GLP1 receptor antibody

Principal name

GLP1 receptor antibody

Alternative names for GLP1 receptor antibody

Glucagon-like peptide 1 receptor, GLP-1-R, GLP-1R, GLP1R

SwissProt ID

O35659 (Mouse), P32301 (Rat), P43220 (Human)

Gene ID

2740 (GLP1R), 14652 (Glp1r), 25051

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine), GP (Guinea Pig), Rb (Rabbit), Sh (Sheep), Bt (Bat), Chk (Chicken), Eq (Equine), Hst (Hamster), Mky (Monkey), Op (Opossum), Tr (Turkey), Bear

Available hosts

Rabbit, Mouse, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C)

Background of GLP1 receptor antibody

GLP1R, a Glucagon Receptor, has been suggested to affect the feelings of satiety or hunger, sensation of glucose levels, control of glucagon sensitivity of islets, and non insulin-dependent diabetes mellitus. Glucagon-like peptide 1 is an incretin hormone produced by enteroendocrine L-cells in the intestinal mucosa. The hormone is released in response to food intake and plays an important role in maintaining blood glucose homeostasis. Stimulation of the GLP-1R by endogenous hormone induces multiple complementary mechanisms, which together result in a lowering of circulating blood glucose levels. These mechanisms include receptor-mediated enhancement of glucose-induced insulin secretion from pancreatic -cells, inhibition of gastric emptying with a delay in the gastrointestinal resorption of nutrients, inhibition of glucagon secretion, and inhibition of food intake. Desensitization of GLP1R on pancreatic beta-cells is one of the causes of non insulin-dependent diabetes mellitus (NIDDM). GLP1R knockout mice are viable, develop normally, but exhibit increased levels of blood glucose following oral glucose challenge in association with diminished levels of circulating insulin. Recently it has been shown that overexpression of glucagon-like peptide-1 receptor improves learning in rats (During et al. 2003).
GLP1R has been reported in pancreas, brain, heart, kidney, lung, and stomach. ESTs have been isolated from kidney and skin libraries.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GLP1 receptor (extracell. dom.) (N-term) antibody

  Rabbit Polyclonal Anti-GLP1R Antibody (N-Terminus)  
Anti-GLP-1 Receptor / GLP1R antibody IHC of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 3-4 ug/ml. Rabbit Aff - Purified Bov, Elephant, Hst, Hu, Mky, Ms, Por, Rb, Rt, Sh P, WB
50 µg / €400.00
  OriGene Technologies, Inc.

GLP1 receptor antibody

  Rabbit Polyclonal Anti-GLP1R Antibody (N-Terminus)  
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu
50 µg / €400.00
  OriGene Technologies, Inc.

GLP1 receptor antibody

  Rabbit polyclonal anti-GLP1R antibody  
Immunofluorescence analysis of HeLa cells, using GLP1R antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

GLP1 receptor antibody

  Anti-GLP1R Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm, cell membrane. Positive control: Human renal cancer and brain tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human renal cancer and brain tissue using GLP1R antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

GLP1 receptor antibody

  Goat Anti-GLP1R Antibody  
TA326308 (1µg/ml) staining of Human Hippocampus lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GLP1 receptor antibody

  Goat Anti-GLP-1-R (mouse) Antibody  
TA326758 (1µg/ml) staining of Mouse Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Purified Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GLP1 receptor antibody

  Rabbit Polyclonal GLP-1R Antibody  
Western Blot: GLP1R Antibody [TA336864] - WB analysis of GLP1R in human pancreas cell lysate. Rabbit Purified Hu, Ms C, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GLP1 receptor antibody

  Rabbit Polyclonal Anti-Glp1r Antibody  
Host: Rabbit; Target Name: Glp1r; Sample Tissue: Mouse Liver lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rb, Rt, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

GLP1 receptor (3rd Cytopl. Dom.) antibody

  Rabbit Polyclonal Anti-GLP1R Antibody (Cytoplasmic Domain)  
AP23800PU-N GLP1R antibody staining of Formalin-Fixed, Paraffin-Embedded of Human Pancreas. Rabbit Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Hst, Hu, Mky, Ms, Op, Por, Rb, Rt, Sh, Tr P
50 µg / €400.00
  OriGene Technologies, Inc.

GLP1 receptor (C-term) antibody

  Rabbit Polyclonal Anti-GLP1R Antibody (C-Terminus)  
AP23801PU-N GLP1R antibody staining of Formalin-Fixed, Paraffin-Embedded of Human Pancreas. Rabbit Aff - Purified Bear, Bt, Can, Chk, Eq, Hst, Hu, Mky, Ms, Op, Por, Rb, Rt, Tr P
50 µg / €400.00
  OriGene Technologies, Inc.

GLP1 receptor antibody

  Rabbit Polyclonal GLP1R Antibody  
ELISA: GLP1R Antibody Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

GLP1 receptor antibody

Immunohistochemistry: Human pancreas (paraffin section) , stained with AM26732PU-N. Mouse IgG1 1H4 Purified Hu P
0.1 mg / €350.00
  Acris Antibodies GmbH

GLP1 receptor antibody

Immunofluorescence analysis of HeLa cells, using GLP1R Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF
50 µg / €230.00
  Assay Biotech

GLP1 receptor antibody

Immunofluorescence analysis of HeLa cells, using GLP1R Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

GLP1R - human gene knockout kit via CRISPR

GLP1R - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GLP1R - human gene knockout kit via CRISPR

GLP1R - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GLP1R - human gene knockout kit via CRISPR

GLP1R - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GLP1R - human gene knockout kit via CRISPR

GLP1R - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Glp1r - mouse gene knockout kit via CRISPR

Glp1r - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

GLP1R overexpression lysate

GLP1R overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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