GIT1 antibody

Principal name

GIT1 antibody

Alternative names for GIT1 antibody

GRK-interacting protein 1, CAT1, ARF GTPase-activating protein GIT1, G protein-coupled receptor kinase-interactor 1, Cool-associated and tyrosine-phosphorylated protein 1

SwissProt ID

Q68FF6 (Mouse), Q9Y2X7 (Human), Q9Z272 (Rat)

Gene ID

28964 (GIT1), 83709 (Git1), 216963

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Dot blot (Dot), Enzyme Immunoassay (E), Immunoprecipitation (IP), Frozen Sections (C)

Background of GIT1 antibody

G-protein coupled receptor (GPCR) kinase interacting proteins 1 and 2 (GIT1 and GIT2) are highly conserved, ubiquitous scaffold proteins involved in localized signaling to help regulate focal contact assembly and cytoskeletal dynamics.
GIT proteins contain multiple interaction domains that allow interaction with small GTPases (including ARF, Rac and cdc42), kinases (such as PAK and MEK), the Rho family GEF PIX, and the focal adhesion protein paxillin (reviewed in 1). GIT1 is localized to focal adhesions, cytoplasmic complexes and membrane protrusions, and regulates cell protrusion formation and cell migration (2). GIT1 has also been implicated in neuronal functions including synapse formation (3) and the pathology of Huntington disease (4). Huntington disease is a genetic neurodegenerative condition involving a mutation in the huntington gene. The huntington gene product (htt) is ubiquitinated and degraded in human Huntington disease brains (5). Htt interacts directly with GIT1 causing enhanced htt proteolysis, indicating that GIT1 distribution and function may contribute to Huntington disease pathology 
(4).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GIT1 antibody

Adult rat brain membrane immunoblot Mouse IgG1 N39B/8 Supernatant Hu, Ms, Rt C, IP, WB
5 ml / €460.00
  Antibodies Incorporated

NeuroMab

GIT1 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 N39B/8 Purified Hu, Ms, Rt C, IP, WB
0.1 ml / €540.00
  Antibodies Incorporated

NeuroMab

GIT1 antibody

  Rabbit polyclonal GIT1 antibody  
GIT1 Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GIT1 (375-770) antibody

  Mouse Monoclonal Anti-GIT1 Antibody  
Western blot of rat brain membrane lysates showing the detection of ~90 kDa GIT1 protein using Anti-GIT1 antibody [S39B-8] (TA326533).??Lane 1: MW ladder. Lane 2: Anti-GIT1 (1:1000). Lane 3: Negative control. Load: 33 µ RBM per lane. Block: 5% milk + TBST Mouse IgG1 S39B-8 Purified Hu, Ms, Rt IP, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GIT1 antibody

  Rabbit Polyclonal Anti-GIT1 Antibody  
Host: Rabbit; Target Name: Git1; Sample Tissue: Rat Pancreas lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

GIT1 pTyr554 antibody

Dot blot analysis of anti-Phospho-GIT1 pTyr554 Antibody (Cat.#AP12965PU-N) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. Rabbit Ig Aff - Purified Hu
0.4 ml / €370.00
  Acris Antibodies GmbH

GIT1 antibody

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with GIT1 Antibody (Y510), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

GIT1 - human gene knockout kit via CRISPR

GIT1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GIT1 - human gene knockout kit via CRISPR

GIT1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GIT1 (transcript variant 2)

  Recombinant protein of human G protein-coupled receptor kinase interacting ArfGAP 1 (GIT1), transcript variant 2  
GIT1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

GIT1 overexpression lysate

GIT1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Git1 (GFP-tagged) - Mouse G protein-coupled receptor kinase-interactor 1 (Git1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Git1 (GFP-tagged) - Mouse G protein-coupled receptor kinase-interactor 1 (Git1), 200 uL, >10^7 TU/mL  
200 µl / €1,480.00
  OriGene Technologies, Inc.

Lenti ORF particles, Git1 (Myc-DDK-tagged) - Mouse G protein-coupled receptor kinase-interactor 1 (Git1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Git1 (Myc-DDK-tagged) - Mouse G protein-coupled receptor kinase-interactor 1 (Git1), 200 uL, >10^7 TU/mL  
200 µl / €1,330.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Git1 (GFP-tagged ORF) - Rat G protein-coupled receptor kinase interacting ArfGAP 1 (Git1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Git1 (GFP-tagged ORF) - Rat G protein-coupled receptor kinase interacting ArfGAP 1 (Git1), 200 uL, >10^7 TU/mL  
200 µl / €1,470.00
  OriGene Technologies, Inc.

Lenti ORF particles, Git1 (Myc-DDK-tagged ORF) - Rat G protein-coupled receptor kinase interacting ArfGAP 1 (Git1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Git1 (Myc-DDK-tagged ORF) - Rat G protein-coupled receptor kinase interacting ArfGAP 1 (Git1), 200 uL, >10^7 TU/mL  
200 µl / €1,325.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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