GJA5 / Cx40 antibody

Principal name

GJA5 / Cx40 antibody

Alternative names for GJA5 / Cx40 antibody

Gap junction alpha-5 protein, Connexin-40

SwissProt ID

P18860 (Chick), P28234 (Rat), P33725 (Canfa), P36382 (Human), Q01231 (Mouse), Q0VCR2 (Bovin)

Gene ID

2702 (GJA5), 50563 (Gja5), 14613

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Rt (Rat), Ms (Mouse), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Sheep

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of GJA5 / Cx40 antibody

Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell closely packed transmembrane channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. Connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 is designated alpha-1 gap junction protein, whereas CX32 and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43. Connexins have four transmembrane, three intracellular, and two extracellular regions. Different tissues express different connexins, though tissue specificities overlap, and a given tissue or cell can express several different connexins. Developmental regulation of at least some of the connexin genes has been found. Embryo implantation is regulated in part by temporally changing patterns of expression of connexins in the embryo and the maternal decidua.

General readings

Makita,N., et al., (2005) Acta Neurochir. Suppl. 2 (10), 1128-1134

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GJA5 / Cx40 antibody

  Rabbit Polyclonal Anti-Connexin-40  
Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) heart lysates: 1-2. Anti-Connexin-40 antibody, (1:200). 3-4. Anti-Connexin-40 antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GJA5 / Cx40 antibody

  Rabbit Polyclonal Anti-GJA5 Antibody  
WB Suggested Anti-GJA5 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Lung Rabbit IgG Purified Bov, Can, Eq, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

GJA5 / Cx40 (N-term) antibody

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with GJA5 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

GJA5 - human gene knockout kit via CRISPR

GJA5 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GJA5 - human gene knockout kit via CRISPR

GJA5 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GJA5 - human gene knockout kit via CRISPR

GJA5 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GJA5 - human gene knockout kit via CRISPR

GJA5 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gja5 - mouse gene knockout kit via CRISPR

Gja5 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Gja5 - mouse gene knockout kit via CRISPR

Gja5 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gja5 - mouse gene knockout kit via CRISPR

Gja5 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gja5 - mouse gene knockout kit via CRISPR

Gja5 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, GJA5 (mGFP-tagged) - Human gap junction protein, alpha 5, 40kDa (GJA5), transcript variant A, 200 uL, >10^7 TU/mL

Lenti ORF particles, GJA5 (mGFP-tagged) - Human gap junction protein, alpha 5, 40kDa (GJA5), transcript variant A, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, GJA5 (mGFP-tagged) - Human gap junction protein, alpha 5, 40kDa (GJA5), transcript variant B, 200 uL, >10^7 TU/mL

Lenti ORF particles, GJA5 (mGFP-tagged) - Human gap junction protein, alpha 5, 40kDa (GJA5), transcript variant B, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, GJA5 (Myc-DDK tagged) - Human gap junction protein, alpha 5, 40kDa (GJA5), transcript variant A , 200 uL, >10^7 TU/mL

Lenti ORF particles, GJA5 (Myc-DDK tagged) - Human gap junction protein, alpha 5, 40kDa (GJA5), transcript variant A , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, GJA5 (Myc-DDK tagged) - Human gap junction protein, alpha 5, 40kDa (GJA5), transcript variant B , 200 uL, >10^7 TU/mL

Lenti ORF particles, GJA5 (Myc-DDK tagged) - Human gap junction protein, alpha 5, 40kDa (GJA5), transcript variant B , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Gja5 (GFP-tagged) - Mouse gap junction protein, alpha 5 (Gja5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gja5 (GFP-tagged) - Mouse gap junction protein, alpha 5 (Gja5), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Gja5 (Myc-DDK-tagged) - Mouse gap junction protein, alpha 5 (Gja5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gja5 (Myc-DDK-tagged) - Mouse gap junction protein, alpha 5 (Gja5), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Gja5 (GFP-tagged ORF) - Rat gap junction protein, alpha 5 (Gja5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gja5 (GFP-tagged ORF) - Rat gap junction protein, alpha 5 (Gja5), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Gja5 (Myc-DDK-tagged ORF) - Rat gap junction protein, alpha 5 (Gja5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gja5 (Myc-DDK-tagged ORF) - Rat gap junction protein, alpha 5 (Gja5), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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