Gamma-crystallin A / CRYGA antibody

Principal name

Gamma-crystallin A / CRYGA antibody

Alternative names for Gamma-crystallin A / CRYGA antibody

CRYG1, Gamma-A-crystallin, Gamma-crystallin 5

Gene ID

1418 (CRYGA)

Available reactivities

Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat), Ze (Zebrafish)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB)

Background of Gamma-crystallin A / CRYGA antibody

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-termil extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and termil extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Gamma-crystallin A / CRYGA antibody

WB Suggested Anti-CRYGA Antibody; Titration: 1.0 ug/ml; Positive Control: HCT15 Whole Cell Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Gamma-crystallin A / CRYGA

Gamma-crystallin A / CRYGA Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

CRYGA overexpression lysate

CRYGA overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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