GABRA5 antibody

Principal name

GABRA5 antibody

Alternative names for GABRA5 antibody

GABA A receptor subunit alpha-5, GABRA-5, Gamma-aminobutyric acid receptor subunit alpha-5

SwissProt ID

P19969 (Rat), P31644 (Human), Q08E50 (Bovin), Q8BHJ7 (Mouse)

Gene ID

29707 (Gabra5), 2558 (GABRA5), 110886

Available reactivities

Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Hu (Human), Can (Canine), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of GABRA5 antibody

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six Alpha's, four Beta's and four Gamma's, plus alternative splicing variants of some of these subunits, have been identified (Olsen and Tobin, 1990; Whiting et al., 1999; Ogris et al., 2004). Injection in oocytes or mammalian cell lines of cRNA coding for Alpha- and beta-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a Gamma-subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different Alpha-subunits of the receptor (McKernan et al., 2000; Mehta and Ticku, 1998; Ogris et al., 2004; Pöltl et al., 2003).

General readings

Netzer,C., (2008) Am. J. Med. Genet. B Neuropsychiatr. Genet. 147 (1), 37-41

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GABRA5 antibody

  GABRA5 mouse monoclonal antibody, clone OTI1G9 (formerly 1G9)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-GABRA5 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA806473) Dilution: 1:150 Mouse IgG2b OTI1G9 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

GABRA5 antibody

  Rabbit Anti-GABAA Receptor a 5 Antibody  
Western blot of 7 μg of rat hippocampus (Hipp) showing specific immunolabeling of the ~55k α5-subunit of the GABAA-R. Rabbit IgG Aff - Purified Bov, Can, Chk, Hu, Ms, non-Human Primates, Rt, Ze WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABRA5 antibody

  Rabbit Polyclonal anti-Gabra5 antibody  
GABRA5 Rabbit IgG Purified Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

GABRA5 antibody

  Rabbit Polyclonal Anti-GABRA5 Antibody  
WB Suggested Anti-GABRA5 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

GABRA5 antibody

  Rabbit Polyclonal Anti-GABRA5 Antibody  
WB Suggested Anti-GABRA5 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

GABRA5 antibody

  GABRA5 mouse monoclonal antibody, clone OTI1C2 (formerly 1C2)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GABRA5 (RC216541, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GABRA5. Mouse IgG1 OTI1C2 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

GABRA5 antibody

  GABRA5 mouse monoclonal antibody, clone OTI3H7 (formerly 3H7)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-GABRA5 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA806596)(1:150) Mouse IgG2b OTI3H7 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

GABRA5 antibody

  GABRA5 mouse monoclonal antibody, clone OTI1G5 (formerly 1G5)  
Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-GABRA5 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA806598) Dilution: 1:150 Mouse IgG1 OTI1G5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

GABRA5 (C-term) antibody

GABRA5 Rabbit IgG Purified Ms, Rt WB
0.1 ml / €500.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

GABRA5 - human gene knockout kit via CRISPR

GABRA5 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GABRA5 - human gene knockout kit via CRISPR

GABRA5 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GABRA5 - human gene knockout kit via CRISPR

GABRA5 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GABRA5 - human gene knockout kit via CRISPR

GABRA5 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gabra5 - mouse gene knockout kit via CRISPR

Gabra5 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Gabra5 - mouse gene knockout kit via CRISPR

Gabra5 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gabra5 - mouse gene knockout kit via CRISPR

Gabra5 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gabra5 - mouse gene knockout kit via CRISPR

Gabra5 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GABRA5

  Recombinant protein of human gamma-aminobutyric acid (GABA) A receptor, alpha 5 (GABRA5)  
GABRA5 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

GABRA5 overexpression lysate

GABRA5 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

GABRA5 overexpression lysate

GABRA5 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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