GABAA Receptor alpha 6 antibody

Principal name

GABAA Receptor alpha 6 antibody

Alternative names for GABAA Receptor alpha 6 antibody

GABRA6, GABRA-6, Gamma-Aminobutyric Acid Receptor subunit Alpha-6

SwissProt ID

P16305 (Mouse), P30191 (Rat), Q16445 (Human), Q90845 (Chick)

Gene ID

29708 (Gabra6), 2559 (GABRA6)

Available reactivities

Ms (Mouse), Rt (Rat), Hu (Human), Bov (Bovine), Can (Canine), Eq (Equine), Mky (Monkey), Por (Porcine), Prim (Primate), Rb (Rabbit), Bear, Chk (Chicken)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Dot blot (Dot)

Background of GABAA Receptor alpha 6 antibody

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six Alpha's, four Beta's and four Gamma's, plus alternative splicing variants of some of these subunits, have been identified (Olsen and Tobin, 1990; Whiting et al., 1999; Ogris et al., 2004). Injection in oocytes or mammalian cell lines of cRNA coding for Alpha- and beta-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a Gamma-subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different Alpha-subunits of the receptor (McKernan et al., 2000; Mehta and Ticku, 1998; Ogris et al., 2004; Pöltl et al., 2003). Lastly, phosphorylation of Beta-subunits of the receptor has been shown to modulate GABAA-R function (Brandon et al., 2003).

11 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GABAA Receptor alpha 6 antibody

  Rabbit Anti-GABAA Receptor a 6 Antibody  
Western blot of rat cortex lysate showing immunolabeling of the ~57k a6-subunit of the GABAA-R. Rabbit IgG Serum Ms, Rt WB
50 µl / €325.00
  OriGene Technologies, Inc.

GABAA Receptor alpha 6 antibody

  Rabbit Anti-GABAA Receptor a 6 Antibody  
Western blot of mouse forebrain lysates from Wild Type (Control) and α6-knockout (α6-K/O) animals showing specific immunolabeling of the ~57k α6-subunit of the GABAA-R. The labeling was absent from a lysate prepared from α6-knockout animals. Rabbit IgG Aff - Purified Bov, Hu, Ms, Rt Dot, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABAA Receptor alpha 6 antibody

  Rabbit polyclonal anti-GABRA6 antibody  
Western blot analysis of extracts from HeLa cells and Jurkat cells, using GABRA6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABAA Receptor alpha 6 antibody

  Rabbit Polyclonal Anti-GABA (A) alpha6 Receptor (extracellular)  
Western blot analysis of rat brain membranes: 1. Anti-GABA(A) a6 Receptor (extracellular) antibody, (1:200). 2. Anti-GABA(A) a6 Receptor (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GABAA Receptor alpha 6 antibody

GABAA Receptor alpha 6 Rabbit IgG Purified Ms, Rt WB
0.1 ml / €510.00
  Acris Antibodies GmbH

GABAA Receptor alpha 6 antibody

Western blot (WB) analysis of GABAA Rα6 antibody (Cat.-No.: AP21175PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GABAA Receptor alpha 6 (Internal) antibody

Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with GABRA6 antibody AP22584PU-N followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Bear, Bov, Can, Elephant, Eq, Hu, Mky, Ms, Por, Prim, Rb, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

GABAA Receptor alpha 6 antibody

Western blot analysis of extracts from HeLa/Jurkat cells, using GABRA6 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

GABAA Receptor alpha 6 antibody

Western blot analysis of extracts from HeLa/Jurkat cells, using GABRA6 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, GABRA6 (mGFP-tagged) - Human gamma-aminobutyric acid (GABA) A receptor, alpha 6 (GABRA6), 200 uL, >10^7 TU/mL

Lenti ORF particles, GABRA6 (mGFP-tagged) - Human gamma-aminobutyric acid (GABA) A receptor, alpha 6 (GABRA6), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, GABRA6 (Myc-DDK tagged) - Human gamma-aminobutyric acid (GABA) A receptor, alpha 6 (GABRA6) , 200 uL, >10^7 TU/mL

Lenti ORF particles, GABRA6 (Myc-DDK tagged) - Human gamma-aminobutyric acid (GABA) A receptor, alpha 6 (GABRA6) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

11 Item(s)

per page
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