GJA3 / Cx46 antibody

Principal name

GJA3 / Cx46 antibody

Alternative names for GJA3 / Cx46 antibody

Gap junction alpha-3 protein, Connexin-46

SwissProt ID

P29414 (Rat), P41987 (Bovin), Q64448 (Mouse), Q9TU17 (Sheep), Q9Y6H8 (Human)

Gene ID

2700 (GJA3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Eq (Equine), Por (Porcine), Ye (Yeast)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C), Flow Cytometry (F)

Background of GJA3 / Cx46 antibody

The connexin family of proteins form hexameric complexes called “connexons” that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane α-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20 connexin isoforms produces channels with distinct permeabilities and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another. Consequently, a wide variety of malignant phenotypes associate with decreased connexin expression and gap junction communication, dependent on the particular connexin that is affected. For instance, deletion of the gene encoding connexin 46, normally expressed in the lens, produces severe cataracts.

General readings

Fritz,G.A., (2007) Rofo 179 (6), 637-638

11 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GJA3 / Cx46 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using GJA3 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

GJA3 / Cx46 antibody

WB Suggested Anti-GJA3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: 721_B cell lysate GJA3 is supported by BioGPS gene expression data to be expressed in 721_B Rabbit IgG Purified Eq, Hu, Ms, Por, Rt, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

GJA3 / Cx46 (N-term) antibody

Formalin-fixed and paraffin-embedded human breast carcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P
0.4 ml / €370.00
  Acris Antibodies GmbH

GJA3 / Cx46 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with GJA3 polyclonal antibody ( Cat # PAB3583 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit IgG Purified Hu E, P
0.4 ml / €390.00
  Abnova Taiwan Corp.

GJA3 / Cx46 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using GJA3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
50 µg / €205.00
  Assay Biotech

GJA3 / Cx46 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using GJA3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €310.00
  Assay Biotech

GJA3 / Cx46 antibody

Human 721_B; WB Suggested Anti-GJA3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: 721_B cell lysate. GJA3 is supported by BioGPS gene expression data to be expressed in 721_B.; GJA3 antibody - N-terminal region (ARP36626_P050) in Human 721_B cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

GJA3 / Cx46 antibody

GJA3 / Cx46 Rabbit IgG Aff - Purified Hu P, WB
0.1 mg / €290.00
  Boster Immunoleader

GJA3 / Cx46 antibody

GJA3 / Cx46 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €360.00
  Novus Biologicals Inc.

GJA3 / Cx46 antibody

GJA3 / Cx46 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P
50 µg / €290.00
  Novus Biologicals Inc.

GJA3 / Cx46 antibody

Western Blot: GJA3 Antibody [NBP1-59197] - This Anti-GJA3 antibody was used in Western Blot of 721_B tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

11 Item(s)

per page
  • LinkedIn