GJA5 / Cx40 antibody

Principal name

GJA5 / Cx40 antibody

Alternative names for GJA5 / Cx40 antibody

Gap junction alpha-5 protein, Connexin-40

SwissProt ID

P18860 (Chick), P28234 (Rat), P33725 (Canfa), P36382 (Human), Q01231 (Mouse), Q0VCR2 (Bovin)

Gene ID

2702 (GJA5), 50563 (Gja5)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Rt (Rat), Ms (Mouse), Gt (Goat), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Sheep

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of GJA5 / Cx40 antibody

Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell closely packed transmembrane channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. Connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 is designated alpha-1 gap junction protein, whereas CX32 and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43. Connexins have four transmembrane, three intracellular, and two extracellular regions. Different tissues express different connexins, though tissue specificities overlap, and a given tissue or cell can express several different connexins. Developmental regulation of at least some of the connexin genes has been found. Embryo implantation is regulated in part by temporally changing patterns of expression of connexins in the embryo and the maternal decidua.

General readings

Makita,N., et al., (2005) Acta Neurochir. Suppl. 2 (10), 1128-1134

9 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GJA5 / Cx40 antibody

Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) heart lysates: 1-2. Anti-Connexin-40 antibody, (1:200). 3-4. Anti-Connexin-40 antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GJA5 / Cx40 antibody

WB Suggested Anti-GJA5 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Lung Rabbit IgG Purified Bov, Can, Eq, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

GJA5 / Cx40 (N-term) antibody

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with GJA5 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GJA5 / Cx40 antibody

GJA5 / Cx40 Sheep Rt ICC/IF, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

GJA5 / Cx40 antibody

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with GJA5 polyclonal antibody ( Cat # PAB3589 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

GJA5 / Cx40 antibody

Human Lung; WB Suggested Anti-GJA5 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Lung; GJA5 antibody - N-terminal region (ARP36610_P050) in Human Lung cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu WB
50 µg / €350.00
  AVIVA Systems Biology

GJA5 / Cx40 antibody

GJA5 / Cx40 Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

GJA5 / Cx40 antibody

GJA5 / Cx40 Rabbit Purified Ms P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

GJA5 / Cx40 antibody

GJA5 / Cx40 Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

9 Item(s)

per page
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