GJA8 / Cx50 antibody

Principal name

GJA8 / Cx50 antibody

Alternative names for GJA8 / Cx50 antibody

Gap junction alpha-8 protein, Connexin-50, Lens fiber protein MP70

SwissProt ID

P28236 (Mouse), P36381 (Chick), P48165 (Human), P55917 (Sheep), Q8K4Q9 (Rat)

Gene ID

2703 (GJA8), 14616 (Gja8)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), GP (Guinea Pig), Rb (Rabbit), Sh (Sheep), Ye (Yeast), Ze (Zebrafish), Eq (Equine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of GJA8 / Cx50 antibody

The connexin family of proteins form hexameric complexes called “connexons” that facilitate movement of low molecular weight proteins between cells via gap junctions (1). Connexin proteins share a common topology of 4 transmembrane alpha-helical domains, two extracellular loops, a cytoplasmic loop, and cytoplasmic N- and C-termini (2). Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions (2). Each of the approximately 20 connexin isoforms produces channels with distinct permeabilities and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another (2). Consequently, a wide variety of malignant phenotypes associate with decreased connexin expression and gap junction communication, dependent on the particular connexin that is effected (3, 2). For instance, deletion of the gene encoding connexin 50, normally expressed in the lens, produces cataracts, though not as severe as with deletion of connexin 46 (4).

13 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GJA8 / Cx50 antibody

WB Suggested Anti-GJA8 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Can, Eq, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

GJA8 / Cx50 (C-term) antibody

Formalin-fixed and paraffin-embedded human breast carcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GJA8 / Cx50 antibody

GJA8 / Cx50 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

GJA8 / Cx50 antibody

GJA8 / Cx50 Mouse IgG2a 8A10 Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GJA8 / Cx50 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with GJA8 polyclonal antibody ( Cat # PAB3595 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu, Ms E, P
0.4 ml / €390.00
  Abnova Taiwan Corp.

GJA8 / Cx50 antibody

Human HepG2; WB Suggested Anti-GJA8 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: HepG2 cell lysate; GJA8 antibody - middle region (ARP36612_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

GJA8 / Cx50 (N-term) antibody

Mouse Uterus; WB Suggested Anti-Gja8 Antibody Titration: 0.2-1 ug/ml. Positive Control: Mouse Uterus; Gja8 antibody - N-terminal region (ARP42820_P050) in Mouse Uterus cells using Western Blot Rabbit Aff - Purified Ms WB
50 µg / €350.00
  AVIVA Systems Biology

GJA8 / Cx50 antibody

Western Blot: GJA8 Antibody [NBP1-59201] - This Anti-GJA8 antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GJA8 / Cx50

GJA8 / Cx50 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

GJA8 / Cx50

GJA8 / Cx50 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

GJA8 / Cx50

GJA8 / Cx50 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

GJA8 / Cx50

GJA8 / Cx50 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

GJA8 / Cx50

GJA8 / Cx50 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

13 Item(s)

per page
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