GCKR antibody

Principal name

GCKR antibody

Alternative names for GCKR antibody

GCKR, Glucokinase regulatory protein, Glucokinase regulator

SwissProt ID

Q07071 (Rat), Q14397 (Human), Q91754 (Xenla), Q91X44 (Mouse)

Gene ID

2646 (GCKR), 4342646 (Os07g0195400)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ye (Yeast)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of GCKR antibody

Glucokinase (also designated hexokinase IV or GCK) plays a key role in the regulation of glucose-induced insulin secretion. GCK is expressed in pancreatic beta cells, where it functions as a glucose sensor, determining the “set point” for insulin secretion. GCK is also expressed in the liver, where it catalyzes the first step in the disposal of glucose. A lack of glucokinase activity leads to reduced insulin secretion and hyperglycemia and has been implicated as a cause for maturity onset diabetes of the youth (MODY). Heterozygous point mutations in the gene encoding GCK have been detected in individuals suffering from MODY. GCK is regulated by GCKR (glucokinase regulatory protein). GCKR is a 68 kDa protein which is expressed in pancreatic beta cells and in the liver.

General readings

Kathiresan S, Melander O, Guiducci C, Surti A, Burtt NP, Rieder MJ, Cooper GM, Roos C, Voight BF, Havulinna AS, Wahlstrand B, Hedner T, Corella D, Tai ES, Ordovas JM, Berglund G, Vartiainen E, Jousilahti P, Hedblad B, Taskinen MR, Newton-Cheh C, Salomaa V, Peltonen L, Groop L, Altshuler DM, Orho-Melander M.
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.
Nat Genet. 2008 Feb;40(2):189-97. Epub 2008 Jan 13.
PMID: 18193044

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GCKR antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-GCKR mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502152) Mouse IgG1 OTI1E7 Purified Hu ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

GCKR antibody

TA305630 (0.1ug/ml) staining of Rat Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GCKR antibody

Western blot analysis of extracts from mouse heart cells and rat heart cells, using Glucokinase Regulator antibodyThe lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GCKR antibody

Host: Rabbit; Target Name: Gckr; Sample Tissue: Mouse Brain lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ye WB
50 µg / €325.00
  OriGene Technologies, Inc.

GCKR antibody

Western blot analysis on mouse heart cell lysate using GCKR Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GCKR antibody

Anti-GCKR mouse monoclonal antibody (TA502163) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY GCKR(RC214230). Mouse IgG1 OTI9G7 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

GCKR antibody

Western blot (WB) analysis of GCKR antibody (Cat.-No.: AP06733PU-N) in extracts from PC12 cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GCKR antibody

GCKR Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

GCKR antibody

GCKR polyclonal antibody ( Cat # PAB13669 ) ( 0.1µg/ml ) staining of rat liver lysate ( 35µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Ms, Rt E
0.1 mg / €400.00
  Abnova Taiwan Corp.

GCKR antibody

Western blot analysis of extracts from mouse heart/rat heart cells, using Glucokinase Regulator Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

GCKR antibody

Western blot analysis of extracts from mouse heart/rat heart cells, using Glucokinase Regulator Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

GCKR antibody

Western blot analysis of GCKR expression in A431 (A); mouse heart (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

GCKR antibody

Western blot analysis of GCKR expression in A431 (A); mouse heart (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

GCKR antibody

Western blot analysis of GCKR expression in A431 (A); mouse heart (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

GCKR antibody

GCKR Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €420.00
  Novus Biologicals Inc.

GCKR antibody

Western Blot: GCKR Antibody[NBP1-28910]-(0.1ug/ml) staining of Rat Liver lysate (35ug protein in RIPA buffer). Goat IgG Aff - Purified Ms, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GCKR

GCKR Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

17 Item(s)

per page
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