GABRB1 antibody

Principal name

GABRB1 antibody

Alternative names for GABRB1 antibody

GABRB-1, GABA A receptor subunit beta-1, Gamma-aminobutyric acid receptor subunit beta-1

SwissProt ID

P08220 (Bovin), P15431 (Rat), P18505 (Human), P50571 (Mouse)

Gene ID

2560 (GABRB1), 25450 (Gabrb1), 14400

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Chk (Chicken), Ze (Zebrafish), Can (Canine), Eq (Equine), Hst (Hamster), Mky (Monkey), Prim (Primate), Rb (Rabbit), Bear, Xen (Xenopus), GP (Guinea Pig), Sh (Sheep)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of GABRB1 antibody

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces.
There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inwardrectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2).
The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (3). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (4).

General readings

Porjesz,B., et al., (2002) Proc. Natl. Acad. Sci. U.S.A. 99 (6), 3729-3733

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GABRB1 antibody

Adult rat brain immunohistochemistry Mouse IgG1 N96/55 Supernatant Hu, Ms, Rt C, ICC/IF, WB
5 ml / €460.00
  Antibodies Incorporated

NeuroMab

GABRB1 antibody

Adult rat brain immunohistochemistry Mouse IgG1 N96/55 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €540.00
  Antibodies Incorporated

NeuroMab

GABRB1 antibody

  Rabbit Anti-GABAA Receptor ß1 Antibody  
Western blot of rat cerebellar (Cb) and hippocampal (Hipp) lysates showing specific immunolabeling of the ~55k β1-subunit of the GABAA-R. Rabbit IgG Aff - Purified Can, Chk, Hu, Ms, non-Human Primates, Rt, Xen, Ze WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABRB1 antibody

  Anti-GABRB1 Rabbit Polyclonal Antibody  
Predicted band size: 54 kDa . Positive control: PC12 cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lane1: Treated with the peptide Lane2: PC12 cells lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABRB1 antibody

  Rabbit Polyclonal GABA-RB (Ser434) Antibody (Phospho-specific)  
Western blot analysis of GABA-RB phosphorylation expression in COS7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABRB1 (327-450) antibody

  Mouse Monoclonal Anti-GABA(A) Receptor beta1 Antibody  
Western blot analysis of GABA(A)R, Beta1 in a human cell line mix using a 1:1000 dilution of the antibody Mouse IgG1 S96-55 Purified Hu, Ms, Rt C, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GABRB1 antibody

  Rabbit Polyclonal GABA-RB Antibody  
GABRB1 Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABRB1 antibody

  Rabbit Polyclonal anti-GABRB1 antibody  
GABRB1 Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

GABRB1 antibody

  Rabbit Polyclonal Anti-GABRB1 Antibody  
WB Suggested Anti-GABRB1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Small Intestine Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

GABRB1 antibody

  Rabbit Polyclonal Anti-GABRB1 Antibody  
Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: Human fetal brain tissue, Primary antibody: (GABRB1 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABRB1 antibody

Immunohistochemistry (IHC) analysis of GABA-RB antibody (Cat.-No.: AP06129PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GABRB1 antibody

Figure 1. Western blot analysis of extracts from PC12 cells using GABRB1 antibody AP08059PU (Lane 1 and 2). Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €320.00
  Acris Antibodies GmbH

GABRB1 antibody

Figure 1. Western blot analysis of extracts from PC12 cells using GABRB1 antibody AP08059PU (Lane 1 and 2). Rabbit Aff - Purified Hu, Ms, Rt WB
50 µl / €240.00
  Acris Antibodies GmbH

GABRB1 (1-226) antibody

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu P, WB
50 µl / €470.00
  Acris Antibodies GmbH

GABRB1 pSer434 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using GABA-RB (Phospho-Ser434) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

GABRB1 pSer434 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using GABA-RB (Phospho-Ser434) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

GABRB1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GABA-RB (Ab-434) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
50 µg / €230.00
  Assay Biotech

GABRB1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GABA-RB (Ab-434) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

GABRB1 - human gene knockout kit via CRISPR

GABRB1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GABRB1 - human gene knockout kit via CRISPR

GABRB1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

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