GLE1 / GLE1L antibody

Principal name

GLE1 / GLE1L antibody

Alternative names for GLE1 / GLE1L antibody

Nucleoporin GLE1, GLE1-like protein

SwissProt ID

Q3ZBK7 (Bovin), Q4KLN4 (Rat), Q53GS7 (Human), Q8R322 (Mouse)

Gene ID

2733 (GLE1), 74412 (Gle1), 362098

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Eq (Equine), Por (Porcine), Ye (Yeast)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of GLE1 / GLE1L antibody

GLE1 is a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm.This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

General readings

Nousiainen,H.O., (2008) Nat. Genet. 40 (2), 155-157

20 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GLE1 / GLE1L (C-term) antibody

  Rabbit Polyclonal Gle1 Antibody  
Western blot analysis of Gle1 in mouse brain tissue lysate with Gle1 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GLE1 / GLE1L (Center) antibody

  Rabbit Polyclonal Gle1 Antibody  
Western blot analysis of Gle1 in 293 cell lysate with Gle1 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GLE1 / GLE1L antibody

  Rabbit polyclonal antibody to GLE1 (GLE1 RNA export mediator homolog (yeast))  
Sample (30 ug of whole cell lysate). A: HeLa. 7.5% SDS PAGE. TA307943 diluted at 1:1000 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GLE1 / GLE1L antibody

  Rabbit Polyclonal Anti-GLE1 Antibody  
WB Suggested Anti-GLE1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Placenta Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rt, Ye WB
50 µg / €325.00
  OriGene Technologies, Inc.

GLE1 / GLE1L (C-term) antibody

Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

GLE1 / GLE1L antibody

Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

GLE1 - human gene knockout kit via CRISPR

GLE1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GLE1 - human gene knockout kit via CRISPR

GLE1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gle1 - mouse gene knockout kit via CRISPR

Gle1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Gle1 - mouse gene knockout kit via CRISPR

Gle1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gle1 - mouse gene knockout kit via CRISPR

Gle1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gle1 - mouse gene knockout kit via CRISPR

Gle1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GLE1 / GLE1L (transcript variant 1)

  Recombinant protein of human GLE1 RNA export mediator homolog (yeast) (GLE1), transcript variant 1  
GLE1 / GLE1L Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

GLE1 overexpression lysate

GLE1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, GLE1 (mGFP-tagged) - Human GLE1 RNA export mediator homolog (yeast) (GLE1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, GLE1 (mGFP-tagged) - Human GLE1 RNA export mediator homolog (yeast) (GLE1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, GLE1 (mGFP-tagged)-Human GLE1 RNA export mediator homolog (yeast) (GLE1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, GLE1 (mGFP-tagged)-Human GLE1 RNA export mediator homolog (yeast) (GLE1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,330.00
  OriGene Technologies, Inc.

Lenti ORF particles, GLE1 (Myc-DDK tagged) - Human GLE1 RNA export mediator homolog (yeast) (GLE1), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, GLE1 (Myc-DDK tagged) - Human GLE1 RNA export mediator homolog (yeast) (GLE1), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, GLE1 (Myc-DDK-tagged)-Human GLE1 RNA export mediator homolog (yeast) (GLE1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, GLE1 (Myc-DDK-tagged)-Human GLE1 RNA export mediator homolog (yeast) (GLE1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,190.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Gle1 (GFP-tagged ORF) - Rat GLE1 RNA export mediator homolog (yeast) (Gle1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gle1 (GFP-tagged ORF) - Rat GLE1 RNA export mediator homolog (yeast) (Gle1), 200 uL, >10^7 TU/mL  
200 µl / €1,380.00
  OriGene Technologies, Inc.

Lenti ORF particles, Gle1 (Myc-DDK-tagged ORF) - Rat GLE1 RNA export mediator homolog (yeast) (Gle1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gle1 (Myc-DDK-tagged ORF) - Rat GLE1 RNA export mediator homolog (yeast) (Gle1), 200 uL, >10^7 TU/mL  
200 µl / €1,239.00
  OriGene Technologies, Inc.

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