6 antibody

Western blot (WB) analysis of GABAA Rα6 antibody (Cat.-No.: AP21175PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GABAA Receptor alpha 6 (Internal) antibody

Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with GABRA6 antibody AP22584PU-N followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Bear, Bov, Can, Elephant, Eq, Hu, Mky, Ms, Por, Prim, Rb, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

GABAA Receptor alpha 6 antibody

GABAA Receptor alpha 6 Rabbit Ms, Rt WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

GABAA Receptor alpha 6 antibody

Western blot analysis of extracts from HeLa/Jurkat cells, using GABRA6 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

GABAA Receptor alpha 6 antibody

Western blot analysis of extracts from HeLa/Jurkat cells, using GABRA6 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

GABAA Receptor alpha 6 antibody

Western blot analysis of GABRA6 expression in Jurkat (A); mouse brain (B) whole cell lysates. Rabbit Aff - Purified Chk, Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

GABAA Receptor alpha 6 antibody

Western blot analysis of GABRA6 expression in Jurkat (A); mouse brain (B) whole cell lysates. Rabbit Aff - Purified Chk, Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

GABAA Receptor alpha 6 antibody

Western blot analysis of GABRA6 expression in Jurkat (A); mouse brain (B) whole cell lysates. Rabbit Aff - Purified Chk, Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

GABAA Receptor alpha 6 (N-term) antibody

Western Blot: GABA A receptor alpha 6 Antibody [NB300-150] - Western blot of rat cortex lysate showing immunolabeling of the ~57kDa alpha 6 subunit of the GABAA-R. Rabbit Serum Ms, Rt WB
50 µl / €360.00
  Novus Biologicals Inc.

GABAA Receptor alpha 6 antibody

Western Blot: GABA A Receptor alpha 6 Antibody [NB300-196] - Detection of GABA-A alpha 6 receptor in wildtype cerebellum (5-7 ug/lane), using NB 300-196. Rabbit Purified Ms, Rt WB
0.1 ml / €380.00
  Novus Biologicals Inc.

GABAA Receptor alpha 6 antibody

GABAA Receptor alpha 6 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

GABAA Receptor alpha 6 antibody

GABAA Receptor alpha 6 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GABAA Receptor alpha 6

GABAA Receptor alpha 6 Human
2 µg / €300.00
  Abnova Taiwan Corp.

GABAA Receptor alpha 6

GABAA Receptor alpha 6 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

GABAA Receptor alpha 6

GABAA Receptor alpha 6 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

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