GABBR2 antibody

Principal name

GABBR2 antibody

Alternative names for GABBR2 antibody

GABBR-2, GPR51, GPRC3B, GABA-B receptor 2, GABA-B-R2, Gb2, G-protein coupled receptor 51, HG20, Gamma-aminobutyric acid type B receptor subunit 2

SwissProt ID

O75899 (Human), O88871 (Rat), Q80T41 (Mouse)

Gene ID

9568 (GABBR2), 83633 (Gabbr2), 913847 (P0AE20)

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse), Bov (Bovine), Chk (Chicken), Mky (Monkey), Xen (Xenopus), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Goat, Rabbit, Mouse

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoelectron Microscopy (EM)

Background of GABBR2 antibody

GABA (-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B) and GABA(C) receptor. The ionotropic GABA(A) and GABA(C) receptors are ligand-gated ion channels that produce fast inhibitory syptic transmission. In contrast, the metabotropic GABA(B) receptor is coupled to G proteins that modulate slow inhibitory syptic transmission . Functiol GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 where GABA(B)R1 binds the ligand and GABA(B)R2 is the primary G protein contact site . Two isoforms of GABA(B)R1 have been cloned: GABA(B)R1a is a 130 kD protein and GABA(B)R1b is a 95 kD protein . G proteins subsequently inhibit adenyl cylase activity and modulate inositol phospholipid hydrolysis. GABA(B) receptors have both pre- and postsyptic inhibitions: presyptic GABA(B) receptors inhibit neurotransmitter release through suppression of high threshold calcium channels, while postsyptic GABA(B) receptors inhibit through coupled activation of inwardly rectifying potassium channels. In addition to syptic inhibition,GABA(B) receptors may also be involved in hippocampal long-term potentiation, slow wave sleep and muscle relaxation .

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GABBR2 pSer783 antibody

Figure 1. Western blot of rat synaptic membrane showing specific immunolabeling of the ~102 k GABAB R2 protein phosphorylated at Ser783 (control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase). The  blot is identical to the control except that it was incubated in lambda-Ptase (1200 units for 30 min) before being exposed to the phospho-Ser783 GABAB antibody. The immunolabeling is completely eliminated by treatment with lambda-Ptase. Rabbit IgG Aff - Purified Bov, Can, Chk, Hu, Ms, non-Human Primates, Rt ICC/IF, WB
0.1 ml / €380.00
  Acris Antibodies GmbH

GABBR2 antibody

adult rat brain immunohistochemistry Mouse IgG1 N81/37 Supernatant Hu, Ms, Rt EM, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

GABBR2 antibody

adult rat brain immunohistochemistry Mouse IgG1 N81/37 Purified Hu, Ms, Rt EM, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

GABBR2 antibody

Western blot analysis of extracts from HepG2 cells, using GABBR2 (Ab-893) Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABBR2 antibody

GABBR2 Mouse IgG1 S81-2 Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

GABBR2 antibody

Western blot analysis of rat brain membrane: 1. Anti-GABA(B) R2 antibody, (1:200). 2. Anti-GABA(B) R2 antibody preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GABBR2 antibody

Western Blot: GABA B Receptor 2 Antibody [TA336615] - Western Blot analysis of GABA BR2 in brain lysate, using TA336615. Rabbit Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABBR2 antibody

WB Suggested Anti-GABBR2 Antibody; Titration: 1.0 ug/ml; Positive Control: Hela Whole Cell Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

GABBR2 antibody

immunoblot against adult rat brain membranes (RBM) and membranes from GABABR2 wild-type (WT) and knockout (KO) mice probed with N81/2 (left) or N52A/42 (right) TC supe. Mouse brains courtesy of Joshua Walker and Stephen Moss (Tufts) Mouse IgG2a N81/2 Supernatant Hu, Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

GABBR2 antibody

immunoblot against adult rat brain membranes (RBM) and membranes from GABABR2 wild-type (WT) and knockout (KO) mice probed with N81/2 (left) or N52A/42 (right) TC supe. Mouse brains courtesy of Joshua Walker and Stephen Moss (Tufts) Mouse IgG2a N81/2 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

GABBR2 antibody

Western blotting analysis of GABA B receptor GB2 subunit in Rat liver (Lane 1), GB2-transfected HEK292 cells (Lane 2) and Rat brain (Lane 3) with polyclonal anti-GB2 antibody. Rabbit Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €260.00
  Acris Antibodies GmbH

GABBR2 pSer783 antibody

GABBR2 Rabbit IgG Purified Bov, Chk, Hu, Mky, Ms, Rt, Xen ICC/IF, WB
0.1 ml / €500.00
  Acris Antibodies GmbH

GABBR2 antibody

GABBR2 Rabbit IgG Hu WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

GABBR2 (C-term) antibody

Human HeLa; WB Suggested Anti-GABBR2 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Hela Whole Cell; GABBR2 antibody - C-terminal region (ARP61115_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

GABBR2 antibody

GABBR2 Goat Aff - Purified Rt C, ICC/IF, P, WB
0.1 mg / €450.00
  Neuromics Antibodies

GABBR2 pSer783 antibody

GABA B Receptor 2 [phospho Ser783] Antibody [NB100-61101].  Western blot of rat synaptic membrane showing specific immunolabeling of the ~102 k GABAB R2 protein phosphorylated at Ser783 (control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: lambda-Ptase). The blot is identical to the control except that it was incubated in lambda-Ptase (1200 units for 30 min) before being exposed to the phospho-Ser783 GABAB antibody. The immunolabeling is completely eliminated by treatment with lambda-Ptase. Rabbit IgG Aff - Purified Rt ICC/IF, WB
0.1 ml / €380.00
  Novus Biologicals Inc.

GABBR2 pSer892 antibody

Western Blot: GABA-B receptor 2 subunit Phosphospecific Antibody [NB300-170] - Western blots of (A) Cos-7 cells transiently expressing GABABR2S892A (Lanes 1), wild type GABABR2 (Lanes 2) or control untransfected cells (Lanes 3). Blots were then immunolabeled with Rabbit Anti-Phospho Ser892 (Figure A). In Figure B the membrane was pre-treated with lambda-Ptase (1200 units for 30 min) before being exposed to the anti-Ser892 GABAB receptor, R2-subunit antibody. Rabbit Purified Rt ICC/IF, WB
10 µg / €380.00
  Novus Biologicals Inc.

GABBR2 antibody

GABBR2 Rabbit Hu C, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

GABBR2 antibody

Immunohistochemistry-Paraffin: GABA B Receptor 2 Antibody [NBP1-89803] Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GABBR2

GABBR2 Human
10 µg / €540.00
  Abnova Taiwan Corp.

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