GGPP synthetase antibody

Principal name

GGPP synthetase antibody

Alternative names for GGPP synthetase antibody

GGPPSase, GGPS1, Geranylgeranyl pyrophosphate synthetase

SwissProt ID

O95749 (Human), P56966 (Bovin), Q6F596 (Rat), Q9WTN0 (Mouse)

Gene ID

9453 (GGPS1), 14593 (Ggps1), 291211

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), Por (Porcine), Rb (Rabbit), GP (Guinea Pig)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of GGPP synthetase antibody

GGPS1 is a member of the prenyltransferase family and has geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. The protein is an important precursor of carotenoids and geranylated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

General readings

Choi, H.J., et al. Yonsei Med. J. 51(2):231-238(2010)
Raz, T., et al. Blood 110(6):2102-2109(2007)
Miyagi, Y., et al. J. Biochem. 142(3):377-381(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Zhao, Y., et al. Sci. China, C, Life Sci. 43(6):613-622(2000).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GGPP synthetase antibody

  GGPS1 mouse monoclonal antibody, clone OTI3F9 (formerly 3F9)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-GGPS1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501731) Mouse IgG1 OTI3F9 Purified Hu P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

GGPP synthetase antibody

  Rabbit Polyclonal Anti-GGPS1 Antibody  
WB Suggested Anti-GGPS1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: 293T cell lysate.GGPS1 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

GGPP synthetase antibody

  Rabbit Polyclonal Anti-GGPS1 Antibody  
WB Suggested Anti-GGPS1 Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

GGPP synthetase antibody

  GGPS1 mouse monoclonal antibody, clone OTI2E7 (formerly 2E7)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GGPS1 (RC202699, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GGPS1. Mouse IgG2a OTI2E7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

GGPP synthetase antibody

  anti-GGPS1 mouse monoclonal antibody, clone OTI1C6 (formerly 1C6)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GGPS1 (RC202699, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GGPS1. Mouse IgG1 OTI1C6 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

GGPP synthetase (N-term) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with GGPS1 Antibody (N-term)(Cat.#AP12198PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GGPP synthetase (C-term) antibody

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with GGPS1 Antibody (C-term)(Cat#AP12199PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GGPP synthetase (Center) antibody

Western blot analysis of GGPS1 Antibody (Center) (Cat.-No AP51831PU-N in 293 cell line lysates (35ug/lane). This demonstrates the GGPS1 antibody detected the GGPS1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

GGPS1 - human gene knockout kit via CRISPR

GGPS1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GGPS1 - human gene knockout kit via CRISPR

GGPS1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GGPS1 - human gene knockout kit via CRISPR

GGPS1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GGPS1 - human gene knockout kit via CRISPR

GGPS1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ggps1 - mouse gene knockout kit via CRISPR

Ggps1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Ggps1 - mouse gene knockout kit via CRISPR

Ggps1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ggps1 - mouse gene knockout kit via CRISPR

Ggps1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ggps1 - mouse gene knockout kit via CRISPR

Ggps1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GGPP synthetase (transcript variant 2)

  Recombinant protein of human geranylgeranyl diphosphate synthase 1 (GGPS1), transcript variant 2  
GGPP synthetase Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

GGPP synthetase (transcript variant 2)

  Recombinant protein of human geranylgeranyl diphosphate synthase 1 (GGPS1), transcript variant 2  
GGPP synthetase Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €399.00
  OriGene Technologies, Inc.

GGPP synthetase (1-300, His-tag)

Recombinant human GGPS1, 1- 300 aa, His-tagged Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

GGPP synthetase (1-300, His-tag)

Recombinant human GGPS1, 1- 300 aa, His-tagged Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

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