GJC1 / Cx45 antibody

Principal name

GJC1 / Cx45 antibody

Alternative names for GJC1 / Cx45 antibody

Gap junction gamma-1 protein, Gap junction alpha-7 protein, Connexin-45, GJA7

SwissProt ID

A4GVD1 (Pig), P18861 (Chick), P28228 (Canfa), P28229 (Mouse), P36383 (Human), Q2HJ66 (Bovin)

Gene ID

10052 (GJC1), 14615 (Gjc1)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Por (Porcine), Rt (Rat), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of GJC1 / Cx45 antibody

Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell closely packed transmembrane channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. Connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 is designated alpha-1 gap junction protein, whereas CX32 and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43. Connexins have four transmembrane, three intracellular, and two extracellular regions. Different tissues express different connexins, though tissue specificities overlap, and a given tissue or cell can express several different connexins. Developmental regulation of at least some of the connexin genes has been found. Embryo implantation is regulated in part by temporally changing patterns of expression of connexins in the embryo and the maternal decidua.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GJC1 / Cx45 antibody

  Rabbit Polyclonal Anti-GJC1 Antibody  
WB Suggested Anti-GJC1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

GJC1 / Cx45 (N-term) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GJC1 / Cx45 antibody

Immunohistochemistry analysis of Connexin-45 antibody (Cat.-No.: AP20594PU-N) in paraffin-embedded Human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

GJC1 - human gene knockout kit via CRISPR

GJC1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GJC1 - human gene knockout kit via CRISPR

GJC1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gjc1 - mouse gene knockout kit via CRISPR

Gjc1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Gjc1 - mouse gene knockout kit via CRISPR

Gjc1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gjc1 - mouse gene knockout kit via CRISPR

Gjc1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gjc1 - mouse gene knockout kit via CRISPR

Gjc1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Gjc1 (GFP-tagged) - Mouse gap junction protein, gamma 1 (Gjc1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Gjc1 (GFP-tagged) - Mouse gap junction protein, gamma 1 (Gjc1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,170.00
  OriGene Technologies, Inc.

Lenti ORF particles, Gjc1 (GFP-tagged) - Mouse gap junction protein, gamma 1 (Gjc1), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, Gjc1 (GFP-tagged) - Mouse gap junction protein, gamma 1 (Gjc1), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Gjc1 (Myc-DDK-tagged) - Mouse gap junction protein, gamma 1 (Gjc1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Gjc1 (Myc-DDK-tagged) - Mouse gap junction protein, gamma 1 (Gjc1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, Gjc1 (Myc-DDK-tagged) - Mouse gap junction protein, gamma 1 (Gjc1), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, Gjc1 (Myc-DDK-tagged) - Mouse gap junction protein, gamma 1 (Gjc1), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

13 Item(s)

per page
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