Gemin-6 antibody

Principal name

Gemin-6 antibody

Alternative names for Gemin-6 antibody

Gem-associated protein 6, GEMIN6, SIP2

SwissProt ID

Q2KHW8 (Bovin), Q8WXD5 (Human), Q9CX53 (Mouse)

Gene ID

79833 (GEMIN6)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), EPair for Elisa (EPair), Paraffin Sections (P)

Background of Gemin-6 antibody

Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (Survival of Motor Neuron) gene. Gemin6, the protein product of human chromosome 2p22.2, associates directly with SMN and is a part of the SMN complex containing Gemin2, Gemin3, Gemin4 and Gemin5 as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies).

General readings

Carissimi,C., et al. (2006) J. Biol. Chem. 281 (48), 37009-37016Pellizzoni,L., et al. (2002) J. Biol. Chem. 277 (9), 7540-7545

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Gemin-6 antibody

Immunofluorescence of purified MaxPab antibody to GEMIN6 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

Gemin-6 antibody

GEMIN6 MaxPab rabbit polyclonal antibody. Western Blot analysis of GEMIN6 expression in human stomach. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Gemin-6 antibody

Detection limit for recombinant GST tagged GEMIN6 is approximately 0.3ng/ml as a capture antibody. Mouse IgG2b 3D2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Gemin-6 antibody

Immunohistochemistry-Paraffin: GEMIN6 Antibody [NBP1-82075] - Immunohistochemical staining of human adrenal gland shows strong cytoplasmic and nuclear positivity in cortical cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Gemin-6

Gemin-6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Gemin-6 (1-167, His-tag)

Gemin-6 Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

Gemin-6 (1-167, His-tag)

Gemin-6 Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Gemin-6

Gemin-6 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Gemin-6

Gemin-6 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

GEMIN6 (Human) Matched Antibody Pair

GEMIN6 (Human) Matched Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

GEMIN6 293T Cell Transient Overexpression Lysate(Denatured)

GEMIN6 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

GEMIN6 overexpression lysate

GEMIN6 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

12 Item(s)

per page
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