GABRA3 antibody

Principal name

GABRA3 antibody

Alternative names for GABRA3 antibody

GABRA-3, GABA A Receptor subunit alpha-3, Gamma-aminobutyric acid receptor subunit alpha-3

SwissProt ID

P10064 (Bovin), P20236 (Rat), P26049 (Mouse), P34903 (Human)

Gene ID

2556 (GABRA3), 14396 (Gabra3), 24947

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), African clawed frog, Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Hst (Hamster)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Flow Cytometry (F), Frozen Sections (C)

Background of GABRA3 antibody

GABA (?-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B) and GABA(C) receptor. The ionotropic GABA(A) and GABA(C) receptors are ligand-gated ion channels that produce fast inhibitory syptic transmission. In contrast, the metabotropic GABA(B) receptor is coupled to G proteins that modulate slow inhibitory syptic transmission. Functiol GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 where GABA(B)R1 binds the ligand and GABA(B)R2 is the primary G protein contact site. Two isoforms of GABA(B)R1 have been cloned: GABA(B)R1a is a 130 kD protein and GABA(B)R1b is a 95 kD protein. G proteins subsequently inhibit adenyl cylase activity and modulate inositol phospholipid hydrolysis. GABA(B) receptors have both pre- and postsyptic inhibitions: presyptic GABA(B) receptors inhibit neurotransmitter release through suppression of high threshold calcium channels, while postsyptic GABA(B) receptors inhibit through coupled activation of inwardly rectifying potassium channels. In addition to syptic inhibition, GABA(B) receptors may also be involved in hippocampal long-term potentiation, slow wave sleep and muscle relaxation.

General readings

Chou,K.C. et al., (2004) Biochem. Biophys. Res. Commun. 316 (3), 636-642

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GABRA3 (N-term) antibody

Western blot of mouse brain lysates from wild type (Control) and α -knockout 3 (αK/O) animals showing specific immunolabeling of the ~51k α -subunit of the 3 GABA -R. The labeling was absent from a lysate prepared from α -knockout A3 animals. Rabbit IgG Aff - Purified Bov, Can, Hu, Rt, Ze C, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABRA3 antibody

Predicted band size: 55 kDa . Positive control: Rat brain and mouse brain tissue and C6 cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lane1,2,3: Rat brain and mouse brain tissue and C6 cells lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABRA3 antibody

Western blot analysis of rat brain membranes: 1. Anti-GABA(A) a3 Receptor (extracellular) antibody, (1:200). 2. Anti-GABA(A) a3 Receptor (extracellular) antibody preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GABRA3 antibody

mouse bulbus Rabbit IgG Purified Ms P
0.1 mg / €325.00
  OriGene Technologies, Inc.

GABRA3 antibody

Host: Rabbit; Target Name: Gabra3; Sample Tissue: Rat Kidney lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

GABRA3 antibody

WB Suggested Anti-GABRA3 Antibody Titration: 2.5 ug/ml; ELISA Titer: 1:312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GABRA3 antibody

Anti-GABRA3 antibody IHC of human brain, globus pallidus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hst, Hu, Ms
50 µg / €379.00
  OriGene Technologies, Inc.

GABRA3 antibody

Anti-GABRA3 antibody IHC of human brain, basal nucleus of Meynert. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu
50 µg / €379.00
  OriGene Technologies, Inc.

GABRA3 (480-492) antibody

Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Hst, Hu, Mky, Ms, Op, Platypus, Prim, Rb, Rt, Tr P
50 µg / €470.00
  Acris Antibodies GmbH

GABRA3 antibody

GABRA3 Mouse IgG2a 3C6 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

GABRA3 antibody

Western blot of mouse brain lysates from wild type (Control, lane 1) and Gabra3 knockout (alpha K/O, lane 2) animals showing specific immunolabeling of the ~51k Gabra3 subunit of the GABAA-R. The labeling was absent from a lysate prepared from Gabra3 knockout animals. Rabbit Ms, Rt WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

GABRA3 antibody

mouse bulbus; GABRA3 antibody - middle region (ARP34981_T100) in mouse bulbus cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

GABRA3 antibody

mouse bulbus; GABRA3 antibody - N-terminal region (AVARP13027_T100) in mouse bulbus cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt
0.1 mg / €310.00
  AVIVA Systems Biology

GABRA3 antibody

Western blot analysis of GABRA3 expression in mouse brain (A); rat brain (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

GABRA3 antibody

Western blot analysis of GABRA3 expression in mouse brain (A); rat brain (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

GABRA3 antibody

Western blot analysis of GABRA3 expression in mouse brain (A); rat brain (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

GABRA3 antibody

Western Blot: GABA A Receptor alpha 3 Antibody [NB100-61096] - Rat brain lysates from wild type (Control) and a3-knockout (a3-K/O) animals showing specific immunolabeling of the ~51k a3-subunit of the GABAA-R. The labeling was absent from a lysate prepared from á3-knockout animals. Rabbit IgG Aff - Purified Ms, Rt P, WB
0.1 ml / €380.00
  Novus Biologicals Inc.

GABRA3 antibody

GABRA3 Goat Aff - Purified Bov, Can, Hu, Ms, Rt P
50 µg / €480.00
  Novus Biologicals Inc.

GABRA3 antibody

Immunohistochemistry-Paraffin: GABA A Receptor alpha 3 Antibody [NBP1-87499] - Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic and nuclear positivity in neuronal cells and glial cells. Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GABRA3

GABRA3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

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