GFRA4 / GDNFR-alpha 4 antibody

Principal name

GFRA4 / GDNFR-alpha 4 antibody

Alternative names for GFRA4 / GDNFR-alpha 4 antibody

GFR-alpha-4, Persephin receptor, GDNF receptor alpha-4, GDNF family receptor alpha-4

SwissProt ID

O93512 (Chick), Q9EPI2 (Rat), Q9GZZ7 (Human), Q9GZZ7-2, Q9JJT2 (Mouse)

Gene ID

64096 (GFRA4), 14588 (Gfra4), 66023

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Goat, Chicken, Rat, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of GFRA4 / GDNFR-alpha 4 antibody

The GDNF family ligands (GFLs) belong to the super family of the TGF-Ã?. They belong to the group of cystine-knot protein and function as homodimer1. This family includes glial cell line-derived neurotrophic factor (GDNF), artemin (ARTN), Neurturin (NRTN) and persephin (PSPN).These factors are heavily involved in the development and function of the nervous system (both central and peripheral). In particular GDNF has an important role outside the nervous system where it plays a role in kidney morphogenesis.n general GFLs all sigl through a sigl through the receptor tyrosine kise Ret. Their specificity is implemented by different GDNF family receptor a (GFRa), which act as co-receptors. These extracellular proteins are bound to the plasma membrane via a glycosyl phosphatidyl inositol (GPI) anchor. GFRa1-4 are responsible for the binding of GDNF, NRTN, ARTN, and PSPN respectively and the subsequent activation of Ret. Soluble forms of the receptor by the cleavage of a yet unknown phospholipase or protease can be detected. Also altertive spliced forms of the protein can lead to soluble forms of GFRa receptors.

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GFRA4 / GDNFR-alpha 4 antibody

Predicted cell location: Cytoplasm. Positive control: Human colon and thyroid cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using GFRA4 antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

GFRA4 / GDNFR-alpha 4 antibody

Predicted band size: 32 kDa . Positive control: 293T cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lane1: 293T cell lysate Lysate: 60 ug per lane Primary antibody: 1/600 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GFRA4 / GDNFR-alpha 4 antibody

Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) brain membranes: 1-2. Anti-GDNF Family Receptor α4 (extracellular) antibody , (1:800). 3-4. Anti-GDNF Family Receptor α4 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GFRA4 / GDNFR-alpha 4 antibody

Western blot analysis on HeLa cell lysate using GFRA4 Antibody Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GFRA4 / GDNFR-alpha 4 antibody

Western blot (WB) analysis of GFRα-4 antibody (Cat.-No.: AP01475PU-N) in extracts from HeLa cells. Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GFRA4 / GDNFR-alpha 4 antibody

IF detection of human GFRα-4 expressed in U2OS cells. GFRα-4 was visualized using Chicken polyclonal antibody to human GFRα-4 (dilution 1:2000) and Goat anti-chicken IgY - H&L DyLight 550 (dilution 1:200) as secondary antibody. For nuclear staining DAPI was used. ArrayScan VTI platform (Thermo Scientific) was used for image acquisition (10x objective). Composite picture was generated using pseudocolors green for GFRα-4 specific signal and blue for nuclei. Chicken IgY Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

GFRA4 / GDNFR-alpha 4 antibody

Western blot analysis of extracts from HeLa cells, using GFRA4 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

GFRA4 / GDNFR-alpha 4 antibody

Western blot analysis of extracts from HeLa cells, using GFRA4 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

GFRA4 / GDNFR-alpha 4 (C-term) antibody

Human 721_B; WB Suggested Anti-GFRA4 Antibody. . Titration: 1.0 ug/ml. . Positive Control: 721_B Whole Cell. GFRA4 is supported by BioGPS gene expression data to be expressed in 721_B.; GFRA4 antibody - C-terminal region (ARP61585_P050) in Human 721_B cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

GFRA4 / GDNFR-alpha 4 (C-term) antibody

Human 721_B; WB Suggested Anti-GFRA4 Antibody. . Titration: 1.0 ug/ml. . Positive Control: 721_B Whole Cell. GFRA4 is supported by BioGPS gene expression data to be expressed in 721_B.; GFRA4 antibody - C-terminal region (ARP61586_P050) in Human 721_B cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

GFRA4 / GDNFR-alpha 4 (35-242) antibody

GFRA4 / GDNFR-alpha 4 Goat Aff - Purified Ms C, E, WB
0.1 mg / €450.00
  Neuromics Antibodies

GFRA4 / GDNFR-alpha 4 (35-242) antibody

GFRA4 / GDNFR-alpha 4 Goat Aff - Purified Ms C, E, WB
0.1 mg / €450.00
  Neuromics Antibodies

GFRA4 / GDNFR-alpha 4 antibody

Western Blot: Persephin receptor Antibody [NBP1-00848] - (WB) analysis of GFRa-4 (P178) antibody in extracts from HeLa cells. Rabbit Aff - Purified Hu WB
0.1 mg / €420.00
  Novus Biologicals Inc.

GFRA4 / GDNFR-alpha 4 antibody

GFRA4 / GDNFR-alpha 4 Rabbit IgG Aff - Purified Hu E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

GFRA4 / GDNFR-alpha 4 antibody

GFRA4 / GDNFR-alpha 4 Rabbit IgG Aff - Purified Hu E, WB
50 µg / €290.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

GFRA4 overexpression lysate

GFRA4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

GFRA4 overexpression lysate

GFRA4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

GFRA4 overexpression lysate

GFRA4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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