GABRD antibody

Principal name

GABRD antibody

Alternative names for GABRD antibody

GABA A receptor subunit delta, Gamma-aminobutyric acid receptor subunit delta

SwissProt ID

O14764 (Human), P18506 (Rat), P22933 (Mouse)

Gene ID

2563 (GABRD), 14403 (Gabrd), 29689

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunoprecipitation (IP), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of GABRD antibody

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces.
There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inwardrectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2).
The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (3). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (4).

General readings

Emberger,W., et al., (2000) Cytogenet. Cell Genet. 89 (3-4), 281-282

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GABRD (N-term) antibody

  Rabbit Anti-GABAA Receptor d, N-Terminus Antibody  
Western blot of mouse cerebellar lysates from wild type (Control) and δ-knockout (δ-K/O) animals showing specific immunolabeling of the ~52k δ-subunit of the GABAA-R. The labeling was absent from a lysate prepared from δ-knockout animals. Rabbit IgG Aff - Purified Ms, Rt C, IP, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GABRD (15-34) antibody

  Mouse Monoclonal Anti-GABA-A Receptor Delta Antibody  
Western blot analysis of GABA(A)R Delta in rat cell line mix using a 1:1000 dilution of the antibody Mouse IgG2a S151-3 Purified Ms, Rt C, ICC/IF, IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GABRD antibody

  Rabbit Polyclonal Anti-GABA(A) delta Receptor (extracellular)  
Western blot analysis of rat brain (lanes 1, and 4), rat cerebellum (lanes 2 and 5) and mouse brain (lanes 3 and 6): 1-3. Anti-GABA(A) d Receptor (extracellular) antibody , (1:200). 4-6. Anti-GABA(A) d Receptor (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GABRD antibody

  Rabbit Polyclonal Anti-GABRD Antibody  
WB Suggested Anti-GABRD Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

GABRD antibody

  Rabbit Polyclonal Anti-GABRD Antibody  
WB Suggested Anti-GABRD Antibody; Titration: 5.0 ug/ml; Positive Control: Jurkat/HepG2 Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GABRD antibody

Top left: cerebellar lysate immunoblot probed with N151/3 (3 μg/mL).
Top right: hippocampus immunohistochemistry with N151/3 (5 μg/mL).
Bottom: cultured rat hippocampal neuron surface (S, left) and total (T, right) protein immunofluorescence staining (green) with N151/3 (2 μg/mL).
Data courtesy of Suchitra Joshi and Jaideep Kapur, University of Virginia. Mouse IgG2a N151/3 Supernatant Ms, Rt ICC/IF, WB
5 ml / €460.00
  Antibodies Incorporated

NeuroMab

GABRD antibody

Top left: cerebellar lysate immunoblot probed with N151/3 (3 μg/mL).
Top right: hippocampus immunohistochemistry with N151/3 (5 μg/mL).
Bottom: cultured rat hippocampal neuron surface (S, left) and total (T, right) protein immunofluorescence staining (green) with N151/3 (2 μg/mL).
Data courtesy of Suchitra Joshi and Jaideep Kapur, University of Virginia. Mouse IgG2a N151/3 Purified Ms, Rt ICC/IF, WB
0.1 ml / €540.00
  Antibodies Incorporated

NeuroMab

GABRD (N-term) antibody

GABRD Rabbit IgG Purified Ms, Rt C, IP, WB
0.1 ml / €500.00
  Acris Antibodies GmbH

GABRD antibody

Western blot (WB) analysis of GABAA Rδ antibody (Cat.-No.: AP21176PU-N) in extracts from HT-29 cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GABRD antibody

Western blot analysis of extracts from LOVO/HT-29 cells, using GABRD Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

GABRD antibody

Western blot analysis of extracts from LOVO/HT-29 cells, using GABRD Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

GABRD (15-34) antibody

GABRD Mouse IgG2a Supernatant Ms, Rt C, ICC/IF, WB
0.1 ml / €440.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

GABRD - human gene knockout kit via CRISPR

GABRD - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GABRD - human gene knockout kit via CRISPR

GABRD - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GABRD - human gene knockout kit via CRISPR

GABRD - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GABRD - human gene knockout kit via CRISPR

GABRD - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gabrd - mouse gene knockout kit via CRISPR

Gabrd - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Gabrd - mouse gene knockout kit via CRISPR

Gabrd - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gabrd - mouse gene knockout kit via CRISPR

Gabrd - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, GABRD (mGFP-tagged) - Human gamma-aminobutyric acid (GABA) A receptor, delta (GABRD), 200 uL, >10^7 TU/mL

Lenti ORF particles, GABRD (mGFP-tagged) - Human gamma-aminobutyric acid (GABA) A receptor, delta (GABRD), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

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