GJC1 / Cx45 antibody

Principal name

GJC1 / Cx45 antibody

Alternative names for GJC1 / Cx45 antibody

Gap junction gamma-1 protein, Gap junction alpha-7 protein, Connexin-45, GJA7

SwissProt ID

A4GVD1 (Pig), P18861 (Chick), P28228 (Canfa), P28229 (Mouse), P36383 (Human), Q2HJ66 (Bovin)

Gene ID

10052 (GJC1)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Por (Porcine), Rt (Rat), Rb (Rabbit), Eq (Equine), GP (Guinea Pig)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Immunoprecipitation (IP)

Background of GJC1 / Cx45 antibody

Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell closely packed transmembrane channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. Connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 is designated alpha-1 gap junction protein, whereas CX32 and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43. Connexins have four transmembrane, three intracellular, and two extracellular regions. Different tissues express different connexins, though tissue specificities overlap, and a given tissue or cell can express several different connexins. Developmental regulation of at least some of the connexin genes has been found. Embryo implantation is regulated in part by temporally changing patterns of expression of connexins in the embryo and the maternal decidua.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GJC1 / Cx45 antibody

WB Suggested Anti-GJC1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

GJC1 / Cx45 (N-term) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GJC1 / Cx45 antibody

Immunohistochemistry analysis of Connexin-45 antibody (Cat.-No.: AP20594PU-N) in paraffin-embedded Human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GJC1 / Cx45 antibody

GJA7 polyclonal antibody (A01), Lot # 060608JCS1 Western Blot analysis of GJA7 expression in 293 ( Cat # L026V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

GJC1 / Cx45 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with GJC1 polyclonal antibody ( Cat # PAB3593 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

GJC1 / Cx45 antibody

Human HepG2; WB Suggested Anti-GJC1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:12500. Positive Control: HepG2 cell lysate; GJC1 antibody - middle region (ARP36615_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Por WB
50 µg / €350.00
  AVIVA Systems Biology

GJC1 / Cx45 antibody

GJC1 / Cx45 Rabbit IgG Hu WB
0.1 ml / €340.00
  Novus Biologicals Inc.

GJC1 / Cx45 antibody

Western Blot: Connexin-45 Antibody [NBP1-59282] - This Anti-GJC1 antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GJC1 / Cx45

GJC1 / Cx45 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

GJC1 / Cx45

GJC1 / Cx45 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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