GABBR2 antibody

Principal name

GABBR2 antibody

Alternative names for GABBR2 antibody

GABBR-2, GPR51, GPRC3B, GABA-B receptor 2, GABA-B-R2, Gb2, G-protein coupled receptor 51, HG20, Gamma-aminobutyric acid type B receptor subunit 2

SwissProt ID

O75899 (Human), O88871 (Rat), Q80T41 (Mouse)

Gene ID

9568 (GABBR2), 83633 (Gabbr2), 242425

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse), Bov (Bovine), Chk (Chicken), Mky (Monkey), Xen (Xenopus), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Goat, Rabbit, Mouse

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoelectron Microscopy (EM), Enzyme Immunoassay (E)

Background of GABBR2 antibody

GABA (-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B) and GABA(C) receptor. The ionotropic GABA(A) and GABA(C) receptors are ligand-gated ion channels that produce fast inhibitory syptic transmission. In contrast, the metabotropic GABA(B) receptor is coupled to G proteins that modulate slow inhibitory syptic transmission . Functiol GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 where GABA(B)R1 binds the ligand and GABA(B)R2 is the primary G protein contact site . Two isoforms of GABA(B)R1 have been cloned: GABA(B)R1a is a 130 kD protein and GABA(B)R1b is a 95 kD protein . G proteins subsequently inhibit adenyl cylase activity and modulate inositol phospholipid hydrolysis. GABA(B) receptors have both pre- and postsyptic inhibitions: presyptic GABA(B) receptors inhibit neurotransmitter release through suppression of high threshold calcium channels, while postsyptic GABA(B) receptors inhibit through coupled activation of inwardly rectifying potassium channels. In addition to syptic inhibition,GABA(B) receptors may also be involved in hippocampal long-term potentiation, slow wave sleep and muscle relaxation .

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GABBR2 antibody

adult rat brain immunohistochemistry Mouse IgG1 N81/37 Supernatant Hu, Ms, Rt EM, ICC/IF, WB
5 ml / €460.00
  Antibodies Incorporated

NeuroMab

GABBR2 antibody

adult rat brain immunohistochemistry Mouse IgG1 N81/37 Purified Hu, Ms, Rt EM, ICC/IF, WB
0.1 ml / €540.00
  Antibodies Incorporated

NeuroMab

GABBR2 antibody

  Rabbit Anti-GABAB Receptor (Ser783), R2-Subunit Antibody (Phospho-Specific)  
Western blot of rat synaptic membrane showing specific immunolabeling of the ~102 k GABAB R2 protein phosphorylated at Ser783 (control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: λ-Ptase). The blot is identical to the control except that it was incubated in λ-Ptase (1200 units  for 30 min) before being exposed to the phospho-Ser783 GABAB antibody. The immunolabeling is completely eliminated by treatment with λ-Ptase. Rabbit IgG Purified Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABBR2 antibody

  Rabbit polyclonal GABBR2 (Ab-893) antibody  
Western blot analysis of extracts from HepG2 cells, using GABBR2 (Ab-893) Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABBR2 antibody

  Mouse Monoclonal Anti-GABA-B Receptor 2 Antibody  
GABBR2 Mouse IgG1 S81-2 Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

GABBR2 antibody

  Rabbit Polyclonal Anti-GABA (B) R2  
Western blot analysis of rat brain membrane: 1. Anti-GABA(B) R2 antibody, (1:200). 2. Anti-GABA(B) R2 antibody preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GABBR2 antibody

  Rabbit Polyclonal GABA-B R2 Antibody  
Western Blot: GABA B Receptor 2 Antibody [TA336615] - Western Blot analysis of GABA BR2 in brain lysate, using TA336615. Rabbit Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABBR2 antibody

  Rabbit Polyclonal Anti-GABBR2 Antibody  
WB Suggested Anti-GABBR2 Antibody; Titration: 1.0 ug/ml; Positive Control: Hela Whole Cell Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

GABBR2 antibody

immunoblot against adult rat brain membranes (RBM) and membranes from GABABR2 wild-type (WT) and knockout (KO) mice probed with N81/2 (left) or N52A/42 (right) TC supe. Mouse brains courtesy of Joshua Walker and Stephen Moss (Tufts) Mouse IgG2a N81/2 Supernatant Hu, Ms, Rt C, ICC/IF, WB
5 ml / €460.00
  Antibodies Incorporated

NeuroMab

GABBR2 antibody

immunoblot against adult rat brain membranes (RBM) and membranes from GABABR2 wild-type (WT) and knockout (KO) mice probed with N81/2 (left) or N52A/42 (right) TC supe. Mouse brains courtesy of Joshua Walker and Stephen Moss (Tufts) Mouse IgG2a N81/2 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €540.00
  Antibodies Incorporated

NeuroMab

GABBR2 antibody

Western blotting analysis of GABA B receptor GB2 subunit in Rat liver (Lane 1), GB2-transfected HEK292 cells (Lane 2) and Rat brain (Lane 3) with polyclonal anti-GB2 antibody. Rabbit Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €260.00
  Acris Antibodies GmbH

GABBR2 pSer783 antibody

GABBR2 Rabbit IgG Purified Bov, Chk, Hu, Mky, Ms, Rt, Xen ICC/IF, WB
0.1 ml / €500.00
  Acris Antibodies GmbH

GABBR2 antibody

GABBR2 Goat Aff - Purified Rt C, ICC/IF, P, WB
0.1 mg / €450.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

GABBR2 - human gene knockout kit via CRISPR

GABBR2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GABBR2 - human gene knockout kit via CRISPR

GABBR2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GABBR2 - human gene knockout kit via CRISPR

GABBR2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GABBR2 - human gene knockout kit via CRISPR

GABBR2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gabbr2 - mouse gene knockout kit via CRISPR

Gabbr2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Gabbr2 (GFP-tagged) - Mouse gamma-aminobutyric acid (GABA) B receptor, 2 (Gabbr2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gabbr2 (GFP-tagged) - Mouse gamma-aminobutyric acid (GABA) B receptor, 2 (Gabbr2), 200 uL, >10^7 TU/mL  
200 µl / €1,700.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Gabbr2 (GFP-tagged ORF) - Rat gamma-aminobutyric acid (GABA) B receptor 2 (Gabbr2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gabbr2 (GFP-tagged ORF) - Rat gamma-aminobutyric acid (GABA) B receptor 2 (Gabbr2), 200 uL, >10^7 TU/mL  
200 µl / €1,700.00
  OriGene Technologies, Inc.

20 Item(s)

per page
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