Gelsolin antibody
Principal name
Gelsolin antibody
Alternative names for Gelsolin antibody
Brevin, AGEL, GSN, Actin-depolymerizing factor
SwissProt ID
O93510 (Chick), P06396 (Human), P13020 (Mouse), P20305 (Pig), Q28372 (Horse), Q3SX14 (Bovin), Q68FP1 (Rat)
Ncbi ID
NP_000168.1, 9606, NP_000168, NM_000177, NM_146120, NM_001004080, NM_198252, NM_001127662, NM_001127663, NM_001127664, NM_001127665, NM_001127667, NM_001127666, NP_666232.2
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of Gelsolin antibody
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells.
Defects in GSN are the cause of amyloidosis type 5 (AMYL5) [MIM:105120]; also known as familial amyloidosis Finnish type. AMYL5 is a hereditary generalized amyloidosis due to gelsolin amyloid deposition. It is typically characterized by cranial neuropathy and lattice corneal dystrophy. Most patients have modest involvement of internal organs, but severe systemic disease can develop in some individuals causing peripheral polyneuropathy, amyloid cardiomyopathy, and nephrotic syndrome leading to renal failure.
General readings
Shokouhi,G. Nephrol. Dial. Transplant. 23 (3), 1071 (2008)

















Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
---|---|---|---|---|---|---|---|
AP31939PU-N | Gelsolin (Isoform a) antibody |
||||||
![]() |
Goat | Aff - Purified | Hu | E, WB |
0.1 mg /
€350.00
|
||
Acris Antibodies GmbH | |||||||
Acris recommends this product for Western blotting. |
|||||||
TA303164 | Gelsolin antibody |
||||||
Goat Polyclonal Antibody against GSN | |||||||
![]() |
Goat | Aff - Purified | Can, Hu, Ms, Rt | WB |
0.1 mg /
€360.00
|
||
OriGene Technologies, Inc. | |||||||
TA323717 | Gelsolin antibody |
||||||
Anti-GSN Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
|
OriGene Technologies, Inc. | |||||||
![]() |
|||||||
TA323718 | Gelsolin antibody |
||||||
Anti-GSN Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
|
OriGene Technologies, Inc. | |||||||
![]() |
|||||||
TA327454 | Gelsolin antibody |
||||||
GSN Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 mg /
€335.00
|
|
OriGene Technologies, Inc. | |||||||
![]() |
|||||||
TA336242 | Gelsolin antibody |
||||||
Rabbit Polyclonal Anti-GSN Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Bov, Eq, Hu, Rt, Sh, Ze | ICC/IF, P, WB |
50 µg /
€360.00
|
|
OriGene Technologies, Inc. | |||||||
![]() |
|||||||
AM20623PU-N | Gelsolin antibody |
||||||
![]() |
Mouse | IgG1 | GEL-42 | Purified | Hu, Rb | C, P, WB |
0.1 mg /
€390.00
|
Acris Antibodies GmbH | |||||||
AM31077PU-N | Gelsolin antibody |
||||||
![]() |
Mouse | IgG1 | 3G5 | Purified | Hu | E, IP, P, WB |
50 µg /
€420.00
|
Acris Antibodies GmbH | |||||||
![]() |
|||||||
AP23589PU-N | Gelsolin (161-369) antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu | ICC/IF, P, WB |
50 µl /
€380.00
|
||
Acris Antibodies GmbH | |||||||
![]() |
|||||||
BP492 | Gelsolin antibody |
||||||
![]() |
Sheep | Purified | Bov, Hu, Ms, Por | E |
1 ml /
€370.00
|
||
Acris Antibodies GmbH |
CRISPR
Catalog No. | Species | Donor Vector | |
---|---|---|---|
KN206861 | GSN - human gene knockout kit via CRISPR |
||
![]() |
Human | GFP-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN206861BN | GSN - human gene knockout kit via CRISPR |
||
![]() |
Human | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN307383BN | Gsn - mouse gene knockout kit via CRISPR |
||
![]() |
Mouse | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN307383LP | Gsn - mouse gene knockout kit via CRISPR |
||
![]() |
Mouse | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN307383RB | Gsn - mouse gene knockout kit via CRISPR |
||
![]() |
Mouse | RFP-BSD |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. |
Proteins & Growth Factors
Catalog No. | Species | Pres. | Purity | Source | |
---|---|---|---|---|---|
TP314871 | Gelsolin (transcript variant 1) |
||||
Recombinant protein of human gelsolin (amyloidosis, Finnish type) (GSN), transcript variant 1 | |||||
![]() |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€680.00
|
|
OriGene Technologies, Inc. |
Lysates
Catalog No. | ||
---|---|---|
LY424875 | GSN overexpression lysate |
|
![]() |
0.1 mg /
€295.00
|
|
OriGene Technologies, Inc. |
Human Lenti ORF Particles
Catalog No. | ||
---|---|---|
RC214871L2V | Lenti ORF particles, GSN (mGFP-tagged) - Human gelsolin (GSN), transcript variant 1, 200 uL, >10^7 TU/mL |
|
![]() |
200 µl /
€1,751.00
|
|
OriGene Technologies, Inc. | ||
RC206861L2V | Lenti ORF particles, GSN (mGFP-tagged)-Human gelsolin (GSN), transcript variant 2, 200 uL, >10^7 TU/mL |
|
![]() |
200 µl /
€1,082.00
|
|
OriGene Technologies, Inc. | ||
RC226117L2V | Lenti ORF particles, GSN (mGFP-tagged)-Human gelsolin (GSN), transcript variant 3, 200 uL, >10^7 TU/mL |
|
![]() |
200 µl /
€1,082.00
|
|
OriGene Technologies, Inc. | ||