GABBR1 antibody

Principal name

GABBR1 antibody

Alternative names for GABBR1 antibody

GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1, GPRC3A, Gamma-aminobutyric acid type B receptor subunit 1

SwissProt ID

Q9UBS5 (Human), Q9WV18 (Mouse), Q9Z0U4 (Rat)

Gene ID

2550 (GABBR1), 81657 (Gabbr1), 54393

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Mky (Monkey), Can (Canine), Por (Porcine)

Available hosts

Rabbit, Mouse, Goat

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of GABBR1 antibody

GABA (gamma-aminobutyric acid) is the major inhibitory neurotransmitter in the central nervous system and plays a crucial role in the modulation of neurol activity. The GABA transmitter interacts with three types of receptors: the ionotropic receptors, GABA (A)R and GABA (C)R, and the metabotropic GABA (B) receptor, [GABA (B)R]. The latter belongs to the G-protein-coupled receptor superfamily and mediates slow syptic inhibition in the brain and spil cord. The functiol GABA (B) receptor [GABA (B)R] is a heterodimer consisting of two subunits, the GABA (B)R1 and the GABA (B)R2. These subunits were demonstrated to have complementary roles essential for the functiol receptor. The GABA (B)R1 subunit was demonstrated to be important for agonist and antagonist binding, while GABA (B)R2 was shown to be essential for trafficking and for G-protein binding. To date, eight altertively spliced isoforms of GABA (B) R1 have been proposed. These are med 1a-1h, of which 1a and 1b are the most prominent. Only 1a, 1b, and 1c appear to act as functiol subunits. They are widespread, being expressed in testis, stomach, spil cord, and brain. Isoform 1b is also expressed in kidney and liver. Alomone labs is please to offer a highly specific antibody directed against an epitope located at the extracellular N-termil domain of rat GABA (B) R1. Anti-GABA(B) R1 (extracellular) antibody (#AGB-001) can be used in Western blot alysis and immunohistochemistry applications, and recognizes GABA(B) R1 in rat and mouse samples.

General readings

1. Thibault K  et al. Molecular mechanisms underlying the enhanced analgesic effect of oxycodone compared to morphine in chemotherapy-induced neuropathic pain. PLoS One 9:e91297 (2014). WB, IHC-Fr, IHC-FrFl ; Rat .

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GABBR1 antibody

Adult rat brain membrane immunoblot Mouse IgG1 N93A/49 Supernatant Hu, Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

GABBR1 antibody

Adult rat brain membrane immunoblot Mouse IgG1 N93A/49 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

GABBR1 antibody

Immunofluorescence of monoclonal antibody to GABBR1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG2a 2D7 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GABBR1 antibody

Western blot analysis of extracts from K562 cells, using GABBR1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABBR1 antibody

Western blot analysis of extracts from HeLa cells, using GABA B Receptor antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABBR1 (873-977) antibody

Western blot analysis of GABA(Beta)R1 in rat brain membrane tissues, using a 1:1000 dilution of the antibody Mouse IgG1 S93A-49 Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GABBR1 antibody

Western blot analysis of rat brain membranes: 1. Anti-GABA(B) R1 (extracellular) antibody , (1:200). 2. Anti-GABA(B) R1 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GABBR1 antibody

Western Blot: GABA B Receptor 1 Antibody [TA336616] - WB detection of GABA B Receptor 1 / GABA beta receptor 1 in brain lysate with antibody TA336616 at a dilution of 1:500. Rabbit Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GABBR1 antibody

Anti-GABABR1 / GABBR1 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

GABBR1 antibody

Anti-GABBR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu
50 µg / €379.00
  OriGene Technologies, Inc.

GABBR1 antibody

Western blot analysis on HeLa cell lysate using GABBR1 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GABBR1 antibody

Western blot (WB) analysis with extracts from K562 cells using GABBR1 antibody (Cat.-No. AP01268PU-N). Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GABBR1 pSer923 antibody

GABBR1 Rabbit IgG Purified Bov, Hu, Mky, Ms, Rt WB
0.1 ml / €510.00
  Acris Antibodies GmbH

GABBR1 antibody

Immunohistochemistry (IHC) analysis of GABA-B Receptor antibody (Cat.-No.: AP06128PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GABBR1 pSer923 antibody

Figure 1. Western blot of rat synaptic membrane showing specific immunolabeling of the ~102k GABAB R1 protein phosphorylated at Ser923 (control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase). The blot is identical to the control except that it was incubated in lambda-Ptase (1200 units for 30 min) before being exposed to the phospho-Ser923 GABAB antibody. The immunolabeling is completely eliminated by treatment with lambda-Ptase. Rabbit IgG Aff - Purified Bov, Hu, Ms, non-Human Primates, Rt WB
0.1 ml / €380.00
  Acris Antibodies GmbH

GABBR1 (947-961) antibody

Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Hst, Hu, Mky, Ms, Por, Prim, Rb, Rt P
50 µg / €470.00
  Acris Antibodies GmbH

GABBR1 antibody

GABBR1 Rabbit IgG Hu WB
0.1 mg / €560.00
  Abnova Taiwan Corp.

GABBR1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GABA-B Receptor Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €205.00
  Assay Biotech

GABBR1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GABA-B Receptor Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €310.00
  Assay Biotech

GABBR1 antibody

Immunofluorescence analysis of HeLa cells, using GABBR1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

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