GABRQ antibody

Principal name

GABRQ antibody

Alternative names for GABRQ antibody

GABA A receptor subunit theta, Gamma-aminobutyric acid receptor subunit theta

SwissProt ID

Q9JLF1 (Mouse), Q9UN88 (Human)

Gene ID

55879 (GABRQ), 57249 (Gabrq)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of GABRQ antibody

The A-type receptors for ?-aminobutyric acid (GABA(A)) mediate the majority of fast inhibitory transmission in the mammalian central nervous system. Many clinically important drugs including benzodiazepines, barbiturates and general anesthetics act as positive allosteric modulators of this receptor. GABA(A) receptors are pentameric ligand-gated ion-channels, composed of subunits from many subunit classes: a1-a6, Ã?1-Ã?4, ?1-?4, d, e , ?, p and ?1-?3. The arrangement of subunits around the channel is probably ?Ã?aÃ?a counter-clockwise when viewed from the extracellular space, e and p subunits can replace the ? and d subunit within the pentamer, whereas the ? subunit could replace a Ã? subunit.The localized expression of this subunit is consistent with the fact that all GABA(A) receptor subunit genes have distinct expression patterns in the brain. The ? subunit has been reported to be strongly expressed in the striatum and has been localized to the locus ceruleus.Impairment of the ?-aminobutyric acid (GABA) sigling system is believed to partially account for behavioral and cognitive deficits associated with schizophrenia and mood disorders. Reduction of GABA(A) mediated sigl transmission has also been associated with anxiety, panic, impaired learning and memory.

General readings

Sinkkonen,S.T., et al., (2000) J. Neurosci. 20 (10), 3588-3595

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GABRQ antibody

Western blot analysis of rat brain membrane (lanes 1 and 4), mouse brain membrane (lanes 2 and 5) and CCF-STGI cell lysate (lanes 3 and 6): 1-3. Anti-GABA(A) ? Receptor (extracellular) antibody, (1:500). 4-6. Anti-GABA(A) ? Receptor (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GABRQ antibody

WB Suggested Anti-GABRQ Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

GABRQ antibody

GABRQ Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

GABRQ antibody

Human Jurkat; WB Suggested Anti-GABRQ Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:12500. Positive Control: Jurkat cell lysate; GABRQ antibody - N-terminal region (ARP35283_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

GABRQ antibody

GABRQ Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

GABRQ antibody

Immunohistochemistry-Paraffin: GABRQ Antibody [NBP1-80689] - Immunohistochemical staining of human duodenum shows moderate nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

GABRQ overexpression lysate

GABRQ overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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