GGCX antibody

Principal name

GGCX antibody

Alternative names for GGCX antibody

Gamma-glutamyl carboxylase, GC, Vitamin K-dependent gamma-carboxylase, Vitamin K gamma glutamyl carboxylase

SwissProt ID

O88496 (Rat), P38435 (Human), Q07175 (Bovin), Q9QYC7 (Mouse)

Gene ID

2677 (GGCX)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), African clawed frog, Can (Canine), Eq (Equine), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of GGCX antibody

GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP; MIM 112260) and bone matrix protein (MGP; MIM 154870).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Higgins-Gruber, S.L., et al. J. Biol. Chem. 285(41):31502-31508(2010)
King, C.R., et al. Thromb. Haemost. 104(4):750-754(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Ikejiri, M., et al. Int. J. Hematol. 92(2):302-305(2010)
Schelleman, H., et al. Br J Clin Pharmacol 70(3):393-399(2010).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GGCX (C-term) antibody

TA305624 (0.3ug/ml) staining of Human Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Can, Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GGCX antibody

WB Suggested Anti-GGCX Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: MCF7 cell lysate.GGCX is strongly supported by BioGPS gene expression data to be expressed in MCF7 Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

GGCX (Center) antibody

Formalin fixed and paraffin embedded human liver tissue reacted with GGCX Antibody (Center) Cat.-No AP51828PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GGCX antibody

GGCX Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

GGCX antibody

Human Adult Liver; Rabbit Anti-GGCX Antibody . Catalog Number: ARP44340_P050. Formalin Fixed Paraffin Embedded Tissue: Human Adult Liver . Observed Staining: Cytoplasm in hepatocytes, strong signal, wide tissue distribution. Primary Antibody Concentration: 1:100. Secondary Antibody: Donkey anti-Rabbit-Cy3. Secondary Antibody Concentration: 1:200. Magnification: 20X. Exposure Time: 0.5 – 2.0 sec. Protocol located in Reviews and Data.; GGCX antibody - middle region (ARP44340_P050) in Human Adult Liver cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  


GGCX Human
2 µg / €300.00
  Abnova Taiwan Corp.


Catalog No.    

GGCX overexpression lysate

GGCX overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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