GIPC1 antibody

Principal name

GIPC1 antibody

Alternative names for GIPC1 antibody

GIPC, TIP-2, TIP2, C19orf3, RGS19IP1, PDZ domain-containing protein GIPC1, RGS19-interacting protein 1, GAIP C-terminus-interacting protein, RGS-GAIP-interacting protein, Tax interaction protein 2

SwissProt ID

O14908 (Human), Q9Z0G0 (Mouse), Q9Z254 (Rat)

Gene ID

10755 (GIPC1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Prim (Primate), Xen (Xenopus), GP (Guinea Pig)

Available hosts

Mouse, Rabbit, Goat, Chicken

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of GIPC1 antibody

GIPC, for GAIP interacting protein at the C terminus (also designated SEMCAP-1 or synectin), is a PDZ domain containing protein that interacts with RGS-GAIP, a GTPase-activating protein (GAP) for G(a i) subunits. GIPC was also identified as TIP-2, a protein that interacts with the viral oncoprotein TAX, which transactivates viral and cellular promoters through interactions with various transcription factors. PDZ domain-containing proteins are primarily localized to cell-cell junctions in epithelial cells and neurons where they coordinate the assembly of multiprotein complexes. GIPC specifically localizes to clusters of vesicles near the plasma membrane and participates in G protein-coupled signaling pathway involved in regulating clathrin-coated vesicular trafficking. GIPC also associates with membrane bound semaphorin F (M-SemF), which is involved in neuronal axon growth, and it appears to regulate the subcellular distribution of M-SemF in the brain.

General readings

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Wu, D., et al. J. Biol. Chem. 285(37):28643-28650(2010)
Razanskas, R., et al. Arch. Virol. 155(2):247-250(2010)
Puri, C., et al. Oncogene 29(2):188-200(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GIPC1 antibody

Immunohistochemistry: GIPC1 Antibody [NB100-1353] - NB100-1353 (10ug/ml) staining of paraffin embedded Human Kidney. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining. Goat IgG Aff - Purified Hu E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

GIPC1 (C-term) antibody

TA302499 staining (0.03µg/ml) of human HeLa cell lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GIPC1 antibody

Sample (30 ug of whole cell lysate). A: A431 . B: Hela. 10% SDS PAGE. TA308356 diluted at 1:1000. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GIPC1 antibody

WB Suggested Anti-GIPC1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

GIPC1 (100-333) antibody

GIPC1 Rabbit IgG Aff - Purified Hu, Prim, Rt ICC/IF, IP, WB
50 µg / €340.00
  Acris Antibodies GmbH

GIPC1 (N-term) antibody

Western blot analysis of GIPC1 Antibody (N-term) Cat.-No AP51843PU-N in mouse bladder tissue lysates (35ug/lane). This demonstrates the GIPC1 antibody detected the GIPC1 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GIPC1 antibody

RGS19IP1 polyclonal antibody (A02), Lot # 050928JC01 Western Blot analysis of GIPC1 expression in 293 ( Cat # L026V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

GIPC1 antibody

Western Blot analysis of GIPC1 expression in transfected 293T cell line (H00010755-T01) by GIPC1 MaxPab polyclonal antibody.

Lane 1: GIPC1 transfected lysate(36.63 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

GIPC1 antibody

Western Blot analysis of GIPC1 expression in transfected 293T cell line (H00010755-T01) by GIPC1 MaxPab polyclonal antibody.

Lane 1: GIPC1 transfected lysate(36.63 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

GIPC1 antibody

GIPC1 polyclonal antibody ( Cat # PAB6538 ) staining ( 0.03 µg/ml ) of human HeLa cell lysate ( RIPA buffer, 35 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

GIPC1 antibody

Human Jurkat; WB Suggested Anti-GIPC1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Jurkat cell lysate; GIPC1 antibody - N-terminal region (ARP40601_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

GIPC1 antibody

GIPC1 Rabbit Aff - Purified Can, Hu, Ms, Rt, Ze WB
50 µg / €440.00
  Novus Biologicals Inc.

GIPC1 antibody

Immunohistochemistry-Paraffin: GIPC1 Antibody [NBP1-91941] - Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes . Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GIPC1 (transcript variant 5)

GIPC1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

GIPC1 (transcript variant 1)

GIPC1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

GIPC1 (transcript variant 3)

GIPC1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

GIPC1 (1-333, His-tag)

GIPC1 Human Purified > 95 % by SDS – PAGE E. coli
0.25 mg / €1,000.00
  Acris Antibodies GmbH

GIPC1 (1-333, His-tag)

GIPC1 Human Purified > 95 % by SDS – PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

GIPC1

GIPC1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

GIPC1

GIPC1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

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