GAT1 / SLC6A1 antibody

Principal name

GAT1 / SLC6A1 antibody

Alternative names for GAT1 / SLC6A1 antibody

GABATR, GABT1, GAT-1, GABA transporter 1, Sodium- and chloride-dependent GABA transporter 1, Solute carrier family 6 member 1

SwissProt ID

P23978 (Rat), P30531 (Human), P31648 (Mouse)

Gene ID

79212 (Slc6a1), 6529 (SLC6A1)

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Mky (Monkey), Por (Porcine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Enzyme Immunoassay (E), Immunoprecipitation (IP)

Background of GAT1 / SLC6A1 antibody

?-aminobutiric acid (GABA) is the major inhibitory neurotransmitter in the mammalian central nervous system. Transmission via GABA can be halted by its reuptake through GABA transporters (GATs). These membrane proteins belong to the super family of slc6 genes which encode transporters responsible for the uptake of dopamine, serotonin, norepinephrine, glycine and GABA in a +-dependent manner. To date, four GATs have been identified: GAT-1, GAT-2, GAT-3 and BGT-1. Like all members of the slc6 family, they have twelve transmembrane domains and short intracellular N- and C-termini. GATs couple the transport of one GABA molecule to 2+ ions and one Cl- ion3. GAT-1 activity can be regulated at the level of its plasma membrane expression which is in part regulated by its trafficking via phosphorylation of residues in intracellular loops. GAT-1 expression is restricted to the central nervous system, specifically to axon termils, in the neocortex and in some astrocytic processes. GAT-1 may be implicated in various psychological and neurological disorders such as schizophrenia, epilepsy and cerebral ischemia1.

General readings

Minelli A, Brecha NC, Karschin C, DeBiasi S, Conti F (1995) GAT-1, a high-affinity GABA plasma membrana transporter, is localizad to neurons and astroglia int he cerebral cortex. J. Neurosci. 15(11):7734-7746.
Zhao WJ, Ma YH, Fei J, Mei ZT, Guo LH (2003) Increase in drug-induced seizure susceptibility of transgenic mice overexpressing GABA transporter 1. Acta Pharmacol. Sin. 24(10):991-5.

18 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GAT1 / SLC6A1 (C-term) antibody

Western blot of rat hippocampal homogenate showing specific immunolabeling of  the~ 67k GAT-1 protein. Rabbit IgG Aff - Purified Ms, Rt C, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GAT1 / SLC6A1 antibody

Western blot analysis of extracts from K562 cells, HeLa cells and 3T3 cells, using SLC6A1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GAT1 / SLC6A1 antibody

Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) brain lysates: 1, 2. Anti-GABA Transporter 1 (GAT-1) (extracellular) antibody, (1:200). 3, 4. Anti-GABA Transporter 1 (GAT-1) (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GAT1 / SLC6A1 antibody

WB Suggested Anti-SLC6A1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

GAT1 / SLC6A1 antibody

WB Suggested Anti-SLC6A1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Liver Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

GAT1 / SLC6A1 antibody

GAT1 / SLC6A1 Rabbit Aff - Purified Rt C, E, WB
25 µg / €430.00
  Acris Antibodies GmbH

GAT1 / SLC6A1 antibody

Olfactory receptor neurons stained in immunohistochemistry with CRMP1 antibody. Rabbit Serum Rt C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

GAT1 / SLC6A1 antibody

GAT1 / SLC6A1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

GAT1 / SLC6A1 antibody

GAT1 / SLC6A1 Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

GAT1 / SLC6A1 antibody

Western blot analysis of GAT1 expression in SHSY5Y (A); NIH3T3 (B); rat brain (C) whole cell lysates. Rabbit Aff - Purified Bov, Can, Hu, Mky, Ms, Por, Rt IP, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

GAT1 / SLC6A1 antibody

Western blot analysis of GAT1 expression in SHSY5Y (A); NIH3T3 (B); rat brain (C) whole cell lysates. Rabbit Aff - Purified Bov, Can, Hu, Mky, Ms, Por, Rt IP, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

GAT1 / SLC6A1 antibody

Western blot analysis of GAT1 expression in SHSY5Y (A); NIH3T3 (B); rat brain (C) whole cell lysates. Rabbit Aff - Purified Bov, Can, Hu, Mky, Ms, Por, Rt IP, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

GAT1 / SLC6A1 antibody

Western blot analysis of GAT1 expression in mouse brain (A); rat brain (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

GAT1 / SLC6A1 antibody

Western blot analysis of GAT1 expression in mouse brain (A); rat brain (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

GAT1 / SLC6A1 antibody

Western blot analysis of GAT1 expression in mouse brain (A); rat brain (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

GAT1 / SLC6A1 antibody

Western Blot: GABA Transporter 1 Antibody [NB100-61097] - Rat hippocampal homogenate showing specific immunolabeling of the~ 67k GAT-1 protein. Rabbit IgG Aff - Purified Rt P, WB
0.1 ml / €380.00
  Novus Biologicals Inc.

GAT1 / SLC6A1 antibody

Western Blot: GABA Transporter 1 Antibody [NBP1-59878] - This Anti-SLC6A1 antibody was used in Western Blot of Fetal Liver tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
50 µg / €440.00
  Novus Biologicals Inc.

GAT1 / SLC6A1 antibody

Immunohistochemistry-Paraffin: GABA Transporter 1 Antibody [NBP1-89802] - Immunohistochemical staining of human small intestine shows strong cytoplasmic positivity, with a granular pattern, in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

18 Item(s)

per page
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