GEM / KIR antibody

Principal name

GEM / KIR antibody

Alternative names for GEM / KIR antibody

GTP-binding protein GEM, RAS-like protein KIR, GTP-binding mitogen-induced T-cell protein

SwissProt ID

P55040 (Human), P55041 (Mouse)

Gene ID

2669 (GEM), 12669 (Chrm1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Dot blot (Dot), ELISA (detection) (E(detection))

Background of GEM / KIR antibody

Gem belongs to the Rad/Gem/Kir (RGK) subfamily of Ras-related GTPases, which lack typical C-terminal amino acid motifs for isoprenylation. Rad and Gem bind calmodulin in a Ca2+-dependent manner via this C-terminal extension, involving residues 278–297 in human Rad. High intracellular Gem levels, which interact with intact microtubules and microfilaments, promote profound changes in cell morphology. Ectopic Gem expression is sufficient to stimulate cell flattening and neurite extension in N1E-115 and SH-SY5Y neuroblastoma cells, suggesting a role for Gem in cytoskeletal rearrangement and/or morphological differentiation of neurons. Gem was also observed in developing trigeminal nerve ganglia in 12.5 day mouse embryos, demonstrating that Gem expression is a property of normal ganglionic development. The interaction of Gem with beta-subunits regulates Ca2+ channel expression at the cell surface. The human Gem gene maps to chromosome 8q22.1.

General readings

Sano,A., (2005) Trends Cell Biol. 15 (12), 640-643

13 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GEM / KIR antibody

Sample (30 ug of whole cell lysate). A: 293T. 12% SDS PAGE. TA308309 diluted at 1:500. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GEM / KIR (34-46) antibody

(1ug/ml) staining of Human Spleen lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GEM / KIR antibody

GEM / KIR Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

GEM / KIR antibody

Detection limit for recombinant GST tagged GEM is approximately 0.3ng/ml as a capture antibody. Mouse IgG2a 4B12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GEM / KIR antibody

Human OVCAR-3; WB Suggested Anti-GEM Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: OVCAR-3 cell lysate; GEM antibody - N-terminal region (ARP42225_P050) in Human OVCAR-3 cells using Western Blot Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

GEM / KIR antibody

Human skin; Rabbit Anti-GEM Antibody. Catalog Number: ARP42226. Paraffin Embedded Tissue: Human Skin. Cellular Data: Squamous epithelial cells. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; GEM antibody - C-terminal region (ARP42226_T100) in Human skin cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

GEM / KIR antibody

Western Blot: GEM Antibody [NBP1-30962] - Western blot analysis of GEM Antibody on 293T, diluted at 1:500 with 12% SDS PAGE gel. Rabbit IgG Hu Dot, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

GEM / KIR antibody

Immunohistochemistry-Paraffin: GEM Antibody [NBP1-58906] - Human skin squamouse epithelial cells (indicated with arrows). Rabbit Purified Bov, Can, Hu, Ms, Rt P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

GEM / KIR antibody

Immunohistochemistry-Paraffin: GEM Antibody [NBP1-81350] - Immunohistochemical staining of human adrenal gland shows strong nuclear and cytoplasmic positivity in cortical cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GEM / KIR (transcript variant 2)

GEM / KIR Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

GEM / KIR (transcript variant 1)

GEM / KIR Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

GEM / KIR

GEM / KIR Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

GEM / KIR

GEM / KIR Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

13 Item(s)

per page
  • LinkedIn