GFRA3 / GDNFR-alpha 3 antibody

Principal name

GFRA3 / GDNFR-alpha 3 antibody

Alternative names for GFRA3 / GDNFR-alpha 3 antibody

GFR-alpha-3, GDNF receptor alpha-3, GDNF family receptor alpha-3

SwissProt ID

O35118 (Mouse), O60609 (Human)

Gene ID

2676 (GFRA3), 14587 (Gfra3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Goat, Chicken, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of GFRA3 / GDNFR-alpha 3 antibody

Members of the glial cell line-derived neurotrophic factor (GDNF) family including GDNF and neurturin (NTN) play essential roles in the control of vertebrate neuron survival and differentiation. A new member of the GDNF family was recently identified and designated persephin. Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphadidylinositol linked protein GFRalpha and Ret receptor tyrosine kinase GFRbeta (2). Following the findings of GFRΑ-1 and -2, a novel receptor in GFRalpha family was identified very recently from human and mouse and designated GFRalpha-3. GFRalpha-3 binds persephin, thus, persephin, GFRalpha-3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function.

General readings

Souza, R.P., et al. J Psychiatr Res 44(11):700-706(2010)
Zhu, D.L., et al. Nan Fang Yi Ke Da Xue Xue Bao 29(3):428-432(2009)
Wang, X., et al. Structure 14(6):1083-1092(2006)
Yang, C., et al. J. Mol. Histol. 37 (1-2), 69-77 (2006)
Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)

18 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GFRA3 / GDNFR-alpha 3 (Center) antibody

Western blot analysis of GFR alpha 3 in crude cell membrane fractions of mouse heart (H), spleen (S), kidney (K), liver (L), and brain (B), respectively, with GFR alpha 3 antibody at 1:500 dilution. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GFRA3 / GDNFR-alpha 3 antibody

Gel: 10%SDS-PAGE, Lysate: 40 µg, Lane 1-2: Human fetal kidney tissue, Human brain tissue, Primary antibody:GFRA3 Antibody at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GFRA3 / GDNFR-alpha 3 antibody

Predicted cell location: Cytoplasm, Cell membrane. Positive control: Human esophagus cancer tissue. Recommended dilution: 1/50-150  The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using GFRA3 antibody at dilution 1/60, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

GFRA3 / GDNFR-alpha 3 (347-360) antibody

Western blot analysis using GFRa-3 antibody on mouse heart (1), spleen (2), kidney (3), liver (4) and brain (5). Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €370.00
  Acris Antibodies GmbH

GFRA3 / GDNFR-alpha 3 antibody

Adrenal: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

GFRA3 / GDNFR-alpha 3 Control Peptide

GFRA3 / GDNFR-alpha 3
50 µg / €160.00
  Acris Antibodies GmbH

GFRA3 / GDNFR-alpha 3 antibody

IF detection of human GFRα-3 expressed in U2OS cells. GFRα-3 was visualized using Chicken polyclonal antibody to human GFRα-3 (dilution 1:3000) and Goat anti-chicken IgY-H&L DyLight 550 (dilution 1:200) as secondary antibody. For nuclear staining DAPI was used. ArrayScan VTI platform (Thermo Scientific) was used for image acquisition (10x objective). Composite picture was generated using pseudocolors green for GFRα-3 specific signal and blue for nuclei. Chicken IgY Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

GFRA3 / GDNFR-alpha 3 (Center) antibody

Western blot analysis of GFRA3 Antibody (Center) Cat.-No AP51825PU-N in HepG2 cell line lysates (35ug/lane).This demonstrates the GFRA3 antibody detected the GFRA3 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GFRA3 / GDNFR-alpha 3 antibody

Immunohistochemical staining of rat dorsal root ganglia using rabbit Gfra3 polyclonal antibody ( Cat # PAB0695 ) . Rabbit Ms, Rt C, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

GFRA3 / GDNFR-alpha 3 antibody

Western blot analysis of Gfra3 in crude cell membrane fractions of murine heart ( 1 ) , spleen ( 2 ) , kidney ( 3 ) , liver ( 4 ) , and brain ( 5 ) , respectively, with Gfra3 polyclonal antibody at 1:500 dilution. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

GFRA3 / GDNFR-alpha 3 antibody

GFRa-3 staining of cryostat sections of 15 d.p.c. mouse embryos. Tissues were stained using anti-goat HRP-DAB (brown) and counterstained with hematoxylin (blue). Goat Aff - Purified Ms C, E, WB
0.1 mg / €450.00
  Neuromics Antibodies

GFRA3 / GDNFR-alpha 3 (347-360) antibody

GFRa-3 staining of Mouse Andrenal Tissue (FFPE) Rabbit IgG Aff - Purified Ms P, WB
50 µg / €460.00
  Neuromics Antibodies

GFRA3 / GDNFR-alpha 3 antibody

Immunohistochemistry-Paraffin: GFR alpha 3 Antibody [NBP1-77035] - Mouse heart tissue with GFR alpha 3 antibody at 10 u/mL._x000d_ Rabbit Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

GFRA3 / GDNFR-alpha 3 antibody

Immunohistochemistry-Paraffin: GFR alpha 3 Antibody [NBP1-89774] - Immunohistochemical staining of human lung shows strong positivity in alveolar cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GFRA3 / GDNFR-alpha 3 (32-374, His-tag)

GFRA3 / GDNFR-alpha 3 Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

GFRA3 / GDNFR-alpha 3 (32-374, His-tag)

GFRA3 / GDNFR-alpha 3 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

GFRA3 / GDNFR-alpha 3

GFRA3 / GDNFR-alpha 3 Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

GFRA3 overexpression lysate

GFRA3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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