GABRA2 antibody

Principal name

GABRA2 antibody

Alternative names for GABRA2 antibody

GABRA-2, GABA A receptor subunit alpha-2, Gamma-aminobutyric acid receptor subunit alpha-2

SwissProt ID

P10063 (Bovin), P23576 (Rat), P26048 (Mouse), P47869 (Human)

Gene ID

2555 (GABRA2), 289606 (Gabra2), 14395

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), African clawed frog

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of GABRA2 antibody

GABA (?-aminobutyric acid) is the major inhibitory neurotransmitter in the brain. Its production, release, reuptake and metabolism occur in the nervous system.The GABA transmitter interacts with two major types of receptors: ionotropic GABAA (GABAAR) and the metabotropic GABAB) receptors. The GABAAR belong to the ligand gated ion channel superfamily.The GABAAR, is a heteropentamer, with all of its five subunits contributing to the pore formation. To date, eight subunit isoforms were cloned: a, Ã?, ?, d, e, p, ?, and ?. Six a subunit isoforms were described to exist in mammals (a1-a6). The tive GABAA receptor, in most cases, consists of 2a, 2Ã? and 1? submit. The a subunit is the most common subunit and is expressed ubiquitously. It determines the affinities for allosteric ligands shown by GABAAR.The a2-subunit mR is strongly expressed only in the hippocampus and the hypothalamus. It occurs very early in rat brain development and declines in adulthood. The failure to complete the normal transition between the a-subunits that are highly expressed in early development (a2, a3, a5) to those expressed in adulthood (a1) might play a major role in the development of temporal lobe epilepsy.

General readings

Hadingham, K.L., et al., (1993) Mol. Pharmacol. 43:970-975.

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GABRA2 antibody

  Rabbit Anti-GABA A Receptor a 2 Antibody  
Western blot of mouse brain lysates from wild type (Control) and α2-knockout (α2-K/O) animals showing specific immunolabeling of the ~51k α2-subunit of the GABAA-R. The labeling was absent from a lysate prepared from α2-knockout animals. Rabbit IgG Purified Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABRA2 antibody

  Rabbit polyclonal GABRA2 Antibody (C-term)  
GABRA2 Antibody (C-term) (Cat.# TA325099) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GABRA2 antibody detected the GABRA2 protein (arrow). Rabbit IgG Purified Bov, Hu, Ms, Rt F, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

GABRA2 antibody

  GABRA2 Rabbit Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using GABRA2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

GABRA2 antibody

  Rabbit Polyclonal Anti-GABA (A) alpha2 Receptor  
Western blot analysis of rat brain membranes: 1. Anti-GABA(A) a2  Receptor antibody, (1:200). 2. Anti-GABA(A) a2 Receptor antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GABRA2 antibody

  Rabbit Polyclonal Anti-GABRA2 Antibody  
WB Suggested Anti-GABRA2 Antibody Titration: 1.25ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

GABRA2 - human gene knockout kit via CRISPR

GABRA2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GABRA2 - human gene knockout kit via CRISPR

GABRA2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GABRA2 - human gene knockout kit via CRISPR

GABRA2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GABRA2 - human gene knockout kit via CRISPR

GABRA2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gabra2 - mouse gene knockout kit via CRISPR

Gabra2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Gabra2 - mouse gene knockout kit via CRISPR

Gabra2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gabra2 - mouse gene knockout kit via CRISPR

Gabra2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gabra2 - mouse gene knockout kit via CRISPR

Gabra2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, GABRA2 (mGFP-tagged) - Human gamma-aminobutyric acid (GABA) A receptor, alpha 2 (GABRA2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, GABRA2 (mGFP-tagged) - Human gamma-aminobutyric acid (GABA) A receptor, alpha 2 (GABRA2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, GABRA2 (Myc-DDK tagged) - Human gamma-aminobutyric acid (GABA) A receptor, alpha 2 (GABRA2), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, GABRA2 (Myc-DDK tagged) - Human gamma-aminobutyric acid (GABA) A receptor, alpha 2 (GABRA2), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Gabra2 (Myc-DDK-tagged) - Mouse gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 (Gabra2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gabra2 (Myc-DDK-tagged) - Mouse gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 (Gabra2), 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

16 Item(s)

per page
  • LinkedIn