GALR2 antibody

Principal name

GALR2 antibody

Alternative names for GALR2 antibody

GALR-2, GALNR2, GAL2-R, Galanin receptor type 2

SwissProt ID

O08726 (Rat), O43603 (Human), O88854 (Mouse)

Gene ID

8811 (GALR2), 14428 (Galr2), 29234

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine)

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of GALR2 antibody

Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30 amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7 transmembrane family of G protein coupled receptors. GALR2 interacts with the N terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.GalR2 expression has been documented widely in the brain and in peripheral tissues including small intestine, heart, kidney, and liver. Localization data from rat CNS indicate high levels of expression in dorsal root ganglia, amygdala and Purkinje neurons.

General readings

Berger A, Tuechler C, Almer D, Kogner P, Ratschek M, Kerbl R, Iismaa TP, Jones N, Sperl W, Kofler B.
Elevated expression of galanin receptors in childhood neuroblastic tumors.
Neuroendocrinology. 2002 Feb;75(2):130-8.
PMID: 11867941

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GALR2 antibody

Western blot analysis of GALR2 antibody Cat.-No AP01317PU-N in RAW264.7 whole cell lysate at 1/500 dilution. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GALR2 (C-term) antibody

  GALR2 Rabbit Polyclonal (C-Terminus) Antibody  
Anti-GALR2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

GALR2 antibody

  GALR2 Rabbit Polyclonal (Transmembrane Domain) Antibody  
Anti-GALR2 / Galanin Receptor 2 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

GALR2 antibody

  Goat Polyclonal Antibody against GALR2  
TA303179 (0.3µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GALR2 antibody

  Rabbit Polyclonal antibody to Galanin Receptor 2 (galanin receptor 2)  
Sample(30 ug whole cell lysate). A:293T. B:H1299. 10% SDS PAGE. TA308347 diluted at 1:1000 Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GALR2 antibody

  Rabbit polyclonal antibody to galanin receptor 2 (galanin receptor 2)  
Sample(30 ug of whole cell lysate). A:A431. 12% SDS PAGE. TA308348 diluted at 1:500 Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GALR2 antibody

  Rabbit Polyclonal Anti-Galanin Receptor Type 2  
Western blot analysis of rat hippocampus, DRG (lanes 2 and 5), brain (lanes 3 and 6), mouse brain (lanes 7 and 9) and human prostate carcinoma LNCaP cell lysates: 1, 2, 3, 7, 8. Anti-Galanin Receptor Type 2 antibody, (1:200). 4, 5, 6, 9, 10. Anti-Galanin Receptor Type 2 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GALR2 antibody

Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu P, WB
50 µl / €470.00
  Acris Antibodies GmbH

GALR2 antibody

Western blot analysis of extracts from RAW264.7 cells, using GALR2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

GALR2 antibody

Western blot analysis of extracts from RAW264.7 cells, using GALR2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

GALR2 - human gene knockout kit via CRISPR

GALR2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GALR2 - human gene knockout kit via CRISPR

GALR2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GALR2 - human gene knockout kit via CRISPR

GALR2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GALR2 - human gene knockout kit via CRISPR

GALR2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Galr2 - mouse gene knockout kit via CRISPR

Galr2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Galr2 - mouse gene knockout kit via CRISPR

Galr2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Galr2 - mouse gene knockout kit via CRISPR

Galr2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

GALR2 overexpression lysate

GALR2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, GALR2 (mGFP-tagged) - Human galanin receptor 2 (GALR2), 200 uL, >10^7 TU/mL

Lenti ORF particles, GALR2 (mGFP-tagged) - Human galanin receptor 2 (GALR2), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, GALR2 (Myc-DDK tagged) - Human galanin receptor 2 (GALR2) , 200 uL, >10^7 TU/mL

Lenti ORF particles, GALR2 (Myc-DDK tagged) - Human galanin receptor 2 (GALR2) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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