GJB1 / Cx32 antibody

Principal name

GJB1 / Cx32 antibody

Alternative names for GJB1 / Cx32 antibody

Gap junction beta-1 protein, Connexin-32, GAP junction 28 kDa liver protein

SwissProt ID

O18968 (Bovin), P08033 (Rat), P08034 (Human), P28230 (Mouse)

Gene ID

2705 (GJB1), 29584 (Gjb1), 14618

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat), Mky (Monkey), Por (Porcine), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of GJB1 / Cx32 antibody

Gap junctions are aggregations of intercellular channels that directly connect the cytoplasm of adjacent cells. Gap junctions coordinate cellular and organ function in tissues and are involved in metabolic cooperation between cells, synchronization of cellular physiological activities, growth control and developmental regulation. The gap junction channels allow intercellular exchange of ions, nucleotides and small molecules between adjacent cells. Unlike other membrane channels, intercellular channels span two plasma membranes and require the contribution of hemichannels, called connexons, from both participating cells. These channels are permeate to molecules as large as 1 kD, and they have been detected in virtually every cell type in mammals, except mature skeletal muscle, spermatozoa and erythrocytes. Two connexons interact in the extracellular space to form the complete intercellular channel. Each connexon is composed of six similar or identical proteins, which are termed connexins. Connexins (Cx) are a multi-gene family of highly related proteins ranging between molecular weights of 26 and 70 kD. At least a dozen distinct connexin genes have been identified and many are expressed in a tissue-specific manner. Two distinct lineages have been identified in mammals. One termed class I or beta group to which Cx26, Cx30, Cx31, Cx31.1 and Cx32 belong, and the other termed class II or alpha group, represented by Cx33, Cx37, Cx40, Cx43 and Cx46.

General readings

1. Corcos, I. A.; Lafreniere, R. G.; Begy, C. R.; Loch-Caruso, R.; Willard, H. F.; Glover, T. W. : Refined localization of human connexin 32 gene locus, GJB1, to Xq13.1. Genomics 13: 479-480, 1992.
2 Bondurand, N.; Girard, M.; Pingault, V.; Lemort, N.; Dubourg, O.; Goossens, M. : Human connexin 32, a gap junction protein altered in the X-linked form of Charcot-Marie-Tooth disease, is directly regulated by the transcription factor SOX10. Hum. Molec. Genet. 10: 2783-2795, 2001.
3. Fairweather, N.; Bell, C.; Cochrane, S.; Chelly, J.; Wang, S.; Mostacciuolo, M. L.; Monaco, A. P.; Haites, N. E. : Mutations in the connexin 32 gene in X-linked dominant Charcot-Marie-Tooth disease (CMTX1). Hum. Molec. Genet. 3: 29-34, 1994.

  1. Quick-Filters:
  2. Highly Validated (1)

Items 1 to 20 of 26 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GJB1 / Cx32 antibody

Immunohistochemistry analysis of Connexin-32 antibody (Cat.-No AP20645PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GJB1 / Cx32 antibody

  Rabbit Polyclonal Anti-Connexin-32  
Western blot analysis of rat liver lysate: 1. Anti-Connexin-32 antibody, (1:200). 2. Anti-Connexin-32 antibody, preincubated with the control peptide antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GJB1 / Cx32 antibody

  Rabbit Polyclonal Anti-GJB1 Antibody  
WB Suggested Anti-GJB1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

GJB1 / Cx32 antibody

  Rabbit Polyclonal Anti-GJB1 Antibody  
WB Suggested Anti-GJB1 Antibody Titration: 2.5 ug/ml; ELISA Titer: 1:312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GJB1 / Cx32 antibody

  Rabbit Polyclonal Anti-Connexin 32 Antibody  
Western blot analysis of Connexin 32 expression in LOVO cells, Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GJB1 / Cx32 antibody

  Mouse monoclonal Anti-Cx32 Clone Connexin32  
GJB1 / Cx32 Mouse IgG Connexin32 Purified Chk, Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GJB1 / Cx32 antibody

GJB1 / Cx32 Mouse IgG1 CXN-32 Purified Hu, Ms, Rt C, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

GJB1 - human gene knockout kit via CRISPR

GJB1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GJB1 - human gene knockout kit via CRISPR

GJB1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GJB1 - human gene knockout kit via CRISPR

GJB1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GJB1 - human gene knockout kit via CRISPR

GJB1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gjb1 - mouse gene knockout kit via CRISPR

Gjb1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Gjb1 - mouse gene knockout kit via CRISPR

Gjb1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gjb1 - mouse gene knockout kit via CRISPR

Gjb1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gjb1 - mouse gene knockout kit via CRISPR

Gjb1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

GJB1 overexpression lysate

GJB1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

GJB1 overexpression lysate

GJB1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

GJB1 overexpression lysate

GJB1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, GJB1 (mGFP-tagged) - Human gap junction protein, beta 1, 32kDa (GJB1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, GJB1 (mGFP-tagged) - Human gap junction protein, beta 1, 32kDa (GJB1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, GJB1 (mGFP-tagged)-Human gap junction protein, beta 1, 32kDa (GJB1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, GJB1 (mGFP-tagged)-Human gap junction protein, beta 1, 32kDa (GJB1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Items 1 to 20 of 26 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn