GCAP3 / GUCA1C antibody

Principal name

GCAP3 / GUCA1C antibody

Alternative names for GCAP3 / GUCA1C antibody

Guanylyl cyclase-activating protein 3, Guanylate cyclase activator 1C

SwissProt ID

O95843 (Human)

Gene ID

9626 (GUCA1C)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Paraffin Sections (P)

Background of GCAP3 / GUCA1C antibody

The intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating proteins (GCAP). GCAPs are calcium-binding proteins belonging to the calmodulin superfamily and are specifically expressed in retina. GCAP3 (Guanylyl cyclase-activating protein 3), also known as GUCA1C (Guanylate cyclase activator 1C), is a 209 amino acid EF-hand calcium binding protein that is activated by the decrease in calcium from the absorption of light by rhodopsin. Activation of GCAP3 leads to stimulation of guanylate cyclase 1 and 2 (GC1 and GC2), which increases cGMP concentration. Calcium sensitive regulation of GC is essential in recovery of the rod receptor dark state following light exposure. There are two isoforms of GCAP3 that are produced as a result of alternative splicing events.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GCAP3 / GUCA1C antibody

GCAP3 / GUCA1C Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

GCAP3 / GUCA1C antibody

Immunoprecipitation of GUCA1C transfected lysate using anti-GUCA1C MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with GUCA1C MaxPab mouse polyclonal antibody (B01) (H00009626-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

GCAP3 / GUCA1C antibody

Western Blot analysis of GUCA1C expression in transfected 293T cell line (H00009626-T02) by GUCA1C MaxPab polyclonal antibody.

Lane 1: GUCA1C transfected lysate(23.80 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

GCAP3 / GUCA1C antibody

GCAP3 / GUCA1C Mouse IgG2a 3F10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GCAP3 / GUCA1C antibody

Immunohistochemistry-Paraffin: GCAP3 Antibody [NBP1-91930] Immunohistochemical staining of human colon shows moderate membranous and cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GCAP3 / GUCA1C (full length, N-term HIS tag)

GCAP3 / GUCA1C Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

GCAP3 / GUCA1C

GCAP3 / GUCA1C Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

GCAP3 / GUCA1C

GCAP3 / GUCA1C Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

GCAP3 / GUCA1C

GCAP3 / GUCA1C Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

GCAP3 / GUCA1C

GCAP3 / GUCA1C Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

GUCA1C (Human) IP-WB Antibody Pair

GUCA1C (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

GUCA1C 293T Cell Transient Overexpression Lysate(Denatured)

GUCA1C 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

GUCA1C overexpression lysate

GUCA1C overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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