GFPT1 / GFAT1 antibody

Principal name

GFPT1 / GFAT1 antibody

Alternative names for GFPT1 / GFAT1 antibody

Hexosephosphate aminotransferase 1, GFAT, GFPT, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1, Glutamine:fructose 6 phosphate amidotransferase 1, D-fructose-6-phosphate amidotransferase 1

SwissProt ID

P47856 (Mouse), P82808 (Rat), Q06210 (Human)

Gene ID

2673 (GFPT1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Can (Canine)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of GFPT1 / GFAT1 antibody

Glutamine:fructose-6-phosphate amidotransferase (GFAT1) is the first and rate-limiting enzyme for the entry of glucose into the hexosamine biosynthesis pathway (HBP) in mammals. GFAT1, a member of the N-terminal nucleophile class of amidotransferases, converts fructose-6-phosphate into N-acetylglucosamine-6-phosphate. Hyperglycemia-induced insulin resistance, a condition in which exposure to high concentrations of glucose and insulin results in insulin resistance, may result from increased glucose metabolism through the HBP. Hypergylcemia-induced insulin resistance is a characteristic feature of type 2 diabetes. Consequently, GFAT1 is a potential therapeutic target in the treatment of type 2 diabetes.

General readings

Selcen,D., et al. (2013) Neurology 81 (4), 370-378 Huh,S.Y., et al. (2012) Muscle Nerve 46 (4), 600-604

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  2. Highly Validated (1)

8 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GFPT1 / GFAT1 (C-term) antibody

Anti-GFPT1 / GFAT antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Aff - Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

GFPT1 / GFAT1 (N-term) antibody

Anti-GFPT1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Aff - Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GFPT1 / GFAT1

GFPT1 / GFAT1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

GFPT1 / GFAT1 (332-699, His-tag)

GFPT1 / GFAT1 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

GFPT1 / GFAT1 (332-699, His-tag)

GFPT1 / GFAT1 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

GFPT1 / GFAT1

GFPT1 / GFAT1 Human
10 µg / €380.00
  Abnova Taiwan Corp.

GFPT1 / GFAT1

GFPT1 / GFAT1 Human
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

GFPT1 overexpression lysate

GFPT1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

8 Item(s)

per page
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