GABRR2 antibody

Principal name

GABRR2 antibody

Alternative names for GABRR2 antibody

GABA A receptor subunit rho-2, Gamma-aminobutyric acid receptor subunit rho-2

SwissProt ID

P28476 (Human), P47742 (Rat), P56476 (Mouse), Q0II76 (Bovin)

Gene ID

2570 (GABRR2), 29695 (Gabrr2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Xen (Xenopus), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of GABRR2 antibody

?-Aminobutyric acid (GABA) is the most abundant inhibitory neurotransmitter. It is involved in roughly 40% of the inhibitory sypses.GABA acts through two receptors, GABA(A) and GABA(B). To date, nineteen different GABA(A) subunits have been identified and divided in eight subunits: a (1-6), Ã? (1-3), ? (1-3), d, e, ? (1-3), ? and p. For some of the subunits, altertive splicing further increases the number of existing receptor types. They all have extracellular N- and C-termini and four transmembrane domains.Three r subunits have been detected: GABA(A) ?1, GABA(A) ?2 and GABA(A) ?3. Like all GABA(A) receptors the ? subunits also assemble into a pentameric structure forming a Cl- channel. However, in contrast to all other GABA(A) subunits they mostly form homomeric entities. The GABA(A) ? subunits display different pharmacological characteristics and were therefore once referred to GABA(C) receptors. GABA(A) and GABA(B) respectively respond to bicuculline and baclofen, whereas ? subunits are insensitive to either drug. In addition, ? subunits also display different electrophysiological properties, and are significantly more sensitive to GABA.r subunits are highly expressed in the reti and it was believed that they are only expressed in that area. They are however, also expressed in central and peripheral nervous systems, as well as in the gastrointestil and cardiovascular systems.

General readings

Cavalleri,G.L., (2007) Lancet Neurol 6 (11), 970-980

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GABRR2 antibody

WB Suggested Anti-GABRR2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

GABRR2 antibody

Human 293T; Host: Rabbit. Target Name: HIRIP3 . Sample Tissue: 293T . Antibody Dilution: 1.0ug/ml. GABRR2 is supported by BioGPS gene expression data to be expressed in HEK293T.; GABRR2 antibody - middle region (ARP35060_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

GABRR2 antibody

Western blot analysis of rat eye lysate: 1. Anti-GABA(A) ?2 (extracellular) antibody, (1:200). 2. Anti-GABA(A) ?2 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GABRR2 antibody

GABRR2 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

GABRR2 antibody

Western Blot: GABRR2 Antibody [NBP1-80061] Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt, Xen, Ze WB
50 µg / €440.00
  Novus Biologicals Inc.

GABRR2 antibody

Immunohistochemistry-Paraffin: GABRR2 Antibody [NBP1-86451] Immunohistochemical staining of human seminal vesicle shows cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

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