GABRA2 antibody

Principal name

GABRA2 antibody

Alternative names for GABRA2 antibody

GABRA-2, GABA A receptor subunit alpha-2, Gamma-aminobutyric acid receptor subunit alpha-2

SwissProt ID

P10063 (Bovin), P23576 (Rat), P26048 (Mouse), P47869 (Human)

Gene ID

2555 (GABRA2), 289606 (Gabra2), 14395

Available reactivities

Rt (Rat), Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), African clawed frog, Mky (Monkey), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of GABRA2 antibody

GABA (?-aminobutyric acid) is the major inhibitory neurotransmitter in the brain. Its production, release, reuptake and metabolism occur in the nervous system.The GABA transmitter interacts with two major types of receptors: ionotropic GABAA (GABAAR) and the metabotropic GABAB) receptors. The GABAAR belong to the ligand gated ion channel superfamily.The GABAAR, is a heteropentamer, with all of its five subunits contributing to the pore formation. To date, eight subunit isoforms were cloned: a, Ã?, ?, d, e, p, ?, and ?. Six a subunit isoforms were described to exist in mammals (a1-a6). The tive GABAA receptor, in most cases, consists of 2a, 2Ã? and 1? submit. The a subunit is the most common subunit and is expressed ubiquitously. It determines the affinities for allosteric ligands shown by GABAAR.The a2-subunit mR is strongly expressed only in the hippocampus and the hypothalamus. It occurs very early in rat brain development and declines in adulthood. The failure to complete the normal transition between the a-subunits that are highly expressed in early development (a2, a3, a5) to those expressed in adulthood (a1) might play a major role in the development of temporal lobe epilepsy.

General readings

Hadingham, K.L., et al., (1993) Mol. Pharmacol. 43:970-975.

13 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GABRA2 antibody

Western blot of 10 µg of rat cortex lysate showing immunolabeling of the ~53k a2-subunit of the GABAA-R. Rabbit IgG Purified Rt WB
50 µl / €325.00
  OriGene Technologies, Inc.

GABRA2 antibody

Western blot of mouse brain lysates from wild type (Control) and α2-knockout (α2-K/O) animals showing specific immunolabeling of the ~51k α2-subunit of the GABAA-R. The labeling was absent from a lysate prepared from α2-knockout animals. Rabbit IgG Purified Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABRA2 antibody

GABRA2 Antibody (C-term) (Cat.# TA325099) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GABRA2 antibody detected the GABRA2 protein (arrow). Rabbit IgG Purified Bov, Hu, Ms, Rt F, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

GABRA2 antibody

Western blot analysis of extracts of various cell lines, using GABRA2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

GABRA2 antibody

Western blot analysis of rat brain membranes: 1. Anti-GABA(A) a2  Receptor antibody, (1:200). 2. Anti-GABA(A) a2 Receptor antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GABRA2 antibody

WB Suggested Anti-GABRA2 Antibody Titration: 1.25ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GABRA2 antibody

GABRA2 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

GABRA2 antibody

Human HepG2; WB Suggested Anti-GABRA2 Antibody Titration: 1.25ug/ml. ELISA Titer: 1:62500. Positive Control: HepG2 cell lysate; GABRA2 antibody - middle region (AVARP13026_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

GABRA2 antibody

Western blot analysis of GABRA2 expression in mouse brain (A); rat brain (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

GABRA2 antibody

Western blot analysis of GABRA2 expression in mouse brain (A); rat brain (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

GABRA2 antibody

Western blot analysis of GABRA2 expression in mouse brain (A); rat brain (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

GABRA2 antibody

Western Blot: GABA A receptor alpha 2 Antibody [NB300-149] - Western blot of 10 ug of rat cortex lysate showing immunolabeling of the ~53k a2-subunit of the GABAA-R. Rabbit Serum Rt WB
50 µl / €360.00
  Novus Biologicals Inc.

GABRA2 antibody

Western Blot: GABA-A receptor alpha 2 subunit Antibody [NB300-192] - Western blot of rat brain lysates from wild type (Control) and a2-knockout (a2-K/O) animals showing specific immunolabeling of the ~51k a2-subunit of the GABAA-R. The labeling was absent from a lysate prepared from a2-knockout animals. Rabbit Aff - Purified Ms, Rt WB
0.1 ml / €380.00
  Novus Biologicals Inc.

13 Item(s)

per page
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