GCAP2 / GUCA1B antibody

Principal name

GCAP2 / GUCA1B antibody

Alternative names for GCAP2 / GUCA1B antibody

Guanylyl cyclase-activating protein 2, Guanylate cyclase activator 1B

SwissProt ID

P51177 (Bovin), P79881 (Chick), Q8VBV8 (Mouse), Q9UMX6 (Human)

Gene ID

2979 (GUCA1B)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of GCAP2 / GUCA1B antibody

The intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating protein (GCAP1). GCAPs are calcium-binding proteins belonging to the calmodulin superfamily. GCAP1 is a calcium-binding protein that stimulates synthesis of cGMP in photoreceptors. GCAP1 is present in rod and cone photoreceptor outer segments where phototransduction occurs. In contrast to other calcium-binding proteins from the calmodulin superfamily, the calcium-free form of GCAP1 stimulates the effector enzyme. By molecular cloning of human and mouse GCAP cDNA, the known mammalian GCAPs are found to be more than 90% similar, consisting of 201 to 205 amino acids and containing three identically conserved calcium-binding sites. A related protein, GCAP2, is detectable only in the retina and results from a gene duplication event. The genes which encode GCAP1 and GCAP2 map to human chromosome 6p21.1.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GCAP2 / GUCA1B antibody

WB Suggested Anti-GUCA1B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: U937 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

GCAP2 / GUCA1B antibody

GCAP2 / GUCA1B Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

GCAP2 / GUCA1B antibody

GCAP2 / GUCA1B Mouse IgG2b 5E7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GCAP2 / GUCA1B (N-term) antibody

Human U937; WB Suggested Anti-GUCA1B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: U937 cell lysate; GUCA1B antibody - N-terminal region (ARP59766_P050) in Human U937 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

GCAP2 / GUCA1B antibody

Western Blot: GCAP 2 Antibody (A1) [NB120-5422] - Figure 1 illustrates Western blot detection of GCAP-2 on bovine rod outer segment lysate using NB120-5422. Mouse IgG2a A1 Purified Bov E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

GCAP2 / GUCA1B antibody

GCAP2 / GUCA1B Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

GCAP2 / GUCA1B antibody

Immunohistochemistry-Paraffin: GCAP2 Antibody [NBP1-89789] Immunohistochemical staining of human duodenum shows distinct positivity in goblet cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GCAP2 / GUCA1B (N-term HIS tag)

GCAP2 / GUCA1B Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

GCAP2 / GUCA1B

GCAP2 / GUCA1B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

GCAP2 / GUCA1B

GCAP2 / GUCA1B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

10 Item(s)

per page
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