Gamma-glutamyl hydrolase / GGH antibody

Principal name

Gamma-glutamyl hydrolase / GGH antibody

Alternative names for Gamma-glutamyl hydrolase / GGH antibody

Conjugase, GH, Gamma-Glu-X carboxypeptidase

SwissProt ID

A7YWG4 (Bovin), Q62867 (Rat), Q92820 (Human), Q9Z0L8 (Mouse)

Gene ID

8836 (GGH)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Chicken

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of Gamma-glutamyl hydrolase / GGH antibody

GGH is a 318 amino acid protein that is secreted into the extracellular space and is also localized to both the lysosome and the melanosome. Functioning as a hydrolase, GGH contains one gamma-glutamyl hydrolase domain through which it catalyzes the hydrolysis of polyglutamate sidechains from pteroylpolyglutamates, specifically hydrolyzing gamma-glutamyl bonds. Via its catalytic activity, GGH may play a role in the bioavailability and metabolic activity of pteroylpolyglutamates. Polymorphisms in the gene encoding GGH are associated with rheumatoid arthritis, inflammatory bowel disease and various cancers. The gene encoding GGH maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.

General readings

Adjei, A.A., et al. J Thorac Oncol 5(9):1346-1353(2010)
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Organista-Nava, J., et al. Leuk. Res. 34(6):728-732(2010)
Figueiredo, J.C., et al. Cancer Causes Control 21(4):597-608(2010)
Dervieux, T., et al. Pharmacogenet. Genomics (2009) In press.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Gamma-glutamyl hydrolase / GGH antibody

Western blot analysis of extracts from RAW264.7 cells, using GGH antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Gamma-glutamyl hydrolase / GGH antibody

Immunohistochemical staining of human small intestine shows cytoplasmic positivity in glandular cells.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only. Rabbit IgG Purified Hu E, ICC/IF, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

Gamma-glutamyl hydrolase / GGH antibody

Western blot (WB) analysis of GGH antibody (Cat.-No.: AP21177PU-N) in extracts from RAW264.7 cells. Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Gamma-glutamyl hydrolase / GGH (C-term) antibody

Formalin fixed and paraffin embedded human liver tissue reacted with GGH Antibody (C-term) Cat.-No AP51829PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu ICC/IF, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Gamma-glutamyl hydrolase / GGH (N-term) antibody

Formalin fixed and paraffin embedded human liver tissue reacted with GGH Antibody (N-term) Cat.-No AP51830PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Gamma-glutamyl hydrolase / GGH antibody

Western blot analysis of extracts from RAW264.7 cells, using GGH Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

Gamma-glutamyl hydrolase / GGH antibody

Western blot analysis of extracts from RAW264.7 cells, using GGH Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

Gamma-glutamyl hydrolase / GGH antibody

ELISA: gamma-glutamyl hydrolase Antibody [28150002] Rabbit Hu E, P, WB
50 µg / €440.00
  Novus Biologicals Inc.

Gamma-glutamyl hydrolase / GGH antibody

Gamma-glutamyl hydrolase / GGH Rabbit Aff - Purified Hu WB
0.1 mg / €420.00
  Novus Biologicals Inc.

Gamma-glutamyl hydrolase / GGH antibody

Gamma-glutamyl hydrolase / GGH Rabbit IgG Aff - Purified Hu E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Gamma-glutamyl hydrolase / GGH antibody

Gamma-glutamyl hydrolase / GGH Rabbit IgG Aff - Purified Hu E, WB
50 µg / €290.00
  Novus Biologicals Inc.

Gamma-glutamyl hydrolase / GGH antibody

Immunohistochemistry-Paraffin: Glutamyl hydrolase gamma Antibody [NBP1-90927] - Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Gamma-glutamyl hydrolase / GGH

Gamma-glutamyl hydrolase / GGH Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Gamma-glutamyl hydrolase / GGH (25-318, His-tag)

Gamma-glutamyl hydrolase / GGH Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

Gamma-glutamyl hydrolase / GGH (25-318, His-tag)

Gamma-glutamyl hydrolase / GGH Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Gamma-glutamyl hydrolase / GGH

Gamma-glutamyl hydrolase / GGH Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Gamma-glutamyl hydrolase / GGH

Gamma-glutamyl hydrolase / GGH Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

GGH overexpression lysate

GGH overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

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