GCAP1 / GUCA1A antibody

Principal name

GCAP1 / GUCA1A antibody

Alternative names for GCAP1 / GUCA1A antibody

Guanylyl cyclase-activating protein 1, GUCA1, C6orf131, Guanylate cyclase activator 1A

SwissProt ID

P43080 (Human), P43081 (Mouse), P46065 (Bovin), P79880 (Chick)

Gene ID

2978 (GUCA1A)

Available reactivities

Bov (Bovine), Hu (Human), Prim (Primate), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of GCAP1 / GUCA1A antibody

This gene plays a role in the recovery of retinal photoreceptors from photobleaching. In the recovery phase, the phototransduction messeneger cGMP is replenished by retinal guanylyl cyclase-1 (GC1). GC1 is activated by decreasing Ca(2+) concentrations following photobleaching. The protein encoded by this gene, guanylyl cyclase activating protein 1 (GCAP1), mediates the sensitivity of GC1 to Ca(2+) concentrations. GCAP1 promotes activity of GC1 at low Ca(2+) concentrations and inhibits GC1 activity at high Ca(2+) concentrations. Mutations in this gene cause autosomal dominant cone dystrophy (COD3); a disease characterized by reduced visual acuity associated with progressive loss of color vision. Mutations in this gene prohibit the inactivation of RetGC1 at high Ca(2+) concentrations; causing the constitutive activation of RetGC1 and, presumably, increased cell death. This gene is expressed in retina and spermatagonia. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

12 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GCAP1 / GUCA1A antibody

WB Suggested Anti-GUCA1A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human kidney Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

GCAP1 / GUCA1A (C-term) antibody

Formalin-fixed and paraffin-embedded human breast carcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GCAP1 / GUCA1A antibody

GCAP1 / GUCA1A Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

GCAP1 / GUCA1A antibody

Western blot analysis of GUCA1A over-expressed 293 cell line, cotransfected with GUCA1A Validated Chimera RNAi ( Cat # H00002978-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with GUCA1A monoclonal antibody (M04), clone 2F7 (Cat # H00002978-M04 ). GAPDH ( 36.1 kDa ) used as specificity and loading control. Mouse IgG2b 2F7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GCAP1 / GUCA1A antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with GUCA1A polyclonal antibody ( Cat # PAB3612 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

GCAP1 / GUCA1A antibody

Human kidney; WB Suggested Anti-GUCA1A Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human kidney; GUCA1A antibody - N-terminal region (ARP54309_P050) in Human kidney cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

GCAP1 / GUCA1A antibody

Western Blot: GCAP1 Antibody [NBP1-54868] - This Anti-GUCA1A antibody was used in Western Blot of Fetal Kidney tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GCAP1 / GUCA1A

GCAP1 / GUCA1A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

GCAP1 / GUCA1A

GCAP1 / GUCA1A Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

GCAP1 / GUCA1A

GCAP1 / GUCA1A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

GCAP1 / GUCA1A

GCAP1 / GUCA1A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

GUCA1A overexpression lysate

GUCA1A overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

12 Item(s)

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