GJB1 / Cx32 antibody

Principal name

GJB1 / Cx32 antibody

Alternative names for GJB1 / Cx32 antibody

Gap junction beta-1 protein, Connexin-32, GAP junction 28 kDa liver protein

SwissProt ID

O18968 (Bovin), P08033 (Rat), P08034 (Human), P28230 (Mouse)

Gene ID

2705 (GJB1), 29584 (Gjb1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Rb (Rabbit), Chk (Chicken), Mky (Monkey), Por (Porcine), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of GJB1 / Cx32 antibody

Gap junctions are aggregations of intercellular channels that directly connect the cytoplasm of adjacent cells. Gap junctions coordinate cellular and organ function in tissues and are involved in metabolic cooperation between cells, synchronization of cellular physiological activities, growth control and developmental regulation. The gap junction channels allow intercellular exchange of ions, nucleotides and small molecules between adjacent cells. Unlike other membrane channels, intercellular channels span two plasma membranes and require the contribution of hemichannels, called connexons, from both participating cells. These channels are permeate to molecules as large as 1 kD, and they have been detected in virtually every cell type in mammals, except mature skeletal muscle, spermatozoa and erythrocytes. Two connexons interact in the extracellular space to form the complete intercellular channel. Each connexon is composed of six similar or identical proteins, which are termed connexins. Connexins (Cx) are a multi-gene family of highly related proteins ranging between molecular weights of 26 and 70 kD. At least a dozen distinct connexin genes have been identified and many are expressed in a tissue-specific manner. Two distinct lineages have been identified in mammals. One termed class I or beta group to which Cx26, Cx30, Cx31, Cx31.1 and Cx32 belong, and the other termed class II or alpha group, represented by Cx33, Cx37, Cx40, Cx43 and Cx46.

General readings

1. Corcos, I. A.; Lafreniere, R. G.; Begy, C. R.; Loch-Caruso, R.; Willard, H. F.; Glover, T. W. : Refined localization of human connexin 32 gene locus, GJB1, to Xq13.1. Genomics 13: 479-480, 1992.
2 Bondurand, N.; Girard, M.; Pingault, V.; Lemort, N.; Dubourg, O.; Goossens, M. : Human connexin 32, a gap junction protein altered in the X-linked form of Charcot-Marie-Tooth disease, is directly regulated by the transcription factor SOX10. Hum. Molec. Genet. 10: 2783-2795, 2001.
3. Fairweather, N.; Bell, C.; Cochrane, S.; Chelly, J.; Wang, S.; Mostacciuolo, M. L.; Monaco, A. P.; Haites, N. E. : Mutations in the connexin 32 gene in X-linked dominant Charcot-Marie-Tooth disease (CMTX1). Hum. Molec. Genet. 3: 29-34, 1994.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GJB1 / Cx32 antibody

Immunohistochemistry analysis of Connexin-32 antibody (Cat.-No AP20645PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GJB1 / Cx32 antibody

Western blot analysis of rat liver lysate: 1. Anti-Connexin-32 antibody, (1:200). 2. Anti-Connexin-32 antibody, preincubated with the control peptide antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GJB1 / Cx32 antibody

WB Suggested Anti-GJB1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

GJB1 / Cx32 antibody

WB Suggested Anti-GJB1 Antibody Titration: 2.5 ug/ml; ELISA Titer: 1:312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GJB1 / Cx32 antibody

Western blot analysis of Connexin 32 expression in LOVO cells, Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GJB1 / Cx32 antibody

GJB1 / Cx32 Mouse IgG1 CXN-32 Purified Hu, Ms, Rt C, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

GJB1 / Cx32 antibody

GJB1 / Cx32 Mouse IgG1 2B9 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

GJB1 / Cx32 antibody

Detection limit for recombinant GST tagged GJB1 is approximately 1ng/ml as a capture antibody. Mouse IgG1 1F5 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

GJB1 / Cx32 antibody

Human Skin; Skin; GJB1 antibody - middle region (ARP36599_P050) in Human Skin cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Rb, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

GJB1 / Cx32 antibody

Human Intestine; GJB1 antibody - C-terminal region (ARP36600_T100) in Human Intestine cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rb, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

GJB1 / Cx32 antibody

GJB1 / Cx32 Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

GJB1 / Cx32 antibody

Immunohistochemical analysis of Connexin 32 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Mky, Ms, Por, Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

GJB1 / Cx32 antibody

Immunohistochemical analysis of Connexin 32 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Mky, Ms, Por, Rt P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

GJB1 / Cx32 antibody

Immunohistochemical analysis of Connexin 32 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Mky, Ms, Por, Rt P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

GJB1 / Cx32 antibody

Immunohistochemistry: Connexin-32 Antibody [NBP1-19791] -  Connexin-32 Antibody [NBP1-19791] - paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

GJB1 / Cx32 antibody

GJB1 / Cx32 Rabbit Purified Can, Hu, Ms, Rt P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

GJB1 / Cx32 antibody

Immunohistochemistry-Paraffin: GJB1 Antibody [NBP1-85531] - Immunohistochemical staining of human kidney shows strong cytoplasmic and extracellular positivity in cells of tubules. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GJB1 / Cx32

GJB1 / Cx32 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

GJB1 / Cx32

GJB1 / Cx32 Human
10 µg / €380.00
  Abnova Taiwan Corp.

GJB1 / Cx32

GJB1 / Cx32 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

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